STRUCTURE ELUCIDATION

OF PARACETAMOL
Presented by: Tehreem Farooq (6601)
Hifza Saif (6615)
Sadia Hakim (6621)
Noor Fatima (6627)
Sobia Zahra (6633)

Presented to : Dr. Malik Saad Ullah

5th Semester

Faculty of Pharmaceutical sciences, GCUF

 UV-VISIBLE SPECTRUM OF
PARACETAMOL

The Principle of UV-Visible Spectroscopy is based on the absorption of

ultraviolet light or visible light by chemical compounds, which results in the
production of distinct spectra. Spectroscopy is based on the interaction
between light and matter.
 In the UV–vis spectrum,
Paracetamol exhibits maximum
absorbance (λmax) at 243 nm.
IR SPECTRUM OF PARACETAMOL

N-H

O-H
H1 NMR SPECTRUM OF
PARACETAMOL
MASS SPECTRUM OF PARACETAMOL

Fragmentation of paracetamol
MASS SPECTRUM OF PARACETAMOL
 RESULT AND CONCLUSION

• The UV-visible spectra of solutions containing 100 mg/l paracetamol was carried out and the
maximum absorbance was found at 243nm for all solutions.
• IR spectra: C=C, C=O, aromatic ring, sp2 C-H, sp3 C-H, OH, N-H functional groups are present.
• NMR spectra: It shows the presence of para coupled aromatic protons at the position 1 and 4 in
the aromatic ring
• Mass spectra: Mass of the compound is 151.
 CHEMICAL STRUCTURE OF
ACETAMINOPHEN

Molecular formula:
C8H9NO2
 ANY
QUESTIONS?