Scribd Logo
Upload

Welcome to Scribd!

  • Metabolism Enzymes

    Uploaded by

    nprashantshekhar
    6 views8 pages
    The document summarizes the steps of enzyme-catalyzed reactions: 1) Substrates enter and bind to the active site of the enzyme. 2) The active site holds the substrates through weak interactions and lowers their activation energy to speed up the reaction. 3) The substrates are converted to products within the active site. 4) The products are then released from the active site, leaving the enzyme available to catalyze another reaction.

    Original Description:

    IITK_ Lif

    Copyright

    © © All Rights Reserved

    Available Formats

    PPT, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The document summarizes the steps of enzyme-catalyzed reactions: 1) Substrates enter and bind to the active site of the enzyme. 2) The active site holds the substrates through weak interactions and lowers their activation energy to speed up the reaction. 3) The substrates are converted to products within the active site. 4) The products are then released from the active site, leaving the enzyme available to catalyze another reaction.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    6 views8 pages

    Metabolism Enzymes

    Uploaded by

    nprashantshekhar
    The document summarizes the steps of enzyme-catalyzed reactions: 1) Substrates enter and bind to the active site of the enzyme. 2) The active site holds the substrates through weak interactions and lowers their activation energy to speed up the reaction. 3) The substrates are converted to products within the active site. 4) The products are then released from the active site, leaving the enzyme available to catalyze another reaction.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    of 8

    Figure 8.

    14

    Substrate

    Active site

    Enzyme Enzyme-substrate
    complex
    (a) (b)
    1 Substrates enter active site.
    2 Substrates are held
    in active site by weak
    interactions.

    Substrates
    Enzyme-substrate
    complex 3 Active site can
    lower EA and speed
    up a reaction.
    6 Active
    site is
    available
    for two new
    substrate
    molecules.
    Enzyme

    5 Products are 4 Substrates are


    released. converted to
    products.
    Products
    Enzymatic “Activators”
    Cofactors Coenzymes
    • Non-protein, small • Non-protein, organic
    inorganic compounds & molecules
    ions – Bind near active site
    – Bound within protein’s – Vitamins
    tertiary structure • NAD+
    • Mg, K, Ca, Zn, Fe, C • FAD+
    • Coenzyme A
    Optimal temperature for Optimal temperature for
    typical human enzyme (37°C) enzyme of thermophilic
    (heat-tolerant)
    Rate of reaction

    bacteria (77°C)

    0 2060 40
    80 100 120
    Temperature (°C)
    (a) Optimal temperature for two enzymes
    Figure 8.16b

    Optimal pH for pepsin Optimal pH for trypsin


    (stomach (intestinal
    enzyme) enzyme)
    Rate of reaction

    0 1 5 2 3 4 6 7 8 9 10
    pH
    (b) Optimal pH for two enzymes

    You might also like