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Chapter 16

Nutrition in Metabolic &


Respiratory Stress

© 2007 Thomson - Wadsworth


Body’s Response to
Stress & Injury
• Stress response • Nutrients are
 Infection mobilized from
 Burns storage
 Fractures • Heart rate and
 Surgery respiration
 Extensive bleeding increase
• Body focuses on • Blood pressure
immediate survival rises

© 2007 Thomson - Wadsworth


Hormonal Response to Stress

• Epinephrine & • Cortisol


norepinephrine  Enhances protein
 Stimulate heart degradation
muscle • Aldosterone &
 Alter blood flow rate antidiuretic hormone
 Raise basal  Help maintain blood
metabolism volume
• Glucagon  Stimulate kidneys to
 Releases nutrients reabsorb sodium &
from storage water

© 2007 Thomson - Wadsworth


The Inflammatory Response
• Serves to • Classic signs
 Contain & destroy  Swelling
infectious agents  Redness
 Prevent further  Heat
tissue damage  Pain
• Dilation of arterioles
• Constriction of
venules

© 2007 Thomson - Wadsworth


© 2007 Thomson - Wadsworth
Nutrition Treatment

• Problems • Diet goals


 Hypermetabolism &  Preserve lean tissues
negative nitrogen  Maintain immune
balance defenses
• Wasting  Promote healing
 Hyperglycemia &
insulin resistance
• Need to balance
• Increases infection risk overfeeding &
underfeeding

© 2007 Thomson - Wadsworth


Estimating Requirements
• Energy • Lipids: 40% of
 Harris-Benedict kcalories
equation (BEE)
• Vitamins &
• Protein
minerals
 1.0-2.0 g/kg
 May have
• Carbohydrates: increased needs
70% of kcalories

© 2007 Thomson - Wadsworth


© 2007 Thomson - Wadsworth
Approaches to Nutrition Care

• Initial care: maintain fluid &


electrolyte balance
• May need enteral and/or
parenteral support
• High-kcalorie, high-protein diet
Take care not to overfeed
Reassess frequently

© 2007 Thomson - Wadsworth


Nutrition & Respiratory Stress
• Respiratory stress
Reduced oxygen
Increased carbon
dioxide
• Labored breathing
Interferes with food
intake
Weight loss &
malnutrition

© 2007 Thomson - Wadsworth


© 2007 Thomson - Wadsworth
Chronic Obstructive
Pulmonary Disease (COPD)

© 2007 Thomson - Wadsworth


Chronic Obstructive
Pulmonary Disease (COPD)
• Persistent obstruction • Causes
of airflow  Smoking
 Chronic bronchitis  Chronic respiratory
• Excessive mucus infections
secretions  Occupational exposure to
• Productive cough dusts or chemicals
 Emphysema  Genetic susceptibility
• Breakdown of lung’s
elastic structure
• Goals
• Dyspnea  Improve food intake
 Maintain healthy weight
 Prevent muscle loss
 Improve exercise
endurance
© 2007 Thomson - Wadsworth
Treatment
• Small, frequent
meals
• Adequate fluids
• Liquid supplements
• Exercise plan

© 2007 Thomson - Wadsworth


Respiratory Failure

• Gas exchange • Causes


between air & blood  Obstruction
is greatly impaired  Weakness or
• Consequences paralysis of muscles
 Hypoxemia  Embolus
 Hypercapnia  Toxic substances
 Hypoxia  Severe trauma &
infection
 Acidosis
 Cyanosis

© 2007 Thomson - Wadsworth


Treatment

• Support lung function


• Correct underlying disorder
• Careful monitoring of fluid
• Medications

© 2007 Thomson - Wadsworth


Treatment

• Chronic lung disease


Oxygen therapy
• Acute respiratory
distress syndrome
(ARDS)
Mechanical ventilation

© 2007 Thomson - Wadsworth


Nutrition Care

• Individualize according to
patient’s condition
• Enough energy & protein to
support lung function
without overtaxing the
respiratory system

© 2007 Thomson - Wadsworth


Nutrition in Practice

Multiple Organ Failure

© 2007 Thomson - Wadsworth


Multiple Organ Failure
• Cause of death in ½ • Organs
of ICU patients  Lungs
 Liver
• A failure of two or  Kidneys
more organ systems  GI tract
• Chemical mediators • Causes
can cause systematic  Acute respiratory
response syndrome failure
(SIRS), leading to  Trauma
 Sepsis
shock & organ failure
 Burns
 Extensive surgery
 Pancreatitis

© 2007 Thomson - Wadsworth


© 2007 Thomson - Wadsworth
© 2007 Thomson - Wadsworth
Risk Factors

• Age over 55 • Severity of tissue


• Prior chronic injury
illness • Length of time
• Persistent SIRS between injury &
• Major infection arrival at hospital
• Blood • Malnutrition
transfusions

© 2007 Thomson - Wadsworth


Treatment

• Mechanical • Hemofiltration or
ventilation dialysis
• Fluid & • Antibiotic therapy
electrolytes for infection
• Medications to • Enteral &
sustain or parenteral
increase cardiac nutrition
output & blood
pressure

© 2007 Thomson - Wadsworth

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