PERHITU Farmasi Komunitas

NGAN Program Studi

LARUTA Farmasi
2023
N
 COMMON CONVERSION
The liter basic unit of volume used to measure liquids in
pharmacy practice
1 liter = 1000 mL = 1000 cc
1 galloon = 3.785 mL
1 quart = 946 mL
1 pint = 473 mL
1 fl oz = 30 mL (29,57mL)
The gram basic unit of weight used to weigh solids in
pharmacy practice
One gram is equal to the weight of one mililiter of distilled
water at 4˚C
1 kg = 1000 g
1 g = 1000 mg
1 mg = 1000 mcg
1 lb = 454 g
1 oz = 28,4 g (28,35)
 NO. 1
Using the official formula below, calculate the amount of each
ingredient needed to make 240 mL luquid of peppermint oil .
Peppermint Liquid
Peppermint Oil ...... 100 mL
Peppermint powder .... 10 g
Alcohol ......ad 1000 mL
Membuat larutan pepermint 240 mL :
Pepermint oil = 240mL/1000 mL x 100 mL = 24 mL
Pepermint powder = 240 mL/1000 mL x 10 g = 2,4 g
Alcohol = ad 240 mL
1 oleum menthae pip. dibuat mjd 1000 Aqua menthae pip.
kadar b/v: gram dalam 100mL: 100/1000 x 1 =0,1% b/v
R/ Oleum Rosae 1
Spiritus Fortior 19
terbentuk 20 Spiritus Rosae

R/ Spiritus Rosae 4
Aqua 996
1000 Aqua Rosae
Shg 1 Ol. Rosae bisa membuat=20/4x1000= 5000 Aqua Rosae
kadar b/v: 100/5000 x 1 =0,02% b/v
 NO. 2
If a syrup contains 250 mg of tetracyclin in each 5 mL of the
syrup, how many grams of tetracycline are needed to make four
liters of the syrup ?
Jawab : perbandingan
250 mg/5mL = x/4000 mL
x = 4000 mL/5mL x 250 mg
x = 200.000 mg = 200 g
 NO 3
The strengh of a drug is 5 mg per each mililiter of liquid. How
many mililiters must be administered to give the patient 0.05 g
of the drug ?
Answer : 0,05 g = 50 mg
perbandingan
5 mg/1 mL = 50mg/x
x = 50 mg/5 mg x 1 mL
x = 10 mL
 NO. 4

How many grams of potassium permanganate are needed to

compound the prescription above?
 Ada ad 250
 KMNO4: 0,02/100 x 250 = 0,05 g = 50 mg
 NO. 5
Percent mean part of 100 %. A 5% (W/V) solution contains 5g of
active ingredient per 100 ml of total solution. How many grams of
atropine sulfate are needed to prepare the following prescription?

TIDAK ada ad
atropine 2 %, aqua=100%-2%=98%120 g
2%/98% x 120 g = 2,45 g

Jika ada ad= 2/100 x 120 g =2,4 g

 NO. 6
Pharmacist prepared a suspension containing 5 milion units of
penicillin per 10 mililters. How many units of penicillin will ½
mililter of the suspension contain ?
Answer : perbandingan
5.000.000 units/10 mL = x/0,5 mL
x = 0,5 mL/10 mL X 5.000.000 units
x = 250.000 units
 NO. 7
R/ Ascal 3
Sir Thymi 7
Aqua ad 100 g  tara botol
m.f.solutio
S. 3 dd C I
 
Pro. Ny. Insani
Ascal ( PH V hal 51 ) sinonim = Acetylosalicylicus Calcicus =
Kalsiumasetilsalisilat

Resep Standart Kira-kira 1,2 g kalsiumasetilsalisilat (Ascal)

setara dengan 1 gram asam asetilsalisilat (asetosal). Larutan
kaliumasetilsalisilat harus tiap kali dibuat baru dalam air
dingin. Juga dapat di buat dengan sejumlah yang cukup dari
sama asetilsalisilat yang setelah digilas harus dicampur dengan
1/3 dari beratnya dengan carbonas calcicus (CaCO3),
campuran ini dipirik dengan air dingin yang dibutuhkan dan jika
pembentukan CO2 telah selesai, harus disaring.
 PENGAMBILAN BAHAN :
Ascal =3
Asetosal = 1/1,2 x 3 = 2,5 g
CaCO 3 = 1/3 x 2,5 g = 0,83 g
Sir thymi =7
Aqua ad 100 g

Jika Asetosal 3g, brp ascal yg terbentuk?

1,2/1x 3 g =3,6 g
HITUNG DOSIS  BJ
LARUTAN
Maka dihitung BJ krn sediaan dlm gram namun penggunaan
menggunakan sendok (mL)
BJ larutan= kadar zat kental (syr) dlm larutan
= berat zat kental dibagi jmlh sediaan dikali 100%
Ketentuan:
Jika kadar < 16,67 % BJ: 1g/mL (BJ Aqua)
Jika kadar > 16,67  BJ = 1,3 g/mL (BJ Syrup)
kadar: 7/100 x 100 % = 7 % <16,67% BJ = 1 g/mL
 shg dapat menghitung Dosis Penggunaan
DOSIS ACETOSAL
DL: 500mg-1g/ 1,5 g-3g
DM : 1g / 8g
DP:
1xP: 15mL x1g/mLx 2,5 g = 0,375 g
100 g
1xH: 3x0,375 g = 1,125 g
Dikendaki / Tidak dikehendaki
 NO. 8

R/ Paracetamol 800 mg
Alkohol 10 mL
Sir. Simplex 15
Aqua ad 60
m.f.elixir
S. 3 dd I cth (5 mL)
 
Pro: Dinda (5 tahun)
 PENGAMBILAN BAHAN
Paracetamol = 800 mg
Alkohol = 5 mL
Sir Simplex = 15 g
Air ad 60
BJ=15/60 x 100% = 25% >16,67%BJ=1,3 g/mL
DP = 1 x p =5mLx1,3g/mLx 800mg = 86,67 mg
60g
1 x h = 86,67 mg x 3 = 260,01 mg

DP : DL ?  spt slide 18

DP : DM?  spt slide 18

 NO. 9

R/ Paracetamol 80 mg/ 5 mL
Alkohol 5 mL
Sir. Simplex 15
Aqua ad 60 mL  kalibrasi
m.f.elixir
S. 3 dd II cth 
Pro: Debby ( 8 tahun)
 PENGAMBILAN BAHAN
Paracetamol = 60mL/5 mL x 80mg= 960 mg
Alkohol = 5 mL
Sir Simplex = 15 g
Air ad 60 mL

Dosis Paracetamol 80 mg/ 5 mL, satuan total sediaan

& penggunaan sama
Perlu hitung BJ??
DP : 1 x p = 80 mg x 2x5mL = 160 mg
5mL
1 x h = 160 mg x 3 = 480 mg

DP : DL ?  spt slide 18

DP : DM?  spt slide 18

 NO. 10
R/ Potio Riveri sec. PH V 100
S haustus
Pro: Antoni
Resep Standar Potio Riveri (PHV hal 267)
Asam citrate 5
Air 50
Spir citri 5
Sirup simplex 25
Natr Bicarbonat 6
Air 110
Total: 201
 PENGAMBILAN BAHAN
Asam citrate =100/201 x 5 = 2,5
Air = 100/201 x 50 = 25 mL
Spir citri =100/201 x 15 = 2,5
Sirup simplex = 100/201 x 25 = 12,5
Natr Bicarbonat = 100/201 x 6 = 3
Air = 100/201 x 110 = 55 mL

Jika diminta membuat potio riveri diketahui jmlh bahan asam saja maka
cek dpt daftar penjenuhan di PH V
Asam sitrat 10  12,0 NaHCO3
Asam sitrat 5  ????? NaHCO35/10 x12 = 6
Asam tartrat 10  11,2 NaHCO3
Asam tartrat 8  ????? NaHCO3 8/10x11,2=8,96

10 Kalium karbonat 10,1 asam sitrat

10 Kalium karbonat 10,9 asam tartrat
6 Kalium karbonat  ?????? asam tartrat6/10x10,9=6,54
10 Kalium karbonat 10,9 asam tartrat
4 Kalium karbonat  ?????? asam tartrat4/10x10,9=4,36
 TASK 1

R/ Codein 0,2
Sir. Auranti 15
Aqua ad 100  tara botol
S prn 3 dd cth I

Pro: Ny. Tina

BJ=15/100 x 100%=15 % < 16,67 %BJ: 1g/mL
 TASK 2

R/ Gargarisma Kan Sec. FMS 100

S da cum formula

Pro : Melinda (20 thn)

FMS
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SELAMAT MENGERJAKAN