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Polycythemia
Polycythemia
2021
Case
Counts
Treatment
n os is
Prog
Po or
Treatment
Interferon alpha
Goal of therapy
CYTO-PV (NEJM 2013)
Phlebotomy +/- cytoreduction
vs
Aspirin Phlebotomy
hct < 0.45 for M& < 0.42 for F
CV risk reduction
Resistant/intolerant to HU? vs
Options:
Antihistamines
Interferon 3mU 3x/wk
Paroxetine 20 mg/d (SSRI)
Psoralen plus UVA light
Avoid heat