Myocardial Infarction

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MYOCARDIAL

INFARCTION

UMAPRAKASH
MSC(N)1ST Years
DEFINITION
MI is defined as a diseased condition which is
caused by reduced blood flow in a coronary artery
due to atherosclerosis & occlusion of an artery by an
embolus or thrombus. MI or heart attack is the
irreversible damage of myocardial tissue caused by
prolonged ischemia & hypoxia
TYPES OF INFARCTS
According to anatomic region of left ventricle
involved:
 Anterior
 Posterior
 Lateral
 Septal
 Circumferential
 Combinations- Anterolateral, Posterolateral,
Anteroseptal
ETIOLOGY
 Age
 Tobacco smoking
 Gender
 Hypertension
 Diabetes
 Drug abuse
 Hyperlipoproteinaemia
 Obesity
 Family history of Ischaemic
 Stress
Heart Disease
 Alcohol
 Hyperhomocysteinemia
 Chronic kidney disease
DIAGNOSTIC EVALUATION
Serum cardiac markers :
 Creatinine phosphokinase (CK)

 Lactic dehydrogenase (LDH)

 Cardiac specific troponins (cTn)

ECG changes :
 ST segment elevation

 T wave inversion
DIAGNOSTIC EVALUATION

 MAGNETIC RESONANCE IMAGING (MRI)

 CHEST X- RAY

 ANGIOGRAPHY

 POSITRON EMISSION TOMOGRAPHY (PET scan)

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