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INTESTINE
INTESTINE
INTESTINE
Presented by
Deepika . R
M . Sc (N) I year
College of nursing
Madras medical college
• INTRODUCTION
• The large intestine is part of the digestive tract.
• The large intestine is approximately 5 feet long, making up one-fifth of
the length of the gastrointestinal (GI) tract.
• The large intestine is responsible for processing indigestible food
material (chyme) after most nutrients are absorbed in the small
intestine.
• The large intestine is composed of 4 parts.
• It includes the cecum and ascending colon, transverse colon, descending
colon, and sigmoid colon.
• The large intestine performs an essential role by absorbing water,
vitamins, and electrolytes from waste material
• Function
• The large intestine has 3 primary functions:
• Absorbing water and electrolytes,
• Producing and absorbing vitamins, and
• Forming and propelling feces toward the rectum for elimination.
• Mechanism
• Motility
• The intestinal wall is made up of multiple layers.
• The 4 layers of the large intestine from the lumen outward are the
• Mucosa,
• Submucosa,
• Muscular layer, and
• Serosa.
• CONT…
• The muscular layer is made up of 2 layers of smooth muscle,
• The inner, circular layer, and
• The outer, longitudinal layer.
• These layers contribute to the motility of the large intestine.
• There are 2 types of motility present in the colon,
• Haustral contraction and
• Mass movement.
• Absorption of Water and Electrolytes
• Absorption of water occurs by osmosis.
• Water diffuses in response to an osmotic gradient established by the
absorption of electrolytes.
• Sodium is actively absorbed in the colon by sodium channels.
• Potassium is either absorbed or secreted depending on the concentration
in the lumen
• Production/Absorption of Vitamins
• The colon also plays a role in providing required vitamins through an
environment that is conducive for bacterial cultivation.
• Cont…
• The colon houses trillions of bacteria that protect our gut and produce
vitamins.
• The bacteria in the colon produce substantial amounts of vitamins by
fermentation.
• Vitamin k and b vitamins, including biotin, are produced by the colonic
bacteria.
• These vitamins are then absorbed into the blood.
• When dietary intake of these vitamins is low in an individual,
• The colon plays a significant role in minimizing vitamin disparity.
• The lower gastrointestinal (GI) tract includes the small and large
intestines
• from the duodenum to anus .The material that
• moves down the lower GI tract consists of food residues,
microorganisms,
• digestive secretions, and mucus. The mixture of these substances
• composes feces
• Disorders of the lower GI tract usually affect
• movement of feces toward the anus, absorption of water and
electrolytes,
• and elimination of dietary wastes.
• IRRITABLE BOWEL SYNDROME
• Irritable bowel syndrome (IBS) is a functional motility disorder
• primarily affecting the colon. It refers to a cluster of
• symptoms that occur despite the absence of an identifiable
• disease process.
• INCIDENCE
• It is estimated that one in five people in the United
• States have IBS (Mayo Clinic, 2008). Women are affected
• more often than men, which suggests a hormonal influence.
• IRRITABLE BOEWL SYNDROME
• In irritable bowel syndrome, the
spastic contractions
• of the bowel are visible in x-ray
contrast studies.
• Etiology
• The cause of IBS is unknown
• Hypersensitivity of the bowel wall that leads to disruption of the normal
function of the intestinal muscles.
• There is a familial predisposition.
• Stress, caffeine, and sensitivity to certain foods
• Dairy and wheat products seem to trigger IBS in some people.
neuroendocrine dysregulation(due to any causes)
Changes in motility
parasympathetic neurotransmitter
• (e.g., acetylcholine) is released, intestinal motility increases
Parasympathetic neuro transmitted
(E.G., Acetylcholine) is released
Diarrhea occur
submucosa into
surrounding tissue.
The disorder is more common in older patients.
ESOPHAGEAL DIVERTICULUM
• SIGNS AND SYMPTOMS:
• Initially be asymptomatic
• Inflammation or infection
• Rectal bleeding.
• Diverticulitis of the Intestine produces
symptoms of diarrhea or constipation,
• Acute left lower abdominal pain,
• Bloating,
• nausea, and
• vomiting.
• Esophageal diverticula
• Produce symptoms of
• Dysphagia,
• Regurgitation,
• Nocturnal cough, and
• Halitosis (bad breath).
• There is a risk of esophageal perforation .
• CONT….
• COMPLICATION:
• Intestinal obstruction or
• By peritonitis if the intestinal wall ruptures.
If bleeding is massive, there will be
hypotension and
• eventual shock.
• DIAGNOSTIC EVALUTION:
• Computed tomography of the abdomen with
colonic contrast.
• Barium enema and
• colonoscopy should be avoided in acute cases
because of the risk of bowel perforation
• Dietary management:
• A high-fiber diet :
• breads and fruits such as
• Apples,
• Seedless berries,
• Peaches, and pears adds fiber.
• High-fiber - vegetables—squash,
broccoli, cabbage, and spinach—and
legumes, including dried beans, peas,
and lentils,
• Provide bulk that decreases constipation
and speeds intestinal transit time.
• Plenty of fluids helps regularity.
• Patients who have recurrent diverticulitis may be instructed to
• Avoid foods:
• Husks, such as peanuts, sunflower seeds, berries with seeds, tomatoes, and
popcorn, as a precaution;
• The husks may get into the diverticulum and irritate it, causing
• Inflammation and eventual diverticulitis.
• Medical management:
• managed conservatively.
• increased fluids and bulk
• laxatives, or stool softeners to control constipation may be all that are needed.
• For diverticulitis, antidiarrheal medication may be prescribed.
• stool softeners to control constipation
• For diverticulitis,
• antidiarrheal medication may be prescribed.
• Mild pain medication-abdominal discomfort in ambulatory patients.
• Outpatient treatment may include clear liquids for 2 to 3 days with oral
antibiotics.
• parenteral antibiotics with intravenous (IV) hydration and bowel rest
• Morphine is acceptable for pain management
• SURGICAL MANAGEMENT :
• surgical removal of the affected part of the colon.(colectomy)
• The Hartmann’s procedure for diverticulitis: primary
• resection for diverticulitis of the colon. The affected segment
• (clamp attached) has been divided at its distal end. In a
• primary anastomosis, the proximal margin (dotted line) is
transected
• and the bowel attached end to end. In a two-stage
procedure,
• a colostomy is constructed at the proximal margin with
• the distal stump oversewn (Hartmann procedure, as shown)
• and the stump is left in the pelvis. The distal stump may be
• brought to the surface as a mucous fistula if there is concern
• about blood supply. The second stage consists of colostomy
• takedown and anastomosis.
• INTESTINAL OBSTRUCTION
• Intestinal obstruction is a sudden or gradual blockage of the intestinal
tract that prevents the
• normal passage of GI contents through the intestines
• Etiology:
• Mechanical obstruction
• Nonmechanical obstruction
• Mechanical obstruction
• blockage of the lumen of the bowel. Examples include
• tumors,
• adhesions,
• CONT……
• strangulated hernia,
• twisting of the bowel (volvulus),
• telescoping of one part of the
• bowel into itself (intussusception),
• barium impaction,
• intestinal parasites, and
• Gallstones
• Abdominal adhesions are a common
cause of intestinal obstruction.
• Three causes of intestinal obstruction.
• A, Intussusception ; Invagination or shortening of
the colon caused by the movement of one
segment of bowel into another.
• B, Volvulus of the sigmoid colon; the twist is
counterclockwise in most cases. Note the
edematous bowel.
• C, Hernia (inguinal). The sac of the hernia is a
continuation of the peritoneum of the abdomen.
The hernial contents are intestine, omentum , or
other abdominal
• contents that pass through the hernial opening
into the hernial sac.
• Nonmechanical obstruction
• Absence of peristalsis.
• Paralytic ileus (failure of forward movement of bowel contents)
• After abdominal surgery, from infection, or as a consequence of
hypokalemia
• Secondary to intestinal thrombus.
• Infections can occur in some pelvic inflammatory diseases or
• Peritonitis,
• In uremia, and
• In heavy-metal poisoning.
• PATHOPHYSIOLOGY:
• Due Mechanical obstruction
• obstruction/Infection occur.
• If fluid or gas accumulate in the intestine
The end result is inflammation of the mucosal lining of the intestinal tract,
•
• causing ulceration, edema, bleeding, and
• fluid and electrolyte loss.
Area affected Mucosa only; usually involves rectum Full thickness of the intestine; most
and proceeds up the colon. common in small intestine.
Signs and Diarrhea, frequently bloody; Fever, malaise, fatigue, weight loss,
symptoms abdominal cramping relieved by intermittent diarrhea, cramping or
defecation; rectal bleeding. steady right lower
quadrant or periumbilical pain,
postprandial bloating.
Complication Massive hemorrhage; hypovolemia, toxic Fistulas, anal fissures, perianal disease, bowel
megacolon (rapid dilation of obstruction or perforation
the intestines), cancer of the colon.
• Signs and Symptoms
• Patients with IBD have attacks of diarrhea that may be bloody and
contain mucus; abdominal
• pain with cramping; malaise; fever; and weight loss.
• Slow bleeding and oozing will show a black, tarry stool. If
• diarrhea is frequent, the blood may be more reddish.
• Others have serious intestinal
• hemorrhage with fluid and electrolyte imbalances.
• Opioids and Anticholinergic Medications
• opioid medications or anticholinergic medications should be
• avoided if there is fever, leukocytosis, or worsening symptoms because
these medications will further reduce the tone of the colon
• Diagnosis
• based on the patient's medical history and symptoms Colonoscopy,
flexible sigmoidoscopy, mucosal biopsy, barium enema, and stool analysis
may be
• performed to confirm the diagnosis.
• Treatment
• Treatment for UC and Crohn disease varies according to severity and
frequency of symptoms.
• administration of antidiarrheal drugs,
• Long term sulfasalazine therapy, and
• medications to relieve abdominal cramps.
• Budesonide (Entocort) is used to help control disease in the ileum.
Patients with
• advanced disease who are not surgical candidates may be given
azathioprine, 6-mercaptopurine,methotrexate, levamisole, or
cyclosporine to help control the disease
• Infliximab (Remicade), a monoclonal antibody against tumor necrosis
factor, has greater than 80% response rate for Crohn disease, but only
about a 50% success rate with UC.
• The drug is extremely expensive and is given IV by a set protocol.
• Certolizumab pegol (Cimzia) is a drug for
• patients with moderate to severe Crohn disease who have not
responded to conventional treatments.
• Corticosteroids are used for moderate to severe cases to decrease the
inflammation.
• During acute attacks, fluid replacement may be necessary.
• Blood transfusion are given when anemia is present. Oral 5-
aminosalicylic acid (5-ASA) derivatives, such as olsalazine sodium
(Dipentum), are useful for those patients who cannot tolerate
sulfasalazine.
• THE RECOMMENDED DIET:
consists of low-fat,
• low-fiber foods that are high in protein and calories.
• Small frequent feedings are best.
• Lactose avoidance helps some patients
• SURGICAL INTERVENTION:
• Proctocolectomy, and creating an ileostomy.
• A patient with uc may be a candidate for an ileal reservoir (kock pouch) or
an ileoanal
• Anastomosis rather than a standard ileostomy
• The patient uses a catheter to empty the reservoir after the Kock procedure
• Nursing Management
• Assessment (Data Collection)
• A complete health assessment is performed with particular attention to
nutritional, fluid, and
• electrolyte status. A thorough abdominal assessment is performed,
identifying pain location.
• Nursing diagnosis and planning
• Problem statements/nursing diagnoses might include:
• Acute or chronic pain due to intestinal inflammation.
• Fluid volume deficit due to diarrhea fluid loss.
• Implementation and evaluation
• For an acute attack of IBD, care includes monitoring the number and character of
stools, periodic
• Auscultation of bowel sounds, measurement of intake and output, and daily
weight measurement.
• Check for signs of internal bleeding and monitor laboratory data for evidence of
electrolyte
• Imbalances and anemia. Indicators of successful therapy include a decrease in
abdominal cramping
• And discomfort and return of typical bowel pattern.
• Risk Factors for Colorectal Cancer:
• Increasing age.
• Family history of colon cancer or polyps
• Previous colon cancer or adenomatous polyps
• High consumption of alcohol
• Cigarette smoking
• Obesity
• History of gastrectomy
• History of inflammatory bowel disease
• High-fat, high-protein (with high intake of beef), low-fiber diet
• Genital cancer ( eg , endometrial cancer, ovarian cancer) or
• Breast cancer (in women).
• Cancer of the Colon
• Cancer of the large intestine, also called colorectal cancer, is the third most
common malignancy in both men and women in the United States
• Approximately 93,090 colorectal cancer cases were expected to occur in
2015 (American Cancer Society, 2015).
• Colorectal cancer is one of the most preventable and curable of all cancers
if it is found in the early stages, and
• mortality rates have fallen over the last 30 years as detection has become
easier.
• Healthy People 2020
• objectives include the reduction of deaths by colorectal cancer and a
decrease in the incidence of
• invasive colorectal cancer.
• Colorectal cancer incidence
• Colorectal cancer incidence is highest in African American men and women.
Mortality rates in
• African Americans also are higher than in the white population. It is not
certain whether this is
• Because of limited access to health care or other reasons.
• Etiology
• The cause of colorectal cancer has not been established but is generally
believed to be a mutation of a naturally occurring process of colon tissue
repair and replacement. Other risk
• factors are smoking, alcohol consumption, physical inactivity, obesity, and a
diet high in saturated
• fat and/or red meat, as well as inadequate intake of fruits and vegetables
• Other risk factors are
• smoking,
• alcohol consumption,
• physical inactivity,
• obesity, and
• a diet high in saturated
• fat and/or red meat, as well as inadequate intake of fruits and vegetables
• The Colon and Conjugated Linoleic Acid
• In research studies with animals, conjugated linoleic acid (CLA) was found
to have a protective
• effect against inflammation-induced colon cancer
• PATHOPHYSIOLOGY:
• The cancerous tumor tissue may be polypoid, protruding into the bowel
lumen
• The tumor may spread into adjacent structure or via the lymphatics
• or the bloodstream.
• Any change in bowel habits, either diarrhea or constipation, could be a
sign of colon cancer
• (American Cancer Society, 2015a).
• Other symptoms include red blood in the stool, black tarry stools,
change in stool shape
• (ribbonlike stool), abdominal distention without weight gain, sensation
of incomplete evacuation
• after a bowel movement, and anemia resulting from intestinal bleeding
• DIAGNOSIS:
• Screening tests include an annual stool guaiac test or fecal
immunochemical test or stool DNA test
• double contrast barium
• x-ray every 5 years, or CT colonography (virtual colonoscopy) every 5
years. Colonoscopy is
• recommended if any of the screening tests are positive (American
Cancer Society, 2015a). If
• adenomatous polyps are discovered early and removed, colon cancer
could be prevented
• Transrectal ultrasound may
• Be used to determine the extent of a small rectal lesion.
Carcinoembryonic antigen (CEA) is elevated
• In 70% of patients with colorectal cancer, but because it is nonspecific to
this type of cancer,
• Treatment:
• Treatment of colorectal cancer usually involves surgical removal of the
affected portion of the Intestine.
• Reconnection of the remaining intestine portions (anastomosis) is done
if the lesion is
• Most tumors are resected with an open approach, but laparoscopic surgery is
an option for a
• small, localized tumor.
• Colectomy or hemicolectomy.
• Colectomy is the removal of the diseased portion of the colon. The remaining
ends of the colon are
• reattached (anastomosed). Hemicolectomy is removal of one half of the colon.
• Abdominoperineal resection.
• Abdominal resection is performed for cancer in the rectum or low sigmoid
colon. It is a very
• extensive surgical procedure in which part of the colon and the entire rectum,
anus, and regional
• lymph nodes are removed.
• Examples of areas where cancer can occur,
the
• Area that is removed, and how the
anastomosis is performed
• Cecum and lower
• Ascending colon
• Descending colon
• And upper sigmoid
• Low sigmoid and
• Upper rectum
• Rectal sigmoid resection
• Staging of Colorectal Cancer:
• Dukes’ Classification–Modified Staging System
• Class A: Tumor limited to muscular mucosa and
• submucosa
• Class B1: Tumor extends into mucosa
• Class B2: Tumor extends through entire bowel wall into
• serosa or pericolic fat, no nodal involvement
• Class C1: Positive nodes, tumor is limited to bowel wall
• Class C2: Positive nodes, tumor extends through entire
• bowel wall
• CONT…..
• Class D: Advanced and metastasis to liver, lung, or bone
• Another staging system, the TNM (tumor, nodal involvement,
• metastasis) classification, may be used to describe
• the anatomic extent of the primary tumor, depending on:
• Size, invasion depth, and surface spread
• Extent of nodal involvement
• Presence or absence of metastasis
• The higher the score in each category, the worse the
• disease and prognosis.
• Diagnosis
• Nursing Diagnoses
• Based on the assessment data, the major nursing diagnoses
• May include the following:
• Imbalanced nutrition, less than body requirements , Related to nausea
and anorexia
• Risk for deficient fluid volume related to vomiting and Dehydration
• Anxiety related to impending surgery and the diagnosis Of cancer
• Risk for ineffective therapeutic regimen management
• Related to knowledge deficit concerning the diagnosis,
• The surgical procedure, and self-care after discharge
• CONT….
• Impaired skin integrity related to the surgical incisions (abdominal and
perianal), the formation of a stoma, and frequent fecal contamination
of peristomal skin
• Disturbed body image related to colostomy
• Ineffective sexuality patterns related to presence of ostomy and
changes in body image and self-concept
• Planning and Goals
• The major goals for the patient may include attainment of optimal level
of nutrition;
• Maintenance of fluid and electrolyte balance;
• Reduction of anxiety;
• Learning about the diagnosis, surgical procedure, and self-care after
discharge;
• Maintenance of optimal tissue healing;
• Protection of peristomal skin;
• Learning how to irrigate the colostomy
• Nursing Interventions
• Preparing the Patient for Surgery
• The patient awaiting surgery for colorectal cancer has many
• concerns, needs, and fears.
• Providing Emotional Support
• Patients anticipating bowel surgery for colorectal cancer
• may be very anxious. They may grieve about the diagnosis,
• the impending surgery, and possible permanent
• colostomy.
• Providing Postoperative Care
• Postoperative nursing care for patients undergoing colon resection
• or colostomy is similar to nursing care for any abdominal
• surgery patient (see Chapter 20), including pain
• management during the immediate postoperative period
• Maintaining Optimal Nutrition
• The nurse teaches all patients undergoing surgery for colorectal
• cancer about the health benefits to be derived
• from consuming a healthy diet.
• Providing Wound Care
• The nurse frequently examines the abdominal dressing during
• the first 24 hours after surgery to detect signs of hemorrhage.
• Monitoring and Managing Complications
• The patient is observed for signs and symptoms of complications.
• It is important to frequently assess the abdomen,
• including bowel sounds and abdominal girth, to detect
• bowel obstruction.
• Removing and Applying the Colostomy Appliance
• The colostomy begins to function 3 to 6 days after surgery.
• The nurse manages the colostomy and teaches the patient
• about its care until the patient can take over its management.
• Irrigating the Colostomy
• The purpose of irrigating a colostomy is to empty the colon
• of gas, mucus, and feces so that the patient can go about social
• and business activities without fear of fecal drainage.
• Supporting a Positive Body Image
• The patient is encouraged to verbalize feelings and concerns
• about altered body image and to discuss the surgery
• and the stoma (if one was created).
• Discussing Sexuality Issues
• The nurse encourages the patient to discuss feelings about
• sexuality and sexual function.
• Promoting Home and Community-Based Care
• TEACHING PATIENTS SELF-CARE. Patient education and
• discharge planning require the combined efforts of the
• physician, nurse, WOC nurse, social worker, and dietitian.
• Patients are given specific information, individualized
• to their needs, about ostomy care and signs and
• symptoms of potential complications.
• PLACEMENT OF PERMANENT
COLOSTOMIES. THE NATURE
• of the discharge varies with the site. Shaded
areas show sections
• of bowel removed. A, With a sigmoid
colostomy, the feces
• are formed. B, With a descending colostomy,
the feces are semi formed.
• C, With a transverse colostomy, the feces are
unformed.
• D, With an ascending colostomy, the feces
are fluid.
• Gastric Common
causes of
peritonitis . ulcer
• Appendicitis
• Duodenal ulcer
• Inflammatory
• bowel disease
• Diverticulitis
• of sigmoid