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Asr 701 2022
Asr 701 2022
Research Methodology I
09/03/2023
https://www.youtube.com/watch?v=zJ8Vfx4721M&t=211s
https://www.youtube.com/watch?v=rT9o2c11Epg
https://www.youtube.com/watch?v=Ga7w-czB7lo
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https://www.youtube.com/watch?v=0JzLV5i6D-Q&t=17s
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Course Contents
1. Philosophy of Science
2. Literature Review
3. Inventory Review
4. Inventory of Questions
5. Research Objectives-Dr. Hina Siddiqui
6. Research Hypothesis- Dr. Hina Siddiqui
7. Types of Research Methods
8. Research Phases- Dr. Hina Siddiqui
9. Designing an investigation
10. Qualitative and quantitative Approaches
11. Design of Experiment
12. Identification of Available Technologies and Expertise
13. Research Proposal- Dr. Hina Siddiqui
09/03/2023
What is Research?
• A systematic means of problem solving
(Tuckman 1978)
• 5 key characteristics:
What is Research?
Publish Formulate a
Findings Question
Research Process
Interpret Select an Appropriate
Findings Research Design
Collect Relevant
Data
Research Process
OBSERVATION
Broad area of
research interest
identified
PROBLEM THEORETICAL
DEFINITION FRAMEWORK
HYPOTHESES
Research Variables clearly GENERATION
problem identified and
delineated labeled
SCIENTIFIC
RESEARCH
DESIGN
PRELIMINARY DATA
GATHERING DEDUCTION
Interviewing & Hypotheses DATA COLLECTION,
Literature Survey substantiated? ANALYSIS AND
Research questions INTERPRETATION
answered
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Research Methodology:
An Introduction
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MOTIVATION IN RESEARCH
• Desire to get a research degree along with its
consequential benefits;
• Desire to face the challenge in solving the
unsolved problems, i.e., concern over practical
problems initiates research;
• Desire to get intellectual joy of doing some
creative work;
• Desire to be of service to society;
• Desire to get respectability.
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RESEARCH APPROACHES
• Quantitative/Qualitative
• Applied/Basic
• Deductive/Inductive
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QUANTITATIVE/QUALITATIVE RESEARCH
Quantitative Qualitative
The emphasis of Quantitative Qualitative research is more
research is on collecting and subjective in nature than
analysing numerical data; it Quantitative research and involves
concentrates on measuring the examining and reflecting on the less
scale, range, frequency etc. of tangible aspects of a research
phenomena. subject, e.g. values, attitudes,
perceptions.
This type of research, although Although this type of research can
harder to design initially, is usually be easier to start, it can be often
highly detailed and structured and difficult to interpret and present the
results can be easily collated and findings; the findings can also be
presented statistically. challenged more easily.
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Research types
Basic Applied
Theoretical? Quick Answers?
More Invasive? Less Invasive?
Laboratory Based? Field Based?
Tightly Controlled? Loosely Controlled?
Internal Validity?
Lacks External Validity? Externally Valid?
>
Focus on Mechanism Focus on Effect
More Reductionist Less Reductionist.
Research Continuum
Basic Applied
e.g.
Does Caffeine Ingestion
Improve Athletic
Performance?
Research Continuum
Basic Applied
e.g. e.g.
Does Caffeine Ingestion Does Caffeine Ingestion
Improve Ca2+ binding Improve Athletic
with troponin? Performance?
-Would this Facilitate
Acto-Myosin Coupling?
-Would this aid
contraction?
Research Continuum
Basic Applied
e.g. e.g.
Does Caffeine Ingestion Does Caffeine Ingestion
Inhibit Glycogen Improve Athletic
Phosphorylase? Performance?
Does Caffeine Ingestion
Increase Lipid
Metabolism?
-Would this Spare
Endogenous Glycogen?
Research Continuum
Basic Applied
e.g. e.g.
Does Caffeine Does Caffeine Ingestion
Ingestion Stimulate the Improve Athletic
CNS? Performance?
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Basic
Applied
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Structure of Research
The "hourglass" notion of research
begin with broad questions
narrow down, focus in
operationalize
OBSERVE
analyze data
reach conclusions
generalize back to questions
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Deduction and Induction
Deduction
Induction
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Inductive research approach
When there is little to no existing literature on a topic, it is common to perform inductive
research because there is no theory to test. The inductive approach consists of three stages:
Observation
A low-cost airline flight is delayed
Elephants depend on water to exist
Observe a pattern
Another 20 flights from low-cost airlines are delayed
All observed animals depend on water to exist
Develop a theory
Low cost airlines always have delays
All biological life depends on water to exist
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Reference: https://www.scribbr.com/methodology/inductive-deductive-reasoning/
• Limitations of an inductive approach
• A conclusion drawn on the basis of an inductive
method can never be proven, but it can be
invalidated.
• Example
You observe 1000 flights from low-cost airlines. All of
them experience a delay, which is in line with your
theory. However, you can never prove that flight
1001 will also be delayed. Still, the larger your
dataset, the more reliable the conclusion.
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Reference: https://www.scribbr.com/methodology/inductive-deductive-reasoning/
Deductive research approach
When conducting deductive research, you always start with a theory (the result of inductive
research). Reasoning deductively means testing these theories. If there is no theory yet, you
cannot conduct deductive research.
Analyse the results: does the data reject or support the hypothesis?
5 out of 100 flights of low-cost airlines are not delayed = reject hypothesis
All land mammal species depend on water = support hypothesis
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Reference: https://www.scribbr.com/methodology/inductive-deductive-reasoning/
Writing A Proper Hypothesis
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The hypothesis is the foundation of the
research
• The development of a hypothesis is the first step
in designing and conducting research
• Is valuable because:
▫ States the relationship between the all of your variables to
study
You are ALWAYS testing to find relationships
▫ Explains why these occur
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A hypothesis must satisfy the following
requirements…
• Be expressed in a declarative statement
• Postulate a relationship between variables
• Reflect a theory which will guide the research
• Be brief and concise
• Be testable and/or provable
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Parts of the Hypothesis Statement
• Independent Variable:
The condition be studied. It is controlled by the
experimenter.
ex. Water
• Dependent Variable:
The condition affected by the independent variable. It
can’t be controlled by the experimenter.
ex. Plant Growth
• Control:
The condition that is represented in a normal situation.
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Writing A Proper Hypothesis
Using the “If / Then”
Method
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Steps to Writing the “If” section of your Hypothesis
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Writing the “Then” section of your
Hypothesis
• Write the word then (following the “if” section)
• Make a comment on the relationship between
those two variables.
Ex. If section:
If water is related to plant growth,
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RESEARCH QUESTION
A research question is the question that the
research project sets out to answer.
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Origins of a Research Question
• Careful Observation of People
• Application of New Technology
• The Annoyance Principle
• Build on Experience
• Scientific Communications
– Skeptical Attitude (questioning peers)
09/03/2023 37
Characteristics of a good research
question
• FINER
– Feasible
• Adequate numbers of subjects?
• Adequate technical expertise?
• Affordable in time and money?
• Is it possible to measure or manipulate the variables?
– Interesting
• To the investigator?
– Novel
• To the field?
– Ethical
• Potential harm to subjects?
• Potential breech of subject confidentiality?
– Relevant
• To scientific knowledge/theory?
• To organizational, health or social management and policy?
• To individual welfare?
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Hypotheses
• Examples
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Hypotheses should be developed
before data are collected.
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Hypotheses and Research
Questions
Predicting functional relationships
between variables
Definition:
• Null hypothesis
Symbol = Ho or H0
• Experimental hypothesis
Symbol = H1, Ha, etc.
nondirectional (two-way)
directional (one-way)
• Research Question
Symbol = RQ or R
Null Hypothesis
• Null hypothesis:
– Ho: High exposure to violent video games does not produce
more antisocial behavior in elementary school children than
low exposure.
• Non directional hypothesis:
– H1: Japanese and American supervisors will differ significantly
in their use of threats as a compliance gaining strategy.
• Directional hypothesis
– Ha: Deaf children whose parents are deaf will acquire
language faster than deaf children whose parents are not
deaf.
Phrasing hypotheses and research
questions
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Phases/stages of Research
• Idea-generating phase
• Problem-definition phase
• Procedures-design phase
• Observation phase
• Data-analysis phase
• Interpretation phase
• Communication phase
https://www.scribbr.com/methodology/rese
arch-design
/
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51
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Problem/Question/idea
• Develop a question or problem or idea that can
be solved through experimentation.
• The scientific method starts when you ask a
question about something that you observe:
How, What, When, Who, Which, Why, or Where?
• And, in order for the scientific method to answer
the question it must be about something that you
can measure, preferably with a number.
09/03/2023 53
Problem/Question/idea
• The starting point of most new research is to
formulate a general question about an area
of research and begin the process of defining
it. This initial question can be very broad, as
the later research, observation and narrowing
down will hone it into a testable hypothesis.
09/03/2023 54
Do Background Research
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Narrowing Down
• The research stage, through a process of elimination,
will narrow and focus the research area.
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Formulate a Hypothesis
• Predict a possible answer to the
problem or question.
• Example: If soil temperatures rise,
then plant growth will increase.
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Experiment
• Develop and follow a procedure.
• Include a detailed materials list.
• The outcome must be measurable
(quantifiable).
09/03/2023 58
Designing the Experiment
• This stage of the scientific method involves designing
the steps that will test and evaluate the
hypothesis, manipulating one or more variables to
generate analyzable data. The experiment should be
designed with later statistical tests in mind, by
making sure that the experiment has controls and a
large enough sample group to provide statistically
valid results.
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Observations
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Collect and Analyze Results
• Modify the procedure if needed.
• Confirm the results by retesting.
• Include tables, graphs, and
photographs.
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Analysis
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Conclusion
• Include a statement that accepts or
rejects the hypothesis.
• Make recommendations for further
study and possible improvements to
the procedure.
09/03/2023 63
Communicate the Results
• Be prepared to present the project to an
audience.
• Expect questions from the audience.
• The results are usually published and
shared with the scientific community,
allowing verification of the findings and
allowing others to continue research into
other areas.
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Cycles
09/03/2023 65
Examples
• https://
graziano-raulin.com/supplements/phasesexa
mples.htm
09/03/2023 66
How to Write A Winning
Scientific Research Proposal?
67
Why its Worthy to Learn Grant Proposal Writing
Capacity Building
68
Contents
• General Considerations
• Research Paradigm
• Types of Research
• Requirements of a Research Project
• Genesis of a Research Project
• Development of the Research Idea
• Concept Paper
• Expected Outcomes
• Developing Research Team
• Informed Consent
• Seeking For the Funding Agency
• Research and Development in South Asia
• Reviewer’s Criteria
• Components of a Research Proposal
69
Grant proposal/Research Proposals-
Key for a Scientist’s Survival
• Grant proposal is a request for funding of the
concrete idea-based on preliminary results-for
future endeavors.
• While research paper is retrospective in nature,
research proposals in futuristic.
• Almost all universities based research are
funded by a third party-proposals are of
enormous importance
70
HF Ebel et al. The Art of Scientific Writing, second revised edition,1987- Wiley VCH
Grant proposal/Research Proposals-
Key for a Scientist’s Survival
• Proposal should share the goal effectively
• It should be convincing a potential donor
agency
• Value of proposed research
• Completion of project as describe is feasible
within fiscal time
• Expertise are available
• Inventory of publication/references
71
HF Ebel et al. The Art of Scientific Writing, second revised edition,1987- Wiley VCH
Grant proposal/Research Proposals-
Key for a Scientist’s Survival
• Existing facilities and expertise
• Detailed budget ( personnel, apparatus,
supplies, chemicals and etc.)
• Some times grant agencies give a grant form-
uniformity
72
HF Ebel et al. The Art of Scientific Writing, second revised edition,1987- Wiley VCH
Research Always Begins with a Problem
Expectations Reality
Gap = Problem
73
Research Paradigm
Dream
Discovery Design
Delivery
Infrastructure
Lab space, Basic equipment, Technical support,
Secretarial support
Research Requirements
Skilled manpower (postdoctoral or research students)
Specialised equipment, Consumables, Travel funds
76
Genesis of a Research Project
Idea development
Well informed literature survey of the field of interest
Cutting edge Research
Familiarity with the topic
Initial research ideas are often very general but good research
questions need to be quite specific.
Brainstorm
Familiarity with the topic
Reviewing the literature
Share/Discuss
Understand expectations
Keep it interesting
Formulate an Research idea/question
78
Preparation of a Concept Paper
Turning Ideas Into Research Problem
Research projects need a concept paper
helps a researcher spot holes in the research project
80
Broad Term Methodology
81
Expected Outcomes
Scientific Outcomes
New methodology
Patents
Publications
Discoveries
Socio-Economic outcomes/impact
Betterment towards the disease treatment
Development of the Economy
82
Developing Research Team-
Selection of the Suitable Experts of the
Field
Human Resources:
83
Where to Conduct the Research Project?
•Institutional Impact
•Identification of the place to conduct the desire
research.
•Infrastructure
84
Informed Consent and Consent Meeting
Research participants should be given sufficient
information about the project
Deadlines
Format of the application 86
Process of Evaluation
Remember Efforts for Research
Funding is Not for Money, It is
for a Cause
87
Why Look For Funding???
88
Types of Funded Research
Find a Sponsor
89
Top Secrets for Getting Research
Funds are Going to Reveal Now…
90
Secret-1: Numbers Game
91
Secret-2: Networking
92
Secret-3: What they Want?
93
Secret-4: Uniqueness
• Thoughtfully Planned
• Concisely Packaged
• Absolutely True
• Budget Consistent with the Proposal’s
Narrative
95
Avoid in Proposal?
• Tall Claims
• Excessive Language
• Jargon
96
Neutral Third Party Review
97
A Low Probability Game?
98
Applications Submitted to NIH
• Approximately 46,000
grant applications are
submitted to NIH each
year, of which 25-30%
are funded
• Competing grant
applications are
received for three
review cycles per year
99
How do you maximize the
chances of turning your
great idea into a winning
grant application?
100
Research Proposal-The Basic Elements
101
SMART
• Base on SMART concept
• S Specific
• M Measureable
• A Achievable
• R Realistic
• T Time Specific
102
Two Rational Question
• Why
• How
103
Research Proposals
• Why you select certain topic???
• Significance
• Implication
• Limitations
• Further Directions
104
Capture the Reviewer's Attention
• Writing for committee competition is an art –
different from research work itself.
• Clear answer of the following Qs.
– What we are going to learn as the result of
proposed project that we don’t know NOW?
– Why is it worth Knowing?
– How will we know that the conclusion is
valid?
105
Capture the Reviewer's Attention
106
Aim for Clarity
• Multidisciplinary committee member
• Avoid jargons
107
Establishment of the Context
108
Practical Considerations
109
Competitive Edge
110
Remember Win -Win
• When you approach prospective collaborators
• their enthusiasm will be proportional to their
anticipated gain (mentorship, authorship, equipment,
resources)
The donor
Your interest
interest
• Overall goals
• Specific aims
• Preliminary results
112
Research Plan
• Start with an outline
• Include sufficient information required for
evaluation
• Grant application should stand alone
• Specific and informative
• Tell the reviewer that what you are going to do and
how you will do it.
113
Research Plan
• What do you intend to do??
114
Key Components
• Title Page
• Abstract: best written after the following is written.
• The Body
– Introduction: An Introduction giving a brief statement of why the area of study
is important.
– Methods
• Sample
• Measures
• Design
• Procedures
– Results
– Conclusions
• References: A bibliography of the references cited in the proposal
• Tables
• Figures
• Appendices
• https://
www.monash.edu/rlo/graduate-research-writing/write-the-thesis/writing-a-research-
proposal
115
Other Very Important Components
A budget itemized to explain the need for the funding that you are
requesting.
116
Gantt Chart
Year One Year Two
Jan Mar- May July Sep- Nov Jan Mar- May- July Sep- Nov-
- Apr -Jun -Aug Oct -Dec - Apr Jun -Aug Oct Dec
Fab Fab
Hiring of staff
Order equipments and
chemicals
Designing andd optimization of
scheme
Syntheses/ Purification/
characterization
Toxicity studies
Biological activities of
compounds
Bioavailability studies
Research article write up
Progress report
117
Title Page
• brief yet explicit title
• the names of the principle investigator(s), the
institutional affiliation of the applicants
• name and address of the granting agency,
project dates,
• amount of funding requested, and signatures of
university personnel authorizing the proposal.
118
Abstract
• first or may be last impression of your project.
• The abstract should explain the key elements of your
research project in the future tense.
• Most abstracts state:
• the general purpose
• specific goals
• research design
• Methods
• significance (contribution and rationale)
119
Table of Contents
• The table of contents lists the sections and
subsections of the proposal and their page
numbers.
120
Introduction
• key elements of your proposal,
• statement of the problem,
• the purpose of research,
• research goals or objectives,
• significance of the research.
• background and rationale for the project and
establish the need and relevance of the
research.
121
Introduction
• How is your project different from previous
research on the same topic?
• identify the anticipated outcomes of the
research and should match up to the needs
identified in the statement of problem.
• List only the principle goal(s) or objective(s)
of your research and save sub-objectives for
the project narrative.
122
Literature Review/ Background
Reviewers want to know whether you've done
the necessary preliminary research to
undertake your project.
Literature reviews should be selective and
critical, not exhaustive.
Reviewers want to see your evaluation of
pertinent works.
123
Benefits and Feasibility of the
Proposed Project
Most proposals discuss the advantages or
benefits of doing the proposed project.
This acts as an argument in favor of approving
the project.
Also, some proposals discuss the likelihood of
the project's success.
124
Method, Procedure, Theory
• How you will run a project, if approved to do it.
126
Qualifications
• summary of the proposing individual's or
organization's qualifications to do the
proposed work-mini-resume
• The proposal audience uses it to decide
whether you are suited for the project.
• Also includes, work experience, similar
projects, references, training, and education
127
Budget/Costs and Resources Required
• detailed costs of the project
• costs of equipment and supplies, and etc.
128
Conclusions
• Bring readers back to a focus on the positive
aspects of the project.
• Urging committee to get in touch to work out
the details of the project
• Remind them of the benefits of doing the
project,
• Ensuring that you and your organization are
the right choice for the project.
129
Appendices
130
Issues
• Ethical issues
– Privacy
– Intellectual Property
– Confidentiality
• Other issues
– Continuous participation
131
Review of Research Grants
REVIEW CRITERIA:
– Significance
– Approach
– Innovation
– Investigator-fame of PI and Co-PI
– Environment-organization
– Overall Evaluation & Score Reflects Impact on
Field
132
Review Criteria (Continued)
• Significance: Does the study address an important problem?
How will scientific knowledge be advanced?
135