objectives

 Structure

 Synthesis

 Types

 Uses

 effects
structure
• Cyclopentanoperhydro phenanthrene
ring

• 27 carbon atoms

• Double bond between carbon 5 and 6

• 8 carbon side chain

• Hydroxy group at carbon 3

 synthesis
• Condensation
• HMG –CoA synthesis
• Rate limithing step
• Production of 5-carbon unit
• Condensation of 5 – carbon unit
• Cutting of size
 types
• HDL - high density lipoprotein
good cholesterol
transports cholesterol from
peripheral tissue to liver
• LDL - low density lipoprotein
bad cholesterol
transports cholesterol from liver
to peripheral tissue
uses