Nervous Nle Intensive

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Disorders of the

Nervous System

Prepared by:Jem Sombilla RN,CNN,MAN


National/International Lecturer

NEUROLOGIC DISORDERS
Anatomy and Physiology
FUNCTIONS:

1.Sensory Input(internal and external stimulus)


2.Integration(Brain and Spinal Cord)
3.Mental Activity
4.Control Muscles and Glands(SNS/PNS)
5.Homeostasis(Hypothalamus)

NEUROLOGIC DISORDERS
Anatomy and Physiology

NEUROLOGIC DISORDERS
Anatomy and Physiology
DIVISIONS OF NERVOUS SYSTEM
CNS PNS

CARDIOVASCULAR DISORDERS
CENTRAL NERVOUS SYSTEM

NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM
BRAIN FUNCTIONS:
1.Cerebrum
 Frontal Lobe(Brocas Area)

 Parietal Lobe

 Temporal Lobe(Wernicks
Area)

 Occipital Lobe

NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM

2.Cerebellum-little brain

NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM
BRAIN FUNCTIONS:
3.Brainstem
3.1Diencephalon
 Thalamus -most sensory inputs
 Hypothalamus -homones, ANS control

 Epithalamus -sleep wake cycle(concsist of pineal gland)

3.2 Midbrain -movement of body and head/visual-auditory


reflexes
3.3 Pons
3.4 Medulla
Oblongata NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM
RIGHT BRAIN LEFT BRAIN

NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM
SPINAL CORD
 Composed Ascending and Descending pathways
 Center for reflex acts
Origin of ANS:
 Craniosacral segment(origin of PNS)
 Thoracolumbar segment(origin of SNS)
 Damage of spinal cord will lead to paralysis

NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM
PROTECTIVE STRUCTURES OF CNS
1.Cranium
-composed of 8 bones
-with junctions called sutures
2.Vertebral column
(7-C,12-T,L-5-S,5,C-4)
3.Meninges
 Pia Mater
 Arachnoid
 Dura Mater
4.CSF-cushions/protect the brain
-Regulate ICP
5.BBB(Blood Brain Barrier)
NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM

NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM

NEUROLOGIC DISORDERS
CENTRAL NERVOUS SYSTEM

NEUROLOGIC DISORDERS
PERIPHERAL NERVOUS SYSTEM

NEUROLOGIC DISORDERS
PERIPHERAL NERVOUS SYSTEM

1.CRANIAL NERVES 12-PAIRS


2.SPINAL NERVES: 31-PAIRS
8 cervical
12 thoracic
5 lumbar
5 sacral
1_coccygeal
31

3.AUTONOMIC NERVOUS SNS


SYSTEM PNS

NEUROLOGIC DISORDERS
CRANIAL NERVES

NEUROLOGIC DISORDERS
CRANIAL NERVES

NEUROLOGIC DISORDERS
AUTONOMIC NERVOUS SYSTEM
ORGAN SYSTEM SYMPATHETIC PARASYMPATHETIC

1.HEART(BV)

3.LUNGS(AIRWAY)

4.EYES

5.G.I

NEUROLOGIC DISORDERS
PERIPHERAL NERVOUS SYSTEM
ORGAN SYSTEM SYMPATHETIC PARASYMPATHETIC
6.G.U

7.SKIN AND SWEAT

8.SECRETIONS:
GASTRIC AND
SALIVARY

9.LIVER

NEUROLOGIC DISORDERS
INCREASE ICP
(INTRACRANIAL PRESSURE)

NEUROLOGIC DISORDERS
INCREASE ICP
(INTRACRANIAL PRESSURE)
Main Problem Increase Bulk of the Brain
Signs and Restlessness-initial sign of increase
Symptoms: ICP
Headache
N/V-pressure at the medulla
oblongata(vomiting may be projectile)
Altered LOC
Diplopia(double vision)-due to pressure
on cranial nerve V1(Abducens)
Cushings Triad
NEUROLOGIC DISORDERS
INCREASE ICP
(INTRACRANIAL PRESSURE)

Signs and  Hypo or Hyperthermia


Symptoms:  Anisocuria(unequal pupil)
 Pinpoint pupil
 Fixed,dilated pupils
 Papilledema
 Dolls eye sign
 Decortication(abnormal flexion)
 Decerebration(abnormal extension)

NEUROLOGIC DISORDERS
INCREASE ICP
(INTRACRANIAL PRESSURE)

NEUROLOGIC DISORDERS
INCREASE ICP
(INTRACRANIAL PRESSURE)
MANAGEMENT:
1.Reduce ICP:
Position:Semi Fowlers
Avoid Factors that Increase ICP:
-Straining/Valsalva Manuever
-Bending on Waist
-Coughing/Sneezing
-Heavy lifting
2.Treat Cerebral Hypoxia
 Oxygen Therapy

NEUROLOGIC DISORDERS
INCREASE ICP
(INTRACRANIAL PRESSURE)
MANAGEMENT:
3.Medications
 Diuretics
-Mannitol(osmotic diuretic)
-Furosemide(loop diuretic)
Anti-Inflammatory(Steroids)
-Decadron(Dexamethasone)

NEUROLOGIC DISORDERS
Q AND A:INCREASE ICP
Tissue plasminogen activator (t-PA) is considered
for treatment of a patient who arrives in the
emergency department following onset of symptoms
of myocardial infarction. Which of the following is a
contraindication for treatment with t-PA?
a.Worsening chest pain that began earlier in the
evening.
b.History of cerebral hemorrhage.
c.History of prior myocardial infarction.
d.Hypertension.

NEUROLOGIC DISORDERS
Q AND A:INCREASE ICP

ANSWER:B :

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)
Main Problem  Disruption of blood and oxygen supply
to the brain tissue.
Commonly  Middle Cerebral Artery(MCA)
affected site:
Risk Factors:  Smoking
 HPN/Heart Problem
 DM
 Family History
 Aneurysm
 Atherosclerosis
NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)
TYPES: CAUSES
1.ISCHEMIC STROKE
 Thrombotic
 Embolic
2.TIA-Transient Ischemic
CLOT
Attach
3.HEMORRHAGIC -RUPTURED ANEURYSM
STROKE Common cause:HYPERTENSION
Diagnostic Exam:
 CT SCAN/MRI
 TPA(for ischemic
stroke only)

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)
SIGNS AND SYMPTOMS:
F-acial Drooping
A-rm weakness/numbness(hemiparesis/plegia)
S-lurred Speech
A-phasia(Receptive and Expressive)
H-emianopsia(loss of half of visual fields)
I-ncrease ICP

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)
Left CVA Right CVA
Right Hemiplegia Left hemiplegia
Right visual defect Left visual field defect
Aphasia Spatial-perceptual field defect
Altered intellectual Increased distractability(poor
activity attention span)
Slow,cautious Impulsive behaviour,poor
behavior judgement, lack of awareness
of deficit

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)
Management for ICP Care for Hemianopsia

VS and LOC(GCS) Approach:unaffected side


Oxygen of visual field
Mannitol Scanning Technique
Dexamethasone
Anticonvulsant
Seizure Precautions

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)
Supportive care Care for Aphasia

Nutrition(TPN,enteral Short Phrases, simple


feedings) details
Activity(Turning,PROM) Use Gestures
 Elimination( I and O ) Ask question one at a
time
 Rehabilitation of the Communication
client Response Board(paper)

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)
Thalamic Syndrome
 Divert/Distract

NEUROLOGIC DISORDERS
CEREBROVASCULAR ACCIDENT
(CVA/STROKE)

NEUROLOGIC DISORDERS
Q AND A:(CVA/STROKE)
A 61 year old male client is admitted to the hospital with
a right sided CVA.The nurse is aware that the most
common cause of the CVA is thrombosis.The nurse
provides instruction to the family about the
homonymous hemianopsia.The nurse should instruct
the client on measures to overcome the deficit by:
a.Place his personal items or object in his impaired
field of vision
b.Approach the client to affected to turn the head to
scan the lost visual field
c.Remind the client to turn the head to scan the lost of
visual field
d.Stop the client from wearing eye glasses
NEUROLOGIC DISORDERS
Q AND A:(CVA/STROKE)

ANSWER:C

NEUROLOGIC DISORDERS
Q AND A:(CVA/STROKE)

A 61 year old male client is admitted to the


hospital with a right sided CVA.The nurse is
aware that the most common cause of CVA is:
a.Embolism
b.Hemorrhage
c.Cerebral arterial spasm
d.Thrombosis

NEUROLOGIC DISORDERS
Q AND A:(CVA/STROKE)

ANSWER:D

NEUROLOGIC DISORDERS
SEIZURE DISORDERS

NEUROLOGIC DISORDERS
SEIZURE DISORDERS
STAGES CHARACTERISTIC TIME/DAY
S
1.PRODROMAL  Symptoms prior to  Few days before seizure
seizure(days
before seizure)
2.AURA  Warning signs  Seconds or min before
before seizure seizure

3.ICTUS  Actual Seizure  1-3 mins(time?)


 5 mins and above(status
epilepticus-emergency)
4.POST ICTUS  After  Hours or days(tonic
seizure/recovery clonic)
 Immediate(absence)
NEUROLOGIC DISORDERS
SEIZURE DISORDERS
TYPES CHARACTERISTICS TIME
1.GENERALIZED SIZURE
(whole brain)
a.Tonic-  Most common  1-3 mins(timer)
Clonic  (+) Aura  5 mins and above(status
(grand mal) epilepticus-emergency
reponse)

b.Absence  Common:Pedia  Seconds


(Petit-Mal)  Hallmark:Staring

c.Atonic  Without Muscle  Immediate


(Drop Attack) Tone(standing
suddenly fall)Px:Head

NEUROLOGIC DISORDERS
SEIZURE DISORDERS
TYPES CHARACTERISTICS TIME
2.FOCAL SIZURE
(partial/specific area of the brain)
Other Name: Jacksonian Seizure

a.Simple Partial Patient is aware Less than


(Focal Onset Aware) (+) Aura 2 mins

b.Complex Partial Unaware


(Focal Impaired Automatism(lip
Awareness) smacking)

NEUROLOGIC DISORDERS
SEIZURE DISORDERS

OTHER TYPES OF SEIZURE


 Psychomotor Seizure
Febrile Seizure
-common under 5 yr.old
Status Epilepticus

NEUROLOGIC DISORDERS
SEIZURE DISORDERS
DIAGNOSTIC TEST:
1.EEG
Preparation:
 Wash the hair (before and after)-to remove
oils/sprays, paste.
 avoid stimulants, depressants(24hrs)

NEUROLOGIC DISORDERS
SEIZURE DISORDERS
MANAGEMENT:SEIZURE PRECAUTIONS
1.SAFETY:
oxygen /suction
padded bedrails
bed lowest position
pillow
remove restrictive clothing
2.DURING SEIZURE
Lay down with pillow under head/lap
Do not restrain
Do not insert anything in the mouth
Time seizure
Note characteristics/NEURO assessment
NEUROLOGIC DISORDERS
SEIZURE DISORDERS
MANAGEMENT:SEIZURE PRECAUTIONS
3.MEDICATION:
Anticonvulsants:
 Barbiturates(Phenobarbital
Action:Stimulates GABA receptors
 Hydantoins:Phenytoin/Dilantin
S/E:Ginigival Hyperplasia
NI:Oral care
C.I:No to antacids/milk(decrease absorption)
 Diazepam or Lorazepam(fast acting for status
epilepticus)
S/E:Very Drowsy,TOLERANCE(not as effective)

NEUROLOGIC DISORDERS
Q AND A:SEIZURE DISORDERS

A client is experiencing the tonic phase of


the grandma seizure.After protecting the
clients head,which of the following is the
nurse expected to do first?
a.Monitor VS especially the RR
b.Place a padded tongue blade in the
pateinst mouth
c.Provide mechanical ventilation
d.Turn patient to his side

NEUROLOGIC DISORDERS
Q AND A:SEIZURE DISORDERS

ANSWER: D

NEUROLOGIC DISORDERS
HEAD TRAUMA

NEUROLOGIC DISORDERS
HEAD TRAUMA
Concussion-jarring of the brain
Contusion-bruising of the brain tissue
SIGNS AND SYMPTOMS:
Signs of Basilar Head Injury:
-Battles sign(post auricular ecchymosis-at the mastoid
process behind the ear)
-Raccoon Eyes-peri orbital ecchymosis
-Rhinorrhea and Otorrhea
-Increase ICP

Note:CSF leak causes high risk for meningitis


NEUROLOGIC DISORDERS
HEAD TRAUMA

NEUROLOGIC DISORDERS
HEAD TRAUMA

NEUROLOGIC DISORDERS
HEAD TRAUMA
MANAGEMENT:
Manage Increased ICP
 Monitor CSF leak(test the fluid for glucose)
Material: Gauze pad
Result:(+ )CSF Leak:Halo or ring sign-yellowish ring
encircles the blood.

NEUROLOGIC DISORDERS
HEAD TRAUMA

NEUROLOGIC DISORDERS
HEAD TRAUMA
SURGERY:
1.Burr Hole(Trephine)
2.Craniotomy
3.Craniectomy
4.Cranioplasty

NEUROLOGIC DISORDERS
HEAD TRAUMA

NEUROLOGIC DISORDERS
HEAD TRAUMA

NEUROLOGIC DISORDERS
Q AND A:HEAD TRAUMA
A patient has returned to the neurosurgery unit after
her craniotomy operation.Which of the following orders
in the chart the nurse question?Select all that apply.
1.Administer oxygen at 2lpm
2.Give dexamethasone 4mg every 6 hours
3.Infuse IVF at 150ml/hr
4.Place the head in flexion
5.Elevate the head of the bed at 30 degrees
6.Encourage visitors for the client
7.Do some exercise like head rotation
8.Give stool softener as ordered

NEUROLOGIC DISORDERS
Q AND A:HEAD TRAUMA

ANSWER:3,4,6,7,

NEUROLOGIC DISORDERS
MENINGITIS

NEUROLOGIC DISORDERS
MENINGITIS
CHARACTERISTIC Inflammation of the
Meninges(Covering layer of the
brain)
CAUSES: BACTERIAL:
 Streptococcus pneumonia
 Neisseria Meningitides
VIRAL:
 Enteroviruses(most common –
spread through respiratory
secretions)
 Arboviruses
 HIV
 Herpes simplex virus
NEUROLOGIC DISORDERS
MENINGITIS
DIAGNOSTIC TEST:
Lumbar culture
Specimen:CSF
Normal:
Glucose:50-80mg/dl(decreased-infection)
Protein-20-50mg/dl(increased-infection)
Pressure-75-180mmH2O or 0-14mmhg
Result:
CSF glucose –decreased
CSF protein- elevated
CSF Color :turbid/purulent

NEUROLOGIC DISORDERS
MENINGITIS
SIGNS AND SYMPTOMS:
Nuchal rigidity(neck stiffnes)
Kernigs sign
Brudzinskis sign
Flu like Symptoms
Increased ICP

NEUROLOGIC DISORDERS
MENINGITIS

NEUROLOGIC DISORDERS
MENINGITIS
MANAGEMENT:
1.Prevent Transmission: DROPLET precautions
2.Non Stimulating Environment
Bed rest
Darkened room
Cool cloth over the eyes
3.Seizure Precautions
4.Manage the ICP
5.Medications:
 Antibiotics IV(ampicillin, penicillin, cephalosphorins)
Codeine for headache
Acetaminophen or aspirin-fever NEUROLOGIC DISORDERS
Q AND A:MENINGITIS
The nurse receives a report at the beginning of a shift
about a client with suspected Meningitis.Which
assessment data on the client, the nurse expects to
find: Select all that Apply.
1.Opisthotonus Posture
2.Brudzinskis Sign
3.Episodes of seizure
4.Hydrocephalus
5.Herberdens nodules
6.Kernigs sign
7.Exophtalmus
8.Photophobia
9.Nuchal Rigidity NEUROLOGIC DISORDERS
Q AND A:MENINGITIS

ANSWER:1,2,3,4,6,8,9

NEUROLOGIC DISORDERS
SPINAL CORD INJURY

NEUROLOGIC DISORDERS
SPINAL CORD INJURY
CAUSE: Trauma
EFFECTS: Paralysis
Loss of :
-Reflexes
-Sensory function(afferent fibers
involved)
-Motor function(efferent fibers
involved)
Autonomic dysfunction
NEUROLOGIC DISORDERS
SPINAL CORD INJURY(SCI)
SIGNS AND SYMPTOMS:
CERVICAL SCI-most fatal THORACIC SCI
 Quadriplegia  Paraplegia
 Respiratory Paralysis  Poor control of upper
trunk
 Bowel and Bladder  Bowel/Bladder retention
Retention
Complication:
Autonomic Dysreflexia
-Injury above T6

NEUROLOGIC DISORDERS
SPINAL CORD INJURY(SCI)
SIGNS AND SYMPTOMS:
LUMBAR SCI SACRAL SCI
 Paradriplegia If Injury is above S2:
 Bowel and Bladder  (+) Erection
Retention  (-) Ejaculation
If injury is between S2-S4:
 (-) Erection
 (-) Ejaculation
 Paraplegia:
Male:Impotence
Female:(-) Orgasm,but capable to
bear a child
 .B and B Incontinence
NEUROLOGIC DISORDERS
SPINAL CORD INJURY(SCI)
COMPLICATIONS:
1.SPINAL SHOCK 2.AUTONOMIC
DYSREFLEXIA
Complete Loss of ALL Hyperstimulation of SNS
reflexes
Flaccid Paralysis DOC:
1.Hexamethonium
Chloride(a ganglionic
blocking agent)
2.Nitroprusside(vasodilator)

NEUROLOGIC DISORDERS
Q AND A:SCI
A client is being assessed by a nurse in the
emergency after suffering from a driving accident 3
hours earlier. It was revealed that the client ahs
fracture of the C4.Although the client is breathing
independently ,he has no muscle tone and no
movement below the area of injury. The nurse
recognizes and is aware that the client:
a.Will have paralysis in all 4 extremities
b.Has been suffering a complete SCI
c.Is going through a spinal shock
d.Ha sustained an upper motor neuron injury

NEUROLOGIC DISORDERS
Q AND A:SCI

ANSWER:C

NEUROLOGIC DISORDERS
Q AND A:SCI
The dietitian has recommended a client with SCI to
decrease the total intake of calcium per day.When the
client ask the nurse about it,which of the following
responses would give the most accurate information?
a.”Dairy products would probably contribute to weight
gain”
b.”Excessive dairy products intakes makes
constipation more common”.
c.”Immobility promotes calcium absorption from
intestines”
d.”Bone demineralization will occur due to lack of
weight bearing”.
NEUROLOGIC DISORDERS
Q AND A:SCI

ANSWER:D

NEUROLOGIC DISORDERS
PARKINSONS DISEASE

NEUROLOGIC DISORDERS
NEUROTRANSMITTERS
Excitatory Inhibitory
Acetylcholine GABA(Gamma Amminobutyric
Acid)

Dopamine Glycine

Glutamate

Norepinephrine
Serotonin

NEUROLOGIC DISORDERS
PARKINSONS DISEASE
CHARACTERISTIC:

PROBLEM:  Decrease Dopamine


 Imbalance between Dopamine vs
Acetylcholine
ETIOLOGY/RISK  Unknown
FACTORS  Older(60)
 Trauma

NEUROLOGIC DISORDERS
PARKINSONS DISEASE
SIGNS AND SYMPTOMS
1.Tremors(initial sign)
Pill-rolling tremors
2.Cogwheel rigidity
3.Bradykinesia/Akinesia
4.Other Symptoms:
Shuffling, festinating gait- tip toe walking
Flattened affect(mask like facial expression)
Stooped posture
Monotonous voice
Dysphagia/Fatigue NEUROLOGIC DISORDERS
PARKINSONS DISEASE
MANAGEMENT:
1. SAFETY-Priority
Soft diet for dysphagia
Firm bed to prevent contractures
Upright Position-prevent aspiration
Increase fluid intake
2.MEDICATIONS:
1.Dopaminergic
DOC:Carbidopa with levodopa(Sinemet)
Levodopa-a precursor of dopamine can cross the BBB
Carbidopa- reduces destruction of levodopa.
Note: Dopamine cannot cross the BBB
NLE Tips(AVOID):
 Vit.B6(Pyrodoxine)-it decrease effect of drugs
NEUROLOGIC DISORDERS
PARKINSONS DISEASE
2.Dopamine Agonist 3.MAOI-B

Action:stimulates Action:Increase dopamine


dopamine receptors by stopping MAO Activity
Parlodel(Bromocriptine Rasagiline(Azilect)
Mesylate)

NEUROLOGIC DISORDERS
PARKINSONS DISEASE
4.Anticholinergics 5.Antiviral Drugs
Action: Action:
to reduce rigidity stimulates dopaminergic
activity in CNS
Artane(Trihexyphenidyl) Symmetrel(Amantadine
Cogentin(Benztropine) Hcl)
Akineton(Biperiden)
S/E:Dry Mouth/Urinary
Retention
C.I:Glaucoma-increase IOP
NI:Sugar less candy,ice chips
-Encourage to Void

NEUROLOGIC DISORDERS
Q AND A:PARKINSONS DISEASE

Which of the following is the common


early sign of Parkinson's disease as
gathered by the nurse conducting the
history?
a.Gait Changes
b.Slow Movement
c.Freezing movement
d.Tremors in one of the upper limbs

NEUROLOGIC DISORDERS
Q AND A:PARKINSONS DISEASE

ANSWER:D

NEUROLOGIC DISORDERS
NEUROMUSCULAR DISORDERS

NEUROLOGIC DISORDERS
NEUROMUSCULAR DISORDERS
DISORDERS PROBLEM BULBAR COMMON
SIGNS SYMPTOMS
1.MG

2.GBS

3.MS

4.ALS

NEUROLOGIC DISORDERS
NEUROMUSCULAR DISORDERS
DISORDERS PATTERN COMMON DOC:
OF SYMPTOM
PARALYSIS S
1.MG

2.GBS

3.MS

4.ALS

NEUROLOGIC DISORDERS
MG VS.GBS

NEUROLOGIC DISORDERS
NEURONS
Neuron
-basic structural and functional unit of nervous system

NEUROLOGIC DISORDERS
NEURONS-MUSCLE

NEUROLOGIC DISORDERS
NEURONS-NEURONS

NEUROLOGIC DISORDERS
HOW DOES MG DEVELOP?

NEUROLOGIC DISORDERS
HOW DOES MG DEVELOP?

NEUROLOGIC DISORDERS
NEUROTRANSMITTER

Note: Transmission across synapse is


essentially a chemical process .
Synaptic transmission is both excitatory
or inhibitory.

NEUROLOGIC DISORDERS
MG VS.GBS
MYASTHENIA CHARACTER GUILLAINE BARRE
GRAVIS(MG) ISTICS SYNDROME(GBS)
Decrease MAIN Damage Myelin Sheath of
Acetylcholine PROBLEM PNS Neurons
Autoimmune ETIOLOGY  Autoimmune
 G-I Infection
(Campylobacter
Infection)
 R-espi Infection(Swine
Flu)
 E-PSTEIN BARR
Virus/HIV

NEUROLOGIC DISORDERS
MG VS.GBS
MYASTHENIA CHARACTER GUILLAINE BARRE
GRAVIS(MG) ISTICS SYNDROME(GBS)
SIGNS/
 Ptosis SYMPTOMS  Paresthesia/Numbness
 Dysphagia (feet)
 Dysarthria  Dysphagia/Constipation
 Dyspnea  Dyspnea
 Fatigue  Speech Problem
 Snarl  ANS:Cardiac dysrhythmias
smile(mask like)  Elevated protein level in
the CSF

Muscle Weakness MAIN Muscle Weakness


PROBLEM

NEUROLOGIC DISORDERS
MG VS.GBS
MYASTHENIA CHARACTERI GUILLAINE BARRE
GRAVIS(MG) STICS SYNDROME(GBS)
DESCENDING PARALYSIS ASCENDING

AIRWAY- PRIORITY AIRWAY-Respiratory


Respiratory Failure
Failure

Myasthenic COMPLICATION
Crisis
Cholinergic
Crisis
NEUROLOGIC DISORDERS
MG VS.GBS
MYASTHENIA GUILLAINE BARRE
GRAVIS(MG) SYNDROME(GBS)
1.Tensilon Test D 1.EMG(Electromyography)
(Endrophonium Test) I 2.Lumbar Puncture
 short acting A NI:
cholinergic G Before:Empty the bladder
 Dose:2mg first then N During:Lateral
8mg-IV O Recumbent(knees-up to
 Result(+)-improve in S abdomen/chin to chest)
muscle strength(only T After:Flat
for 3-5 mins) I Increase OFI
C Result:
Protein-Increase
WBC-Normal
NEUROLOGIC DISORDERS
MG VS.GBS
MYASTHENIA GRAVIS(MG) GUILLAINE BARRE
SYNDROME(GBS)
MANAGEMENT:
1.Improve Swallowing: 1.Symptomatic
Gag reflex /Supportive Management
Meds: 20-30 mins before
Cold Beverage 2.Promote adequate
2.Promote adequate ventilation
ventilation
3.Avoid trigger(infections) 3.Bed Side :Intubation
4.Rest Set/MV/Suction(acute
satge)

NEUROLOGIC DISORDERS
MEDICAL MANAGEMENT:
MG VS.GBS
1.Acetylcholinesterase 1.Immunoglobulin Therapy
Inhibitors/Cholinesteras Action:from donor-to STOP
e Inhibitors antibodies that are damaging
Prostegmin(Neostigmine) the nerves
Mestinon(Pyridostigmine) 2.Plasmapahresis
Best Time:Before Meals Action: remove antibodies
(better absorption) that are attacking the myelin
NLE Tip: sheath
 Observe for signs of
cholinergic and
myesthenic crisis
 Antidote:Atrophine

NEUROLOGIC DISORDERS
MG VS.GBS
MYASTHENIA GUILLAINE BARRE
GRAVIS(MG) SYNDROME(GBS)
MEDICAL MANAGEMENT:
2.Glucocorticoids
3. Plasmapharesis
4.Thymectomy

NEUROLOGIC DISORDERS
Myasthenic Crisis Cholinergic Crisis(PNS)
MG VS.GBS
-undermedication/delayed -excessive medications
medication S/Sx:
S/Sx:  LIKE:PARASYMPATHETIC
 LIKE:SYMPHATETIC STIMULATION
STIMULATION  BP(Decrease)
 BP(Increase)  HR(Decrease)
 HR(Increase)  Increase secretions:
 Severe Muscle Weakness:  Sweating/lacrimation
 (-)Gag/Cough/Swallowing  Diarrhea/Abd.cramps
Reflex  Severe Muscle Weakness:
 Respiratory failure  Dysphagia, chewing/speakin
 Bowel or bladder incontinence  Respiratory Failure
Interventions: Interventions:
DOC:Acetylcholinestaerase DOC:Atrophine 1mg IV
Inhibitor/Cholinergic D/C Cholinergic drugs
Drugs(Neostigmine) Provide adequate ventilator
Provide adequate ventilator support
support NEUROLOGIC DISORDERS
MG VS.GBS

QUESTION: HOW WILL YOU KNOW IF THE PATIENT


IS EXPERIENCING MYASTHENIC CRISIS OR
CHOLINERGIC CRISIS?

NEUROLOGIC DISORDERS
Q AND A:MG

A client is diagnosed with MG is given an


anticholinesterase drug therapy. This is to
distinguish cholinergic crisis from myasthenic
crisis.Which of the following symptoms is not
present in cholinergic crisis?

a.Improved muscle strength after tensilon injection


b.Increased Weakness
c.Diarrhea
d.Increased Salivation

NEUROLOGIC DISORDERS
Q AND A:MG

ANSWER:A

NEUROLOGIC DISORDERS
Q AND A:GBS
The pediatric ward nurse ask the client who ahs
GBS to cough every now and then.She also
assesses clients speech for decreased muscle
volume and clarity.Which of the following is the
underlying rationale for doing those two
assessments?
a.To determine regression to an earlier
developmental phase
b.To deteremine increase ICP
c.To determine involvement of facial and cranial
nerves
d.To determine inflammation of larynx and epiglotis
NEUROLOGIC DISORDERS
Q AND A:GBS

ANSWER:C

NEUROLOGIC DISORDERS
MULTIPLE SCLEROSIS(MS)

NEUROLOGIC DISORDERS
MULTIPLE SCLEROSIS(MS)
MULTIPLE SCLEROSIS(MS)=MYELIN SHEATH(MS)
Characteristic: Damage Myelin Sheath of
CNS/PNS Neurons

ETIOLOGY: UNKNOWN
Autoimmune
RISK FACTORS: Women(20-40 years old)
EBV
DIAGNOSTIC TEST: MRI
Lumbar Puncture
Result:(+)Oligoclonal
bands(protein)Increase
Indication:Inflammation
NEUROLOGIC DISORDERS
MULTIPLE SCLEROSIS(MS)
SIGNS AND SYMPTOMS
Ataxic Gait(Uncoordinated Movement)
+Romberg Signs(cerebral lesion)
Lhermittes Sign(Electric Shock Sensation)
Vision:Blurry,double vision
Elimination:Incontinence or Retention
Emotions:Fatigue,depressed mood
 Charcoats Triad:
S-canning Speech(repetition the first syllable of each word)
I-ntention tremors
N-ystagmus

NEUROLOGIC DISORDERS
MULTIPLE SCLEROSIS(MS)
MANAGEMENT:
PRIORITY:SAFETY
Patch the eye alternately -diplopia
 Diet-high in fiber,fluids
 Avoid hot baths(heat increases weakness)
 Speech and PT

NEUROLOGIC DISORDERS
MULTIPLE SCLEROSIS(MS)
MEDICATIONS:
1.STEROIDS:
 Prednisone
2.BLADDER ISSUES
 Anti Cholinergic:Oxybutynin(Incontinence)
 Cholinergic:Bethanecol(Retention)
3.FATIGUE
 Amantadine
 Modafinil:CNS Stimulant
4.SPASM
 Baclofen
 Diazepam
NEUROLOGIC DISORDERS
MULTIPLE SCLEROSIS(MS)
MEDICATIONS
5.TREMORS:
Propanolol
Isoniazid(Infection related tremors)

NEUROLOGIC DISORDERS
Q AND A:MS
A client is given health teaching by the nurse
regarding the management of MS.Which of the
following instructions should be included in the care
plan?Select all that apply.
1.Take daytime rest /naps
2.Avoid eating vegetables and fruits
3.Avoid hot baths or showers
4.Set a regular time for elimination
5.Limit fluid intake to 1l/day
6.Eat a diet high in fiber like papaya and pineapple
7.Elevate the toilet seat for easy access
8.Space out drinking fluids
NEUROLOGIC DISORDERS
Q AND A:MS

ANSWER: 1,3,4,6,7,8

NEUROLOGIC DISORDERS
AMYOTROPHIC LATERAL
SCLEROSIS(ALS)

NEUROLOGIC DISORDERS
AMYOTROPHIC LATERAL
SCLEROSIS(ALS)
Characteristic: Degeneration of Motor Neuron
Increase glutamate
OTHER NAME: Lou Gehrigs Disease

ETIOLOGY: UNKNOWN

RISK Family History/Genetics


FACTORS: (2-3 out of 100,000 individuals)

NEUROLOGIC DISORDERS
AMYOTROPHIC LATERAL
SCLEROSIS(ALS)
SIGNS/SYMPTOMS:
Dysphagia(1st sign-initial sign)

Dysarthria
Spasticity
Fasciculations(twitching)
Muscle weakness and atrophy
Respiratory difficulty

NEUROLOGIC DISORDERS
AMYOTROPHIC LATERAL
SCLEROSIS(ALS)
MANAGEMENT
Supportive and Symptomatic
Promote respiratory function
Gastrostomy feeding
Avoid aspiration
Assist with ADL
Provide emotional support to the client and family

 Medication:
RILUZOLE(Glutamate Antagonist)
Action:Inhibit Glutamate Release
 Slow progression of disease
NEUROLOGIC DISORDERS
Q AND A:ALS
A client is suspected with Amyotrophic Lateral
Sclerosis which is a debilitating disease. Which of the
following assessment findings does the nurse expect.
Select all that apply.
1.RR of 45
2.Dysarthria
3.Tremors when resting
4.Drooping of the eyelids
5.Weakness of the extremities
6.Substantial Memory loss
7.Facial Fasciculation
8.Fatigue while talking
NEUROLOGIC DISORDERS
Q AND A:ALS

ANSWER: 1,2,5,7,8

NEUROLOGIC DISORDERS
BELLS PALSY
VS.
TRIGEMINAL NEURALGIA

NEUROLOGIC DISORDERS
BELLS PALSY CHARACT TRIGEMINAL
ERISTICS NEURALGIA
CRANIAL CRANIAL CRANIAL NERVE 5
NERVE 7 NERVES -SENSORY NERVE
-MOTOR AFFECTED
NERVE
 Infection(herp ETIOLOGY  CNS Problem
es near the  Trauma
ear)  Stroke
 Trauma

NEUROLOGIC DISORDERS
BELLS PALSY CHARACTE TRIGEMINAL
RISTICS NEURALGIA
 FACIAL SIGNS/ FACIAL
PARALYSIS: SYMPTOMS PAIN:LIPS,GUMS,NOSE
1 side of FACE Excruciating
 Ptosis Recurrent
 Inability to : Stabbing
 Raise Eyebrow Pain aggravated by:
 Frown,  Cold(washing the face)
 Smile  Chewing
 Close the  Hot or cold foods and
eyelids fluids
 Puff out cheeks  Touch of wind on the
face.

NEUROLOGIC DISORDERS
BELLS PALSY MANAGEMEN TRIGEMINAL
T
NEURALGIA
1.Facial N Avoid TRIGGERS:
exercises U 1. hot or cold
2.Protect the R foods/beverages
eyes from S 2. liquid and soft foods
dryness I 3.Chewing: unaffected
3.Chewing: N side
unaffected side G

INTERVENT
IONS

NEUROLOGIC DISORDERS
BELLS PALSY MANAGEME TRIGEMINAL
NT NEURALGIA
1.Steroids MEDICAL 1.Lioresal(Baclofen)
2.Analgesics 2.Valium(Diazepam)

SURGERY 1.Alcohol injection of


the nerve
2.Neurectomy

NEUROLOGIC DISORDERS
ALZHEIMERS DISEASE

NEUROLOGIC DISORDERS
ALZHEIMERS DISEASE
CHARACTERISTIC:  degenerative disorder of the cerebral
cortex resulting to microscopic
plaques.
 Progressive loss of memory
 5th leading cause of death among
adult 65 and above

ETIOLOGY:  UNKNOWN
RISK FACTORS:  Age
 Heredity
PROBLEM:  MEMORY LOSS:
Recent Memory(1st)
Remote Memory(Intact)
 CONFUSION
NEUROLOGIC DISORDERS
ALZHEIMERS DISEASE
MANAGEMENT:
 Prevent  Orient
Injury  Close supervision
(safety is the  Remove hazards(toxic
priority) drugs ,dangerous electrical appliance)
Promote  Exercise:walking with an escort
Activity  Mental Stimulation:
 Listening to music, coloring, watching
TV
 Simple games or activities

NEUROLOGIC DISORDERS
ALZHEIMERS DISEASE
MANAGEMENT
 Promote Sleep  Wander in a safe place until
he/she becomes tired
 Prevent shadows in the room
 Avoid Agitation  Avoid scolding, embarrassing,
and Violence arguing
 Approach the client slowly and
calmly
 Remove from stressful
environment

NEUROLOGIC DISORDERS
ALZHEIMERS DISEASE
MANAGEMENT
Minimize  Call the client by name
confusion and  Orient the client frequently
Disorientation  Ask only one question at a time
 Place a calendar and clock in a
visible place
 Provide structured/ROUTINE
activities
 Allow the client to reminisce
(remote memory may remain intact
for a long period of time)
 Allow time for the client to
complete a task

NEUROLOGIC DISORDERS
ALZHEIMERS DISEASE
MANAGEMENT
 Prevent Sundown  Turn lights on before it becomes dark
Syndrome

 MEDICATION 1.Acetylcholinesterase Inhibitors:


 Aricept
 Razadyne
 Tacrine
 DR.G
1.D-onepezil
2.R-ivastigmine
3.G-alantamine
2.NMDA(N-Methyl D-aspartate)
 Namenda

NEUROLOGIC DISORDERS
Q AND A:ALZHEIMERS DISEASE
A patient with Alzheimers disease has a self care
deficit linked to his cognitive impairement.Which is a
priority to include in the nursing care plan for a
patient who is experiencing difficulty processing and
completing complex task?
a.Repeating the instructions until the patients follow
them
b.Requesting the patient to do one step of the task at
a time
c.Demonstrating on how to do for the patient
d.Maintaining structure and routine for the patient

NEUROLOGIC DISORDERS
Q AND A:ALZHEIMERS DISEASE

ANSWER:B

NEUROLOGIC DISORDERS
Q AND A:ALZHEIMERS DISEASE
Alzheimer’s disease is the secondary diagnosis of a
client admitted with myocardial infarction. Which
nursing intervention should appear on this client’s
plan of care?
a.Perform activities of daily living for the client to
decease frustration.
b.Provide a stimulating environment.
c.Establish and maintain a routine.
d. Try to reason with the client as much as possible.

NEUROLOGIC DISORDERS
Q AND A:ALZHEIMERS DISEASE

ANSWER:C

NEUROLOGIC DISORDERS

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