Carcinoma Penis

Lavanya (1901001076)
Table of contents

01 02
Aetiology Clinical features
Causes and risk factors Signs and symptoms
Aetiology
 Circumcision soon after birth confers immunity
against carcinoma but later circumcision does not
seem to have the same benefit, with the assumption
that smegma is in some way carcinogenic
 Smoking
 Chronic balanoposthitis
 Phimosis
 Sexually transmitted diseases
Aetiology
 Erythroplasia of Queret is persistent rawness of glans
penis
 Condyloma acuminata (by HPV), Balanitis xerotica
obliterans
 Leukoplakia of glans
 Long standing genital warts
 Paget’s disease of penis
 HIV infection
Clinical features
 Many patients present late as a fungating/
ulcerative growth.
 The growth is often large and secondary
infection causes a foul, bloody discharge
 There is typically little or no pain.
 Around 50% have inguinal lymph node
enlargement at presentation but the nodal
enlargement often reflects infection.
 Palpable hard, nodular inguinal lymph nodes on
both sides may be present. External iliac lymph
nodes may be palpable.
Clinical features
 In many, the prepuce is non-retractile and must
be split to view the lesion.
 If untreated, the whole glans may be replaced
by a fungating offensive mass.
 Later, the inguinal nodes can erode the skin of
groin and in rare cases, death of the patient can
result from erosion of the femoral or external
iliac vessels.
 Pain, oedema, tenderness, redness develops
once infection.
Carcinoma penis
Thank you!