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Predisposing factors Precipitating factors

1. Family history of thyroid 1. High radiation dose


disease.

Directly damages
thyroid cell

Interfere with mitosis


which affect blood
s u p p l y, o r in d u ce
immune response

Pituitary gland and


thyroid dysfunction

Thyroid stimulating
hormone deficiency
Constant
stimulation
cause the neck
Thyroid stimulates T3 to swell; thus, Wo n ’ t r e l e a s e
neck mass or Hypothyroidism
and T4 TSH
goiter.

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