Tablet- Equipment and Tablet tooling

Assignment of

Industrial Pharmacy-I
Session 2021-22

Supervisors:
Submitted by –
Dr. Ashish Jain Mr. Suyash Jain
ROLL NO:– Y19150062
Dr. Nishi Modi

Department Of Pharmaceutical Sciences

Dr. Harisingh Gour Vishwavidyalaya, Sagar (M.P.)
( A Central University )
 Equipments
After the preparation of granules (in case of wet granulation) or sized
slugs (in case of dry granulation) or mixing of ingredients (in case of
direct compression), they are compressed to get the final product.
The compression is done either by

single punch machine (stamping press)

or by

multi-station machine (rotary press)

 Single Stationary/Single Punch Press

presents a single punch press with one die and one pair of
punches
 Components of a Single Station Press

1.Hopper.
2.Die Cavity
3.Punches
4.Cam Truck
5.Tablet Adjuster
6.Ejection Adjuster
 Advantages of a Single Station Press

1) The structure of a single punch is balanced and small.

2) It can be easily operated at a high utilisation ratio.
3) It can also produce odd-shaped products having a
diameter of up to 20mm.
4) It is suitable for development of tablets and small batch
production.
5) It reduces weight variations between tablets by utilising a
high amount of pressure.
6) It also maintains a low noise level during operation.
 Multi-Station/Rotary Press

the head of the tablet machine that holds the upper punches, dies, and
lower punches in place, rotates.
As the head rotates, the punches are guided up and down by fixed cam
tracks, which control the sequence of filling, compression, and ejection.
The head portions holding the upper and lower punches are called the
upper and lower turrets, respectively, and the portion holding the dies is
the die table.
 Advantages of a Multi-Station Press

1) 1) This operation is cheaper, less labour intensive, and

involves high productivity.
2) 2) The process is time saving and is capable of meeting
high demand of tablet dosage form.
3) 3) A moving feeder is required for managing the powder
filled cavity automatically.
4) 4) Rotary press involves minimum wastage of valuable
formulation in non-specific tablets.
5) 5) Both weight and hardness can be controlled
independently by the rotary press.
 Tablet Tooling

Most commonly the tablets are

manufactured in circular, oval, and oblong
shape. However, they can also have
triangular and diamond shapes. When
viewed sideways, the tablets appear flat or
convex and with or without bevelled
edges. Break marks, symbols, or other
markings may also be present on tablets.
Break marks or break lines are provided so
that tablets can be broken in a controlled
manner to ensure reproducible doses.
Markings which help in identifying a
preparation are embossed (raised on the
tablet surface) and debossed (indented
into the tablet).
 Types of Tooling

A tooling set including the die and its connected punches are of two types:
1) "B" Type: A punch barrel having a diameter of 0.750 inches (19mm) is utilised in
this configuration type. Two types of dies having different die sizes can be used
in B type tooling:
i)The "B" dies of 1.1875 inches (30.16mm) diameter are suitable for all tablet sizes
up to the maximum for the "B" punches.
ii) The smaller "BB" dies or small "B" die of 0.945 inches (24mm) diameter are
suitable for tablets of 9-11mm diameter.

2) "D" Type: The minimum barrel diameter of this type is 1 inch (25.4mm) and a die
diameter is 1.500 inches (38.10mm). Therefore, it is suitable for tablets having
maximum diameter or maximum length of 25.4mm.

Two other types of tooling are also present:

1) "BB" type, and 2) "DB" type.
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