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Introduction

Ureteropelvic junction obstruction (UPJO) is characterized by


an impaired flow of urine from the renal pelvis to the ureter owing to blockage.
Technetium 99m (99mTc) MAG3 is a method of choice for the detection of urinary
tract obstruction. The morphology of TC-99m MAG3 diuretic renogram drainage
curves can vary between patients. A new measurement is defined which is the
percent of maximal tracer that is still present at 20 minutes (P20). P20 can be
easily abstracted from a standard MAG-3 renogram. The purpose of this study is
to increase the sensitivity of MAG-3 renal scan for UPJO by examining the utility of
alternative measurement P20

MATERIAL AND METHODS:

From May to January 2021, 30 patients with unilateral or bilateral PUJO and
underwent for pyeloplasty. Pre and postoperative MAG-3 renal scans were also
available. After which the software generated 20min/peak ratio and diuretic T1/2
method were compared to see which method is sensitive for symptomatic PUJO.
The data were analyzed by a generalized method using statistical computer
software (SPSS version 20), applying paired t-test and analysis of variance for
multi-group comparisons. Pvalue <0.05 was considered statistically significant.
RESULT:

In this study, 30 patients were included who were diagnosed with PUJO. The study
includes 24 males (80%) and 6 females (20%). The mean age of he patients was 11.71
years with St. Deviation ±10.59. The result shows the tatistical significance study. The
finding of this study confesses the software generated 20min/peak ratio had more
reduction after the surgery. Even the diuretic T/12 also showed the clearance but it was
considered non-significant.

CONCLUSION:

It is concluded that the study finds a positive relationship between the pre and post-
operative pyeloplasty of software generated 20min/peak ratio of renal scans. The
study resulted in a significant p-value <0.05. This means he 20min/peak ratio is more
sensitive than diuretic T1/2
0.7
 
0.6
 
0.5
  Pre_peak_L_K&
POST_PEAK_L_K
0.4
Pre_peak_R_K&Post_peakR_K
0.3
pre_diur_L_K&post_diuratL_K
0.2
 
pre_diurR_K&Post_diaureR_K
0.1

0
correlation
-0.1
 
-0.2

PAIRED SAMPLE CORRELATION


paired sample test
50

40 Mean
Std. Deviation
30 Std. Error Mean
Lower
20
Upper
t
10
df
0 Sig. (2-tailed)
Pair 1 Pair 2 Pair 3 Pair 4
-10
References

 Von Rundstedt FC, Scovell JM, Bian SX, Lee D, Mayer WA, Link RE. Percent of
tracer clearance at 40 minutes in MAG3 renal scans is more sensitive than T1/2 for
symptomatic ureteropelvic junction obstruction. Urology. 2017 May 1;103:245-50.

Islam MW, Hooda MN, Abedin KR, Islam MF, Khan SA, Islam MS, Sultana P,
Bhuiyan AK. Comparison of Renal Function before and after Pyeloplasty
determined by 99m Tc-DTPA Renography. Bangladesh Journal of Urology.
2011;14(1):3-6

Bian SX, Choi JM, Mayer WA, Goh A, Link RE. 2306 P40 PROVIDES VALUABLE
FUNCTIONAL INFORMATION BEFORE AND AFTER SURGERY FOR PROBLEMATIC UPJ
OBSTRUCTION PATIENTS WITH A NORMAL PREOPERATIVE T1/2. The Journal of
Urology. 2011 Apr;185(4S):e924-5.

Sparks S, Viteri B, Sprague BM, Rushton HG, Pohl HG, Majd M. Evaluation of
differential renal function and renographic patterns in patients with dietl crisis.
The Journal of urology. 2013 Feb 1;189(2):684-9

Harvey a. Zeisman, janis p. O'malley, james h. Thrall. Renal scintigraphy in: he


requisites in radiology3rd edition.usa: mosby elsevier, 2006; 8:227 - 230.

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