The Biotechnology and

Pharmaceutical Industry Challenges

 Compete Globally
 Speed up Development
 Increase Quality
 Reduce Costs
The Biotechnology and
Pharmaceutical Industry Challenges

New product development must be executed

faster, cheaper and better than ever before

At the same time, the number of new

candidate products increases faster than
traditional lab bench technology can
screen
The Biotechnology and
Pharmaceutical Industry Challenges

How can the biotechnology/pharmaceutical

professional accelerate candidate product
screening, and improve scale-up, to establish
ever more reliable, validated production
systems?
The Solution:
Membrane Technology
 Purification, separation and
concentration objectives are
performed quickly and reliably

 These methods are

completely compatible with
lab-to-plant techniques

 Our technology ensures

optimum screening, as
well as reliable and
efficient production
systems
Bio/Pharm Membrane Technology

Spiral-wound membranes
 Developed and designed
specifically for the biotechnology
and pharmaceutical industries
 An elegant, flexible and
scalable approach, from lab
bench to full production
 How It Works

LARGE
POLYSACCHARIDES
 Utilizes reverse PROTEINS
ENZYMES
osmosis,
nanofiltration,
ultrafiltration and SMALL
microfiltration POLYSACCHARIDES
ANTIBIOTICS
technology to filter DIVALENT SALTS
and separate by
molecular weight,
charge, physical size
and hydrophilicity
MONOVALENT SALTS
ANTIBIOTICS
 How It Works

LARGE
POLYSACCHARIDES
 Engineered for PROTEINS
ENZYMES
extreme conditions of
pH, temperature,
viscosity and other SMALL
process conditions POLYSACCHARIDES
ANTIBIOTICS
DIVALENT SALTS

MONOVALENT SALTS
ANTIBIOTICS
 Membrane
Capabilities

LARGE
POLYSACCHARIDES

 Separate and PROTEINS

ENZYMES
concentrate drugs,
intermediates, fine
chemicals and heat SMALL
POLYSACCHARIDES
sensitive compounds
ANTIBIOTICS
DIVALENT SALTS
 Purify drugs and fine
chemicals

 Recover non-reacted
MONOVALENT SALTS
components ANTIBIOTICS
 Membrane
Capabilities

LARGE
POLYSACCHARIDES

 Recover solvents PROTEINS

ENZYMES

 Dewater reaction
streams SMALL
POLYSACCHARIDES

 Produce USP and ANTIBIOTICS

DIVALENT SALTS
WFI grade water

 Custom fit to your

latest application
MONOVALENT SALTS
ANTIBIOTICS
BioPharmaceutical Applications

 WFI  Concentration and

Purification of
 Serum Filtration products such as:
 Enzymes
 Cell Harvest  Antibiotics
 Amino acids
 Lysate Clarification  Proteins and
r-proteins
 Sterilization  Polysaccharides
 Imaging agents