SKIN CASE 1

A2 GROUP 10
CLINICAL IMPRESSION & DIFFERENTIALS
 Case findings Malignant Melanoma Seborrheic keratosis Benign nevus Non melanoma Skin
cancer
Risk factor: Age Av:65 y/o Middle aged or older Common in all age SCC >50 y
Superficial spreading Congenital or acquired BCC> 50-80 y
melanoma (40-50 y)
Risk factor: Gender Men Both can get it Both SCC & BCC bot M:F::2:1

Risk factor: UV ✅(most imp) ✅ ✅ ✅

RF: Familial history ✅(10-15% cases) ✅(FGRF3) ✅ ✅

Common location Anywhere Mc: Back, abdomen Anywhere Sun exposed areas
Common: Trunk, Least common: Mc in sun exposed areas Typically in lips
extremities extremities, head, neck SCC :lower BCC: upper
Presentation Asymmetry Stuck on verrucous Symmetrical SCC : Scaly, plaque like,
Border irregular plaque Fine border nodular, papillomatous,
Color is not uniform One color and/or verrucous lesion
(Brown to black) < 6mm BCC: Pearly, nodular
Diameter > 6mm Large variant has lesion
Evolving increased risk for Slower than melanoma
Rapid than other melanoma
Melanoma Benign nevus
 Coexisting Malignant melanoma with
seborrheic keratosis

Single 2 × 2 cm asymmetric dark brown and black

plaque with erythematous, uneven border, on Scattered stuck-on verrucous plaques
left upper arm. on back and abdomen.
 Two growth phase
Radial (Irregular plaque)
Vertical (Presents as
nodular)
What is the most important prognostic
factor of melanoma?
 References

https://www.aad.org/public/diseases/skin-cancer/types/common/melanoma/men-50#:~:text=Men%20are%20more%20likely%20to,than%20women%20to%20dev
elop%20melanoma
.

https://www.cancer.org/cancer/melanoma-skin-cancer/about/key-statistics.html#:~:text=The%20risk%20of%20melanoma%20increases,adults%20(especially%20yo
ung%20women)
.

https://emedicine.medscape.com/article/280245-differential

https://www.amboss.com/us/knowledge/Melanoma/

https://www.wikidoc.org/index.php/Melanoma_differential_diagnosis

https://www.ncbi.nlm.nih.gov/books/NBK545285/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577645/#:~:text=Seborrheic%20keratosis%20and%20melanoma%20separately,histologic%20confirmation%20of%
20the%20diagnosis
.

https://www.vucare.com/2018/12/28/seborrheic-keratosis-vs-melanoma/#:~:text=Despite%20their%20appearance%2C%20the%20big,serious%20type%20of%20ski
n%20cancer
.

https://www.medicalnewstoday.com/articles/266748#symptoms

https://my.clevelandclinic.org/health/diseases/21721-seborrheic-keratosis

https://www.ncbi.nlm.nih.gov/books/NBK545285/#:~:text=Although%20seborrheic%20keratosis%20lesions%20are,populations%20with%20lighter%20skin%20tone
s
.