Benign prostatic hyperplasia

impact on partners’ quality of

life
Hor Zheng Han ( S2135895)
Year 2, Master of Surgery

Supervisor: Prof. Ong Teng Aik

Dr. Ahmad Nazran bin Fadzli
Introduction
• Benign prostatic hyperplasia (BPH) is a common condition encountered in aging men
and a common cause of lower urinary tract symptoms.
• Benign prostatic hyperplasia (BPH) refers to the nonmalignant growth or hyperplasia
of prostate tissue and is a common cause of lower urinary tract symptoms in men.
Disease prevalence has been shown to increase with advancing age. 1.
• It is known that men with LUTS have impaired health-related and disease-specific
quality of life, little is known how these LUTS can affect the quality of life of their
partners.

• 1. Claus G Roehrborn. Benign Prostatic Hyperplasia: An Overview – Reviews in Urology, 2005

Research questions
Does BPH patients LUTS affect partners’ quality of life?

Significance of patient’s partner quality of life in Malaysian context?

Relation to severity of patients’ LUTS symptoms .

Objectives

Primary objective: to explore impact of patient lower urinary tract

symptoms on their partners’ quality of life

Secondary objective: to explore the association between severity of

Patients’ lower urinary tract symptoms and partners’ quality of life
Hypothesis
• Null hypothesis
LUTS symptoms of BPH patients have no significant impact on partners’
quality of life.

• Alternate hypothesis
Lower urinary tract symptoms of patients with BPH affect partners’
quality of life.
 Literature
Author
Review
Short title Method Data Comment
H.Sells.J.Donovan et al Partner morbidity in BPH 3 phases questionnaire Phase 1=15 Presence of significant
(BJU 2000) Phase 2=15 morbidity in partners
Phase 3 =
90

Pesach Shvartzman et Effects of prostatic Structured telephone interview = 215 Prostatism has an
al symptoms on spouses’ study ( multiple choice impact on men and
(oxford university press QOL questionnaire) women
2001)

Helen Marklund et at Sleep and partner-specific Descriptive and comparative Random, No significant
Scandinavian 2014 QOL in partners of men Mail structured, self n=131 difference
with LUTS symptoms administered LUTS,
compared with partners questionnaire n=126
of men from general
population

Said Fadel Mishriki Partners agree that the
World J Urol (2010) treatment of LUTS
reduces patients’
bother and improves their
quality of life: prospective
12 years
follow-up study
Assessment included
AUA score, flowrates,QoL and
bother validated self-reported
questionnaires completed by
patients and spouses
219 Partners are
affected by patients’
LUTS, appreciate the
improvement after
treatment and may be
valuable contributors in
assessment.
Author Short title Method Data Comment
Dionisios Symptomatic BPH Structure N=50 Significant morbidity
Mitropoulos et al. impact on partners’ questionnaire in the partners
(European urology quality of life Cohort
2002)
Helen Marklund-Bau QOL questionnaire for two groups: a Reliability group 51 Partners are
et al partners of men with reliability Responsive/ affected by the
Scandinavian 2008 LUTS group; and a evaluation group: 51 patients’ BPO
responsiveness/e symptoms, and it is
valuation group. emotional rather
Test-retest than practical
questionnaire aspects which most
affect them.
Talha Assessment of Quality BPH Patient IPSS N=300 BPH
MÜEZZİNOĞLU et al of Life of Partners specific significantly impairs
Turkiye Klinikleri J Partners of Patients QoL the QoL of female
Med Sci 2010 with Benign Prostate questionnaire. partners. This
Hyperplasia: Does negative impact
Benign Prostate correlates with the
Hyperplasia Disturb IPSS values of BPH
Female Partners? patients.
Methodology
• Study: Cross sectional cohort
• Population: BPH patients’ partner and patients
• Location: University Malaya Medical Center
• Period of study : 2023-2024
• tools: questionnaire
Patients = IPSS
Partners=
Questionnaire for partners of patient with BPH

H. Sells et al. BJU international 2000

Inclusion criteria
• Age : 50-75 years old
• Male patients with BPH
Exclusion criteria
• Patients with or suspected malignancy ( eg prostate carcinoma,
bladder carcinoma)
• Patients on CBD(indwelling catheter) or clean intermittent
catheterization due to neurological condition
• Patients do not have partner
• Patients who are not willing to participate in the study
Progress
• Literature review
• Sample size calculation
• research proposal
Thank you