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    The document discusses point of care testing for diabetes. It compares diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic syndrome (HHS), noting that DKA has a short term onset and frequently has an osmolarity over 320mOsm/kg, significant hyperketones/acidosis, and modest hyperglycaemia primarily in type 1 diabetes patients, with a 5% mortality rate. HHS has a long term onset and frequently has an osmolarity under 320mOsm/kg, no or low ketones/acidosis, severe hyperglycaemia primarily in type 2 diabetes patients, with a higher 30% mortality rate. It also discusses calculating and

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    The document discusses point of care testing for diabetes. It compares diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic syndrome (HHS), noting that DKA has a short term onset and frequently has an osmolarity over 320mOsm/kg, significant hyperketones/acidosis, and modest hyperglycaemia primarily in type 1 diabetes patients, with a 5% mortality rate. HHS has a long term onset and frequently has an osmolarity under 320mOsm/kg, no or low ketones/acidosis, severe hyperglycaemia primarily in type 2 diabetes patients, with a higher 30% mortality rate. It also discusses calculating and

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    Download as PPTX, PDF, TXT or read online from Scribd
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    1 views9 pages

    PoCT Lab Intro

    Uploaded by

    tyhbbhh
    The document discusses point of care testing for diabetes. It compares diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic syndrome (HHS), noting that DKA has a short term onset and frequently has an osmolarity over 320mOsm/kg, significant hyperketones/acidosis, and modest hyperglycaemia primarily in type 1 diabetes patients, with a 5% mortality rate. HHS has a long term onset and frequently has an osmolarity under 320mOsm/kg, no or low ketones/acidosis, severe hyperglycaemia primarily in type 2 diabetes patients, with a higher 30% mortality rate. It also discusses calculating and

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    Download as pptx, pdf, or txt
    of 9

    Point of Care Testing

    Core Biomedical Science 2


    PoCT
    1. Carry out analysis of urine samples A and B
    (Diabetes Mellitus)
    2. Determine osmolar gap
    3. Investigate Diabetes Insipidus
    4. Online Assignment 4
    PoCT
    PoCT
    COMPARISON OF DKA AND HHS
    Sign Diabetic Hyperosmolar
    Ketoacidosis hyperglycaemic
    syndrome
    Timescale short term long term onset
    Osmolarity rarely > 320mOsm/kg frequently <
    320mOsm/kg

    Ketones/acidosis Significant hyper - None or low


    Hyperglycaemia Modest Severe
    T1D v T2D T1D T2D
    Mortality 5% 30%
    PoCT
    PoCT
    2. Osmolar Gap
    - difference between calculated and measured
    • calculated = determine from sodium, glucose
    and urea concentrations
    • measured by osmolarity
    • should be equal !
    • what can cause osmolar gap ?
    PoCT
    PoCT
    Self Study and Assignment 4
    PoCT
    Self Study and Assignment 4

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