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THE

MENSTRUAL
CYCLE
IRENE C. LABOG, RN, LPT
Teacher in Biological Science
THE
MENSTRUAL
CYCLE
OBJECTIVE:

1. Identify hormones that


triggers menstruation.

2. Describe what happens in


each stage of menstrual cycle.
WHAT IS THE MENSTRUAL CYCLE?
 Theprocess in which females ripen or release
one mature egg.
PHYSIOLOGY OF MENSTRUATION
THE OVARIES...

 1. Hypothalamus releases GnRH

 2. Release of GnRH triggers APG to


release FSH and LH
 FSH- responsible for the maturation
of ovum and follicle formation.
 Causes an increase in estrogen

 LH – triggers ovulation and growth


of uterine lining
 Upsurge in LH causes the release
of prostaglandin
 Increase in LH causes production
of Lutein (bright yellow fluid, HIGH
IN PROGESTERONE) that will fill
the empty pit
 Follicle becomes “CORPUS
LUTEUM”
 if fertilization occurs, ovum
implants at the uterus, corpus
luteum stays inside the ovaries
until 16-20 weeks; trophoblast
begin secreting HCG
 without fertilization, ovum
atrophies after 4-5 days, CL
remains for only 8-10 days.
 CL replaced by white

fibrous tissue, CL becomes


“CORPUS ALBICANS”
PHYSIOLOGY OF MENSTRUATION
THE UTERUS...
1st PHASE: PROLIFERATIVE

 High levels of estrogen causes


thickening and proliferation of
endometrium

 LH is increased, Estrogen is
increased
2nd PHASE: SECRETORY

Increased levels of progesterone


causes glands at endometrium to
become cork screw like or twisted in
appearance and dilated with
quantities of glycogen and mucin

 Increased in capillaries making


endometrium appear like a
rich spongy velvet

 Increased Progesterone
3RD PHASE: ISCHEMIC

 Decreased estrogen and


progesterone levels causes
the degeneration of the
endometrium

 Capillaries
rupture,
endometrium sloughs off
PHYSIOLOGY OF MENSTRUATION
THE CERVIX...
1st half of the cycle
 Hormones decreased
 Mucus thick and scanty
 Poor sperm survival

Ovulation
 Estrogen is increased
 Cervical mucus thin and copious
 Excellent sperm survival

2nd half
 Decreased progesterone level
 Mucus is thick
 Poor sperm survival

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