SY S M E X S T- 40 00 I

BJ AM G UM PA D. M A RIANNE
NNE
ERICSON GALI. ADRIE
CAMILLE VILLA.
 Content Content Content Content

ADVANTAGE
ADVANTAGE
DESCRIPTION FEATURES TEST/S /DISADVANTAGE
/DISADVANTAGE
DESCRIPTION

The Sysmex St-4000i Automated Hematology System utilizes the

power of fluorescent flow cytometry and hydrodynamic focusing
technologies. Using a unique, state-of-the-art, diode laser bench,
Sysmex fluorescent flow cytometry provides the sensitivity
needed for measuring and differentiating cell types in whole
blood and body fluid samples. Fluorescent technology and
hydrodynamic focusing enable the St-4000i to consistently classify
normal WBC, RBC, PLT populations from abnormal populations,
thereby decreasing the number of manual interventions.
 1 Main Unit
Four
2
2 Sampler Unit
Principle
Units 3 Information Processing Unit

4 Pneumatic Unit
 The Sysmex St-4000i offers medium to high
volume labs an automated hematology system
that can truly meet and exceed their
expectations. The St-4000i streamlines your
workflow by providing testing for up to 100
samples per hour, enabling rapid turn around
time.
 1 Manual Mode
2 Sampler Mode
Five
Modes 3 Manual Closed Mode
4 Capillary Mode
5 Body Fluid Mode
USES

Effective Red Cell

Direct
Disorder Screening High Quality
Hematocrit WBC, A Clear
and Hemoglobin
(HCT) Differentiation
Therapy (HGB) Analysis
Monitoring Measurement
 Specifications
Dimensions/Weight w x h x d {in}/{lbs} Main Unit including sampler:
w x h I'd {in} / {lbs} 20.9" x 24.8" x 28.3" /
130 lbs.

Pneumatic Unit:
11.0 " x 15.7" x 14.0" /37.5 lbs.
Data Storage (IPU:Information 10,000 samples including graphics
Processing Unit)
Sample volumes Closed mode:150 ul
Open mode: 85 ul
Capillary mode: 40 ul
Throughput Whole Blood Mode:100 samples / hour

Body Fluid Mode: 30 samples / hour

 Features

Fluorescent Reticulocyte Count

Known as the “Gold Standard” reticulocyte testing

parameter, the fluorescent reticulocyte count is
available on the ST-4000i. Sysmex provides
on-board retic testing in a dedicated channel,
improving your efficiency in reporting reticulocytes
24 hours per day.
Reticulocyte Hemoglobin (RET- He)

It is a parameter measured in
the RET Channel and is used to
measure the incorporation of
iron into erythrocyte
hemoglobin
 Fluorescent Optical Platelet

The ST-4000i offers a Fluorescent Optical

Platelet (PLT-O) in addition to the traditional
impedance PLT (PLT-I) count. These dual
technologies support maximizing
instrument information from abnormal
patient samples.
 Body Fluid Mode

The ST-4000i analyzer includes a body

fluid specific mode. This mode provides a
reportable RBC, WBC, WBC differential
(polymorphonuclear and mononuclear)
and a total count (TC-BF) for all common
body fluid samples (CSF, synovial and
serous).
TESTS
1 Novel body fluid mode

2 Extended white blood cell differential

3 Extended red blood cell analysis

advantages

1 Speed with efficient handling of a large number of

samples
2 Fast and fully automated

3 Accuracy and precision in quantitative blood tests

4 Ability to perform multiple tests on a single platform

5 Operator independent

6 Compact yet powerful

DISADVANTAGES

Flagging of a laboratory test result demands labour-intensive manual

1
examination of a blood smear.

2 Comments on red cell morphology cannot be generated.

3 Erroneously increased or decreased results due to interfering factors

4 Expensive with high running costs

REFERENCES

 https://www.sysmex-europe.com/products/products-detail/xt4000i.html#:~:

text=The%20XT%2D4000i%20provides%20a,and%20plasma%20cells%2C%20if%20present.

 https://photos.labwrench.com/equipmentManuals/10822-4305.pdf

 https://www.accessdata.fda.gov/cdrh_docs/reviews/K091313.pdf

 https://www.sysmex-mea.com/products/xt-4000i-919.html

 https://www.bioscience.com.pk/topics/hemotology/item/810-advantages-and-disadvantages-of-automated-hemotology-analyzer

 https://www.sysmex.com/US/en/Brochures/Brochure_XT4000i_MKT-10-1138.pdfhttps://

www.sysmexeurope.com/n/fileadmin/media/f100/xtra/Expert_voices_SEG/Xtra_Article_XT_4000i_Pushing_limits_in_routine_lab_haematology_1_.

pdf

 https://www.medwrench.com/equipment/7007/sysmex-xt-4000i

 https://www.sysmex.co.za/fileadmin/media/f112/SEED/English/Sysmex_SEED_automated_body_fluid_analysis_2011.pdf