ISOTONICITY REVIEW

PROBLEMS
Prepared by : Philipo Raphael
6/7/2023
QUESTION
1% of boric acid solution has a freezing point depression of 0.29 °
C ,what is the percentage concentration of boric acid required to make
this solution isotonic ?
SOLUTION 1
QUESTION 2
1 % of silver nitrate has freezing point depression of 0.19 ° C what is
the percentage concentration of silver nitrate required to make this
solution isotonic ?
SOLUTION
QUESTION 3
The freezing point of a 5 % solution of boric acid is -1.55°,how many
grams of boric acid should be used in preparing 100 ml of an isotonic
solution?
SOLUTION 3
QUESTION 4
Compound the following prescription using White- Vincent method
Rx
Ephedrine sulfate 1 %
Sodium chloride q.s
Isotonic solution 40 ml
Sig gtt ii each nostril q6h

How much NaCl would be neede to render this solution isotonic ?

SOLUTION 4
QUESTION 5
Compound the following prescription using White- Vincent method
Rx
Phenlyephrine HCL 0.5
Boric acid q.s
Water q.s 50 ml
Sig UD
Make isotonic
How much NaCl would be neede to render this solution isotonic ?
SOLUTION 5
QUESTION 6
How much of NaCl is required to render 100 ml of a 2 % solution of
epinephrine bitartrate isotonic with tears ?
SOLUTION 6
QUESTION 7
Freezing point depression of 1 % pilocarpine nitrate is 0.14 ° C ,
calculate the volume of iso-osmotic solution produced by 1 gram of
pilocarpine nitrate by U.S.P method
SOLUTION 7
END