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Sex Determination &

Sex Linkage
Sex Determination • The ‘Transformer’ Gene of Drosophila, a
recessive on chromosome 3 of Drosophila
Mechanism when homozygous transform a diploid
female in to a sterile male.
• “Mating Type” in Microorganism, in
1. Sex Chromosome microorganism is under control of single
gene. Haploid individuals have the same
Mechanism
a. Heterogametic Males, in humans and alleles of the “mating-type” locus usually
all mammals the presence of Y cannot fuse with each other to form a zygote
chromosomes shows maleness. While but haploid cells of opposite alletic at this
females that have the same pair of locus may fuse.
gamete (XX), the males produce two
gametes (XY).
b. Heterogametic Females, The
heterogametic females have ZW
Sex-Linked Inheritance
instead of XX and for the males is ZZ.
E.g, chicken Sex linkage describes the sex-specific patterns of
inheritance and presentation when a gene
mutation (allele) is present on a sex chromosome
2. Genic Balance (allosome) rather than a non-sex chromosome
(autosome)
Y chromosome in male present fertility but
not determine their sex. Instead, the factors
for maleness residing in all the autosomes are Sex Influenced Traits
weighed against the factors for femaleness The genes governing ex-influenced traits may
reside on any of the autosomes or on the
residing on X chromosome
homologous portions of the sex chromosomes..
E.g, Man & Woman baldness
3. Haplodiploidy
Sex chromosome are not involved in this
Sex Limited Traits
Some autosomal genes may only come to
mechanismof sex determination, it can be the expression in one of the sexes either because of
quality-quantity of food and other factors. e.g differences in the internal hormonal environment
bees or because of anatomical dissimilarities. When
the penetrance of a gene in one sex is zero, the
trait will be sex-limited
4. Single-Gene Factor
• Complementary Sex Factor, known to Sex Reversal
produce male by homozygosity at Female chickens (ZW) that have laid eggs have
single-gene locus as well as by haploidy been known to undergo not only a reversal of the
secondary sexual characteristics such as
development of cock-feathering, spurs, and
Tisha Tabhita Siregar --BESP18 crowing, but also the development of testes

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