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Acute Flaccid Paralysis
Acute Flaccid Paralysis
PARALYSIS
ACUTE FLACCID PARALYSIS
In the Global Polio Eradication Initiative, AFP is defined as any case of AFP in
children <15 year old or any paralytic illness at any age when polio is
suspected.
COMMON CAUSES OF AFP:
GUILLAIN-BARRE SYNDROME
TRANSVERSE MYELITIS
TRAUMATIC NEURITIS
POST DIPHTHERIC NEUROPATHY
NON POLIO ENTEROVIRAL ILLNESSES
ACUTE FLACCID PARALYSIS SURVEILLANCE
● All patients with AFP within the last six months should be reported to the
Surveillance Medical Officer of the World Health Organisation.
This excretion is maximum just before the paralysis and during the first 2 weeks
after the onset of paralysis.
From the intestines, the virus travels to the regional lymph nodes and then into the
circulation.
The virus infects the nervous system via nerves or blood stream.
CLASSIFICATION
CLASSIFICATION CLINICAL FEATURES
Phase Treatment
1. Infections :
● Viral infections-EBV(infectious mononucleosis), measles, mumps, rubella,
varicella, cytomegalovirus, influenza, hepatitis B, hepatitis A, HIV
● Bacterial infections-Campylobacter jejuni, brucellosis
2. Systemic lupus erythematosus
3. Hodgkins disease
4. Sarcoidosis
5. Immunosuppression
6. Rabies vaccine
PATHOGENESIS
● Immunological reaction due to hypersensitivity. It is directed against the
myelin sheath of the peripheral nerves.