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Congenital Cataract
Congenital Cataract
2. Classification
3. Causes
• In healthy neonates
• In unwell neonates
IMPORTANT FACTS
Capsular Pyramid
Ocular associations
• Persistent hyaloid remnants
• Posterior lenticonus
• Persistent hyperplastic primary vitreous
Coronary (supranuclear) cataract
Usually sporadic
Systemic associations
• Fabry disease
• Mannosidosis
Lamellar cataract
Usually dominant inheritance
Hereditary
(usually dominant)
Idiopathic
With ocular anomalies
. PHPV
• Aniridia
• Coloboma
• Microphthalmos
• Buphthalmos
CAUSES OF CATARACT IN UNWELL NEONATE
Intrauterine infections
• Rubella
• Toxoplasmosis
• Cytomegalovirus
• Varicella
Metabolic disorders
• Galactosaemia
• Hypoglycaemia
• Hypocalcaemia
• Lowe syndrome
ETIOLOGY OF PEDIATRIC CATARACTS
EVALUATION OF PEDIATRIC CATARACT
• Family history (autosomal • Ocular examination, including
dominant, X- linked, autosomal – Corneal diameter
recessve) – Iris configuration
• Detailed history of the child's – Anterior chamber depth
growth, development, and – Lens position
systemic disorders – Cataract morphology
• Pediatric physical examination – Posterior segment
– Intraocular pressure
EVALUATION OF PEDIATRIC CATARACT
• Laboratory studies for bilateral cataracts
– Disorders of galactose metabolism: urine for reducing substances;
galactose-1-phosphate uridyltransferase; galactokinase
– Infectious diseases: TORCH and varicella titers, VDRL
– Metabolic diseases: urine amino acids test (Lowe syndrome);
serum calcium (low in hypoparathyroidism), phosphorus (high in
hypoparathyroidism ), glucose (high in diabetes mellitus), and
ferritin (high in hyperferritinemia)
SURGERY FOR PEDIATRIC CATARACT
• Timing of procedure
• Intraocular lens use in children
COMPLICATION OF CATARACT SURGERY IN
PEDIATRIC PATIENT
• postoperative infections and bleeding
• Glaucoma
• (rare) Retinal detachments, macular edema, and
corneal abnormalities
Thank you for your attention!