Immune system

B & T cells
Chandrak Raghunandan
Immunology
Date:13/09/2022
 Objectives

1 2 3 4
Understanding the Understanding B & Explaining how Giving an overview
branches of the T cells both B & T cell as how both
immunity system activation work branches interact
with another
 Branches of
Immunity
1. Specific (adaptive)
- T-cell
- B-cell
2.Non-specific (innate)
- Dendritic
- Macrophages
- Natural KC
- Neutrophils
- Eosinophils
 ADAPTIVE (SPECIFIC)

Humoral mediated Cell mediated immunity

immunity
 B -cells

• Opsonization
- The process of an antibody binding to a pathogen to contain an infection
- It prevents the spread of infection
- It marks the pathogen for destruction
 B- cell
activation
• Needs to bind to an antigen
• Is stimulated by a helper T-cell

• B-cell can be turn into either

- effector cell
- memory cell
Major Histocompatibility Complex
 T-cells
• Protects the body from inside the cell
4 types of T-cell
• Helper
• Memory
• Suppressor
• Cytotoxic

- CD8+
- CD4+
When T-cells bonds to MHC receptor it activates and proliferates into
effector and memory cells
Activation of T-cell
How does regulatory T-cell work
 What do they do ?
• Anti-inflammatory cytokine release
• Cell lysis if immune cells
• Blocking immune signaling
 Reference
• T cells and B-cell: accessed from; Lymphocyte (genome.gov) on 10/09/2022
• T-cells vs B-cells: accessed from; t cells vs b cells - Bing images on 10/09/2022
• B-activation: accessed from;
B Cell Activation - an overview | ScienceDirect Topics on 10/09/2022
• T-cell activation: accessed from; T-Cell Activation - Immunology - Medbullets
Step 1 on 10/09/2022
• MHC: accessed from;
The major histocompatibility complex and its functions - Immunobiology - NC
BI Bookshelf (nih.gov)
on 10/09/2022
• Adaptive immunity: accessed from;
2.7 Adaptive Immunity – Human Biology (umn.edu) on 10/09/2022