ACUTE

PANCREATITIS
DR.HAWA TELA MAGANGA
MMAN YR 2
MAKERERE UNIVERSITY
12/02/2023 DATE:6/4/2023 0900HRS
 DISCLOSURES

•I have no financial disclosures or

conflicts of interest with the presented
material in this presentation.

12/02/2023
 OBJECTIVES
1) Describe the clinical features and severity of the acute
pancreatitis, including the presence of complications .
2) Relevant diagnostic tests and their implications for the
diagnosis and management of the condition.

3) Outlining the current critical care management and

interventions to prevent or manage complications.

4) Identifying any possible challenges or obstacles to the

patient's care.
12/02/2023
1.DEFINITION OUTLINE
2.CASE PRESENTATION
3.EPIDEMIOLOGY
4.PATHOPHYSIOLOGY
5.CLINICAL PRESENTATION
6.DIAGNOSIS
7.CASE MANAGEMENT
8.OUTCOME
9.SUMMARY
10.FURTHER READING
12/02/2023
DEFINITION
• Acute pancreatitis (AP) is an acute inflammatory
disorder of the pancreas.
• Leading cause of hospital admission for
gastrointestinal (GI) disorders & the incidence is rising.
• Majority have a self-limiting disease, those with
severe AP account for 2.4% of ICU beds occupied in
England and Wales, and with a in-hospital mortality of
about 40%.

12/02/2023
 CAUSES OF ACUTE PANCREATITIS
MECHANISM
•OBSTRUCTIVE- gall stones or biliary sludge
-After ERCP
-Cystic fibrosis

•TOXIC -Chronic alcohol use

-hypertriglyceridemia
-drugs ( immunosuppressants, steroids, azathioprine )
-diuretics(furosemide ,thiazide )
- antibiotics(metronidazole)sulphonamides
•ISCHAEMIA/REPERFUSION shock states,cardiopulmonary bypass surgery
•INFECTIONS- viruses :cytomegalovirus,mumps,cocksackie B and Epstein barr
virus.pararasites,ascaris
•TRAUMA-blunt or penetrating trauma
•OTHERS- idiopathic,autoimmune(schlerosing cholangitis)
12/02/2023
12/02/2023
12/02/2023
12/02/2023
12/02/2023
 CASE REPORT

12/02/2023
 CLINICAL PRESENTATION

12/02/2023
EPIDEMIOLO
GY

12/02/2023
 EPIDEMIOLOGY

12/02/2023
 PATHOPHYSIOLOGY

12/02/2023
 PATHOPHYSIOLOGY

12/02/2023
DIAGNOSIS

12/02/2023
 DIFFERENTIAL DIAGNOSIS

12/02/2023
 MANAGEMENT

12/02/2023
 TREATMENT

12/02/2023
 CASE MANAGEMENT/DECISION
MAKING

12/02/2023
 OUTCOMES

12/02/2023
 PREVENTION

12/02/2023
 FURTHER READING
•

12/02/2023