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Medical, Lactation, Mastitis
Medical, Lactation, Mastitis
LACTATION
AND
BREASTFEEDIN
G
Lactation….
1. Lactation refers to the physiological process by
which a woman's body produces and secretes milk
from the mammary glands in the breasts, typically
following childbirth.
2. It is a normal and natural part of the reproductive
process in mammals.
3. It is initiated by hormonal changes, primarily
involving the hormones prolactin and oxytocin.
Colostrum….
1.Colostrum is the first form of milk produced by the
mammary glands in the breasts for the first 2 days
following delivery.
2. It is a thick, yellowish fluid that is rich in nutrients
and antibodies, providing essential components for the
newborn's health and immune system.
3. It is deep yellow serous fluid and is alkaline in
reaction.
Composition of colostrum….
• Protein
• Carbohydrate
• Fat
• Vitamin A Composition of colostrum
• Sodium and chloride
• Immunoglobin A
• Complement factors
• Macrophages
• Lymphocytes
• Lactoferrin
• Lactoperoxidase
Breast milk vs colostrum
Breast milk Colostrum
8.6
7.5
4.2
3.2
2.3
1.2
P r ot ei n F at Car bo hydr at es
Physiology of lactation…
1. Preparation of breasts
(Mammogenesis)
2. Synthesis and secretion from breast alveoli
(lactogenesis)
3. Ejection of
milk
(galactokinesis)
4. Maintenance of
lactation
1. Mammogenesis: Pregnancy is associated
with remarkable growth of both ductal
and lobuloalveolar systems. An intact
nerve supply is not essential for the
growth of mammary glands during
pregnancy.
2. Lactogenesis: The alveolar cells are the
principal sites for production of milk.
Milk secretion starts on 3rd or 4th
postpartum day.
• Around this time, the breasts become
engorged, tense, tender and feel warm.
• In spite of a high prolactin level during
pregnancy, milk secretion is kept in abeyance.
• Progesterone and estrogen make breast tissue
unresponsive to prolactin.
• After delivery , when progesterone and
estrogen are withdrawn, prolactin begins its
milk secretion.
• Prolactin , insulin , growth hormone, and
glucocorticoids are important hormones in this
3. Galactokinesis: Oxytocin is the major
galactokinetic hormone.
• Discharge of milk from the mammary glands
depends not only on the suction exerted by the
baby during suckling but also on the contractile
mechanism which expresses the milk from the
alveoli into the ducts.
• Prolactin and oxytocin: Prolactin stimulates
alveolar epithelium to secrete milk and oxytocin
stimulates the myoepithelial cells that
surrounds the alveolar epithelium to contract
and to eject the milk from the acini to the duct.
• 4. Galactopoiesis: Prolactin is an
important galactopoietic hormone.
• For maintenance of effective and
continuous lactation, frequency of
suckling (>8/24 hours) is essential.
• Distension of the alveoli by retained milk
is due to failure of suckling. This causes
decrease in milk secretion by the alveolar
epithelium.
• Ductal and alveolar distension due to
failure of milk transfer (suckling) is a cause
of lactation failure.
Lactational
reflex arc and
role of prolactin
and oxytocin
MILK PRODUCTION: A healthy mother will produce about 500-
800 mL of milk a day to feed her infant. This requires about 750
Kcal/day for the mother, which must be made up from diet or from
her body store. For this purpose a store of about 5 kg of fat during
pregnancy is essential to make up any nutritional deficit during
lactation.
Demand feeding: The baby is put to the breast as soon as the baby becomes
hungry. There is no restriction of the number of feeds and duration of
suckling time.
Duration of feed: The initial feeding should last for 5-10 minutes at each
breast. This helps to condition the letdown reflex. Thereafter, the time spent
is gradually increased. Baby is fed from one breast completely so that baby
gets both the foremilk and the hind milk. Then the baby is put to the other
breast if required. Hind milk is richer in fat and supplies more calories and
satiety to the infant. The next feed should start with the other breast
Night feed: In the initial period, a night feed is required to avoid long
interval between feeds of over 5 hours. It not only eliminates excessive
filling and hardening of the breasts but also quietest and ensures sound
sleep for the baby. However, as the days progress, the baby becomes
satisfied with the rhythmic 3-4 hourly feeding.
Infants • Very low birth weight baby • Severe degree of cleft palate
• Asphyxia and Intracranial • Galactosemia
stress
• Acute illness
Acute mastiti
Definition
Mastitis is a medical term that refers to the
inflammation of the breast tissue.
Signs include:
(b)Presence of toxic features
(b) Presence of a swelling on the breast.
(c) The overlying skin is red, hot and flushed and feels tense
and tender.
Diagnosis: Microscopic examination of breast
milk, showing leukocytes more than 10/mL and
bacterial count more than 10³/ml., supports the
diagnosis of mastitis.
Complications: It may lead to the formation of a
breast abscess.
Prophylaxis: Thorough handwashing before each
feed, cleaning the nipples before and after each
feed, and keeping them dry, reduce the nosocomial
infection .
Management: (a) Breast support
(b) Plenty of oral fluids
(c) Breastfeeding is continued with good attachment. Nursing is
initiated on the uninfected side first to establish let down
(d) The infected side is emptied manually with each feed
(e) Dicloxacillin is the drug of choice. A dose of 500 mg every 6
hours orally is started till the sensitivity report available.
Erythromycin or clindamycin is an alternative to patients who are
allergic to penicillin. Antibiotic therapy is continued for 10-14
days
(f) Analgesics (ibuprofen) are given for pain
(g) Milk flow is maintained by breastfeeding the infant. This
prevents proliferation of Staphylococcus in the stagnant milk. The
BREAST ENGORGEMENT: Bilateral generalized
tenderness of breasts is seen on 2 to 4 days postpartum.
Low grade fever is often associated. It is due to interstitial
oedema or accumulation of excess of milk. It is treated with
worm compress followed by expression (by hand or pump)
of milk. Continued breast feeding is helpful .
BREAST ABSCESS: Features are
(1) Flushed breasts not responding to antibiotics promptly.
(2) Brawny oedema of skin
(3) Marked tenderness with fluctuation
(4) Swinging temperature.
Management of abscess….
1.Breast abscess is to be drained under general anesthesia
by a deep radial incision extending from near the areolar
margin to prevent injury of the lactiferous ducts.
2.Incision perpendicular to the lactiferous ducts increases
the risk of fistula formation and ductal occlusion.
3.Finger exploration is done to break up the walls of the
loculi. The cavity is loosely packed with gauze which
should be replaced after 24 hours by a smaller pack.
4.The procedure is continued till it heals up. The abscess
can also be drained by serial percutaneous needle
aspiration under ultrasound guidance.
• Breastfeeding is continued in the uninvolved
side.
• The infected breast is mechanically pumped
every 2 hours and with every let down.
• Once cellulitis has resolved, breastfeeding from
the involved side may be resumed.
• Antibiotics to be continued depending upon the
culture report of pus .
• Breast pain may be due to engorgement,
infection (C. albicans), nipple trauma, clogged
milk, mastitis or occasionally with latching on or
Treatment: For maintenance of effective lactation in an otherwise healthy
individual, the following guidelines are helpful.
• Antenatal:
(1) To counsel the mother about the advantages of breast milk
(2) To take care of any breast abnormality, especially a retracted nipple and to
maintain adequate breast hygiene, since 36 weeks of pregnancy.
• Puerperium:
(3) To encourage adequate fluid intake
(4) To nurse the baby regularly
(5) Painful local lesion is to be treated
(6) Metoclopramide, intranasal oxytocin and sulpiride (selective dopamine
antagonist) have been found to increase milk production. They act by
stimulating prolactin secretion. Metoclopramide given in a dose of 10 mg
thrice daily is found helpful.
INADEQUATE MILK PRODUCTION: The normal volume of milk
produced at the end of first postpartum week is 550 mL/day. By 2-3 weeks it
is increased from 80 about 800 mL/day. Production peaks at 1.5-2.0 L/day.
The causes of inadequate milk production are:
(1) Infrequent suckling
(2) Depression or anxiety state in the puerperium
(3) Reluctance or apprehension to nursing
(4) III- development of the nipples
(5) Painful breast lesion
(6) Endogenous suppression of prolactin (retained placental bits)
(7) Prolactin inhibition (ergot preparations diuretics, pyridoxine)
(8) Previous breast surgery
(9) Insulin resistance
(10)High androgen levels.