VTE Algorithm in COVID-19

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Symptomatic COVID-19 patient requiring admission

Mechanical
Critically-ill Yes Prophylactic anticoagulation thrombo-prophylaxis
(Needing ICU (Prefer intermediate-dose) (if absolute
admission)? contraindications for
anticoagulation)
Clinical deterioration &/or
Rapid ↑ in D-dimer levels > 6x
No Or Dynamic clinical
Confirmed VTE on imaging assessment

Yes No
Daily
Admission in Therapeutic Continue prophylaxis D-dimer levels,
general ward? anticoagulation till rest of hospital stay platelet count,
(For total 3 AND creatinine
months) for 2 to 6 weeks after clearance
Yes
discharge

Yes
Prophylactic anticoagulation
No Consider prophylaxis after
Standard-dose Becomes
discharge for 2 weeks in
vs critically-ill?
patients at high risk for VTE
Intermediate-dose

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