Development of the Urinary

System
 Learning outlines
• Nephrogenic cord

• Collecting system

• Migration of kidneys and variations in arterial

system

• Anomalies
 Development of Kidneys

• UROGENITAL RIDGE

• From IEIM
• On each side of aorta
• Nephrogenic cord

• Gonadal cord
 Nephrogenic cord

1. Pronephrons
– Bilateral
– Appear early in the 4th wk
– Opens into cloaca
– Soon degenerate
– Pronephric ducts persist
 Nephrogenic cord

2. Mesonephros
– Appear late in the 4th wk
– Interim kidneys
– Consists of glomeruli &
tubules
– Mesonephric ducts
– Opens into cloaca
– Degenerates end of 1st
trimester
Mesonephros
 Metanephros

• Primordia of
permanent kidneys
– Develop at 5th wk
– Functional at 9th wk
– Urine formation
continues
Permanent kidneys

• The ureteric bud

• The metanephrogenic
blastema
Development: Kidneys
 Development of the Collecting System

• Ureteric bud becomes

the ureter
• Its cranial bud
branches
– 1st generations
– 2nd generations
 Metanephric system
– Collecting system
• derived from the ureteric bud.
– It dilates to create the ureter, renal pelvis, major
and minor calyces and collecting tubules –
terminating at the distal convoluted tubule.
– Excretory system – derived from the metanephric
blastema.
• Form the nephron.
• Form the Bowman’s capsule
• Proximal convoluted tubule, loop of Henle and
distal convoluted tubule
Bladder & Urethra
Development of the Urinary Bladder
Development of the Urinary Bladder
Development of the Urinary Bladder
Development of Urethra
Positional Changes of the Kidneys

Changes in Blood Supply of the Kidneys

Changes in Blood Supply of the Kidneys
Major Anomalies
 QUIZ (6%)

Please match each urinary term with its characteristic?