ALZHEIME

R
Claudia Iglesias
Pablo Ibáñez
 TABLE OF
0 CONTENTS ADVANCES
02 03
AND
1
WHAT IS IT? SYMPTOMS MEDICINES

04
BRAIN 05
EVOLUTION VOCABULARY
 WHAT IS IT?
0 Neurodegenerative disease that causes
problems with memory, thinking and
behaviour.

1
 SYMPTOMS

02 Difficulty in distinguishing
people and things.

Disorientation in 01
time and place.

03 Changes in memory, mood

and personality.
NEURONA
L DEATH 02
 Accumulation of beta-amyloid protein
plaques.
 And accumulation of neurofibrillary
tangles of Tau protein.
03.
ADVAN
CES
 BIOMARKE
RS
which allow the levels of beta-amyloid
and tau proteins in the cerebrospinal fluid
to be analysed from the fluid extracted by
lumbar puncture.
 IMMUNO-
INFRARED
SENSOR
● Researchers at the University of Bochum
in Germany have developed an immuno-
infrared sensor that can detect signs of the
disease in the blood up to 17 years before
the first clinical symptoms appear.
 03. MEDICINES

Aducanuma Saracatinib
b

Vaccine Tau Lecanemab

 Aducanumab

Aducanumab reduces the

amyloid plaques, giving the
patient a more bearable life,
although it does not cure it
completely.
 Saracatinib

The primary function of these

monoclonal antibodies is to mimic
natural antibodies that are produced
as a response of the immune system
to external mechanisms.
Vaccine Tau

It aims to produce
antibodies to prevent
aggregation of the tau
protein and facilitate its
removal.
This study was conducted
with 30 participants
between 2013 and 2015.
 Lecanemab

This medicine slows neuronal

deterioration by 27%.
This study was carried out on 1800
patients with mild dementia.
The results of the medicine will be
presented in November at the
Alzheimer's Clinical Trials
Conference in San Francisco.
 04
T
he brain evolut
ion
01 02 03 04 05
Vocabu
lary
• Disease
• Neurodegenerative
• Degeneration
• Death of neurons

05
• To refer to
• To be involved
• Cognitive impairment
 Vocabulary

05
• Genetic
• Environement
• To be atrophied
• Clusters
• Treatment
• Inhibiter
 RESOURCES
Webside
● https://saludos.cualtis.com/en-investigacion-una-vacuna-contra-el-alzheimer/Scientist making
● https://canohealth.com/es/noticias/blog-es/avances-en-la-cura-del-alzheimer/
● https://www.nia.nih.gov/espanol/medicamentos-enfermedad-alzh
eimer
● https://www.mayoclinic.org/es-es/diseases-conditions/alzheimers-
disease/in-depth/alzheimers/art-20048103

Other resources
● https://youtu.be/I6K10aif0tE
Thanks!!!
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