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Gastrointestinal System Block: Case 5A
Gastrointestinal System Block: Case 5A
CASE 5A
DIVERTICULAR DISEASE
DIVERTICULAR DISEASE
Higher incidence in age >60 years Only 20% develops symptomatic disease Male tends to present in younger age Two types of diverticula
True diverticula
saclike herniation of entire bowel wall
Mostly affect the sigmoid colon, associated with high pressure zone and stool retention Diverticulitis : inflammation of diverticula, associated with fecalith, may lead to perforation or bleeding
Harrisons Principle of Medicine 17th ed Vol I
DIVERTICULAR DISEASE
CLINICAL PRESENTATION
BLEEDING
Only 20% pts of diverticulitis has GI bleeding Self-limited and stops with bowel rest Lifetime risk of rebleeding is 25% Diagnosed and managed by colonoscopy and angiography Mesenteric angiography con localize and occlude 80% cases Segmental resection may eliminate the risk of further bleeding advantageous in patient with chronic blood thinner Harrisons Principle of Medicine
17th ed Vol I
CLINICAL PRESENTATION
DIVERTICULITIS
Best diagnosed by CT : sigmoid diverticula, thickened colon wall >4mm, inflammation Must be distinguished from : IBS, Ovarian Cyst, Endometriosis, Acute Aooendicitis, Pelvic Inflammatory disease, Sigmoid malignancy Barium enema should not be performed in acute setting
Harrisons Principle of Medicine 17th ed Vol I
HINCHEY CLASSIFICATION
MANAGEMENT
MEDICAL MANAGEMENT
Asymptomatic : diet alteration to eat fiberenriched diet, supplementary fiber, avoid nuts and popcorn Simptomatic
Antibiotic : Trimethoprim/Sulfamethoxazole or Ciprofloxacin and Metronidazole. +Ampicillin for non responder. 3rd gen penicillin may be effective. All antibiotics are given for 7-10 days Bowel rest and diet limitation
Harrisons Principle of Medicine 17th ed Vol I
MANAGEMENT
SURGICAL MANAGEMENT
Removal of diseased sigmoid rectosigmoid juntion Mostly done by Hartmaan method Can be open sigmoid resection or laparoscopic sigmoid resection Preoperative risk factors influencing post-operative mortality rates Surgical therapy offered to pts with 2 documented attacks of diverticulitis requiring hospitalization Younger pts should not wait for 2 attacks Goal : controlling sepsis, eliminating complication, restoring intestinal continuity, minimizing morbidity, length of hospitalization Harrisons Principle of Medicine
17th ed Vol I
MANAGEMENT
MANAGEMENT
PROGNOSIS
Reccurence in 10% patient post-operative
Inadequate surgical resection retained diseased segmental IBS initial symptoms