MYOSITIS

OSSIFICANS
MYOSITIS
OSSIFICANS:
◦ Post traumatic
ossification
◦ Sterner’s tumor
◦ Pseudomalignant
osseous tumor
 MEANING:

Essentially metaplasia of
Characterized by osteoid intramuscular connective
and heterotrophic bone tissue resulting in
formation in soft tissues extraosseous bone
formation
 ETIOLOGY:

Repetitive trauma
Severe injury to Most common in
or strain to
joint children
muscles

High incidence Massage given

seen in patients of after trauma
head injury and aggravates the
paraplegia condition
PATHOPHYSIOLOGY
Soft tissue injury

Haematoma formation

Release of cytokines

Endothelial mesenchymal transition of vascular

endothelial cells

Endothelial derived mesenchymal stem cells give rise to

osteoblasts and chondroblasts resulting in bone formation
 Non hereditary MO

TYPES:

Myositis ossificans
progressiva/ fibrodysplasia
ossificans progressiva
TYPES:
Myositis ossificans
Non hereditary MO
progressiva
◦ Calcifications occur at site of ◦ Rare autosomal dominant disorder
injured muscles ◦ Heterozygous mutation
◦ Most commonly in arms, ◦ Presents with painful lumps and
quadriceps stiffness in joints
◦ Most common in thigh, arm,
intercostal spaces
CLINICAL
FEATURES:
 Pain
 Tenderness
 Swelling
 Decreased range of motion
 Mass increases in size over
months
DIAGNOSIS:
1) X-RAY
2) MRI
3) CT scan
4) Ultrasound
TREATMENT:
◦ Rest and observation
◦ Icing the bump
◦ Physical therapy to maintain active range of motion
◦ Avoid heat and massage
◦ Prophylaxis: NSAIDs and lose dose radiation
◦ If severe, surgical excision of lesion when mature
THANK YOU