Duchenne Muscular

Dystrophy (DND)
By: Jasdeep Singh
 How does Duchenne Muscular Dystrophy (DMD)
happen?

Duchenne Muscular Dystrophy is a genetic

disorder characterized by the absence or deficiency
of a protein called dystrophin. Dystrophin is crucial
for maintaining the integrity and strength of muscle
fibers. Without sufficient dystrophin, muscle cells
become damaged and progressively weaken over
time.
Is It Recessive or Dominant? How common is
it?

Since Duchenne Muscular Dystrophy is an X-linked

recessive disorder, it is relatively rare, occurring in
approximately 1 in every 3,500 to 5,000 male births.
It primarily affects males because the DMD gene is
located on the X chromosome.
Symptoms

● muscle weakness
● difficulty walking
● frequent falls
● enlarged calves
● respiratory complications
 Treatments
As of now, there is no cure for Duchenne Muscular
Dystrophy. However, there are several ways to manage
symptoms and improve the quality of life for affected
individuals. These include physical therapy and
medications to address specific symptoms. Steroids are
also commonly prescribed to help slow the progression
of muscle weakness.