Zero Lecture

BP607P
Medicinal CHEMISTRY III Practical
Revised Bloom’s Taxonomy
Course Outcomes (CO)

CO1 :: Prepare the various active pharmaceutical compounds

CO2 :: Illustrate the various methods for the purity of pharmaceutical
compounds
CO3 :: Apply various chemical and instrumental methods for analysis
CO4 :: Infer the reaction mechanism for carrying out multi-step synthesis
CO5 :: Analyze the 3D representation of organic molecules
CO6 :: Deduce the Microwave-assisted formation strategies
PROGRAMME OUTCOMES
PO1 : Pharmacy Knowledge: Possess knowledge and comprehension of the core and basic
knowledge associated with the profession of pharmacy, including biomedical sciences;
pharmaceutical sciences; behavioral, social, and administrative pharmacy sciences; and
manufacturing practices.
PO3 : Problem analysis: Utilize the principles of scientific enquiry, thinking analytically,
clearly and critically, while solving problems and making decisions during daily practice.
Find, analyze, evaluate and apply information systematically and shall make defensible
decisions.
PO4 : Modern tool usage: Learn, select, and apply appropriate methods and procedures,
resources, and modern pharmacy-related computing tools with an understanding of the
limitations.
PO6 : Professional Identity: Understand, analyze and communicate the value of their
professional roles in society (e.g. health care professionals, promoters of health, educators,
managers, employers, employees).
PROGRAMME OUTCOMES
• PO9: The Pharmacist and society: Apply reasoning informed by the contextual knowledge to
assess societal, health, safety and legal issues and the consequent responsibilities relevant to the
professional pharmacy practice.
• PO10: Environment and sustainability: Understand the impact of the professional pharmacy
solutions in societal and environmental contexts, and demonstrate the knowledge of, and need
for sustainable development.
• PO11: Life-long learning: Recognize the need for, and have the preparation and ability to
engage in independent and life-long learning in the broadest context of technological change.
Self-assess and use feedback effectively from others to identify learning needs and to satisfy
these needs on an ongoing basis.
PROGRAMME SPECIFIC OUTCOMES

• PSO1: Understand the nature and concepts of Pharmacognosy, Pharmaceutical

Chemistry, Pharmaceutics and Pharmacology.

• PSO2: Perform procedures as per laboratory standards in the areas of

Pharmacognosy, Pharmaceutical chemistry, Pharmaceutics and Pharmacology.

• PSO3: Effectively utilize information, and technology to optimize learning

and patient care.
List of Practicals to be performed
Microwave-based synthesis
• To prepare benzimidazole or its derivatives by microwave irradiation technique
Chemical structure drawing
• To provide the demonstration of ChemSketch software
• To determine the various physiochemical properties of drugs using software
Assay of pharmaceutical compounds
• To determine metronidazole content in its capsules by UV spectrophotometry and
comparing it with the label claim
• To determine chloroquine phosphate content in its tablets by UV spectrophotometry
and comparing it with the label claim
• To perform assay of isonicotinic acid hydrazide
Continued…..
• To perform assay of dapsone
• To perform assay of chlorpheniramine maleate
• To perform the assay of Benzyl penicillin
Preparation of compounds
• To prepare and characterize tolbutamide
• To prepare and characterize heaxmine
• To prepare and characterize triphenyl imidazole
• To synthesize chlorobutanol form acetone and chloroform
• To synthesize sulfanilamide from 4-acetamido benzene sulfonyl chloride
• To synthesize 7-hydroxy-4-methyl coumarin from resorcinol
Course details
• LTP – 0 0 4 [4 Practicals/Week]
• Course Weightage Credits:02
• ATT :4
• CAP : 6
• MTP : 10
• MTP-2 :10
• ETP : 70
BOOKS

Textbooks:
• Vogel's Textbook of Practical Organic Chemistry
by Brian S. Furniss, PEARSON
THANK YOU