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PHMD 451: ACUTE RESPIRATORY

SYNDROME
ACUTE RESPIRATORY SYNDROME

Acknowledgement/Source:

https://www.slideshare.net/NorthTecNursing/ards-overview
• Drugs cocaine, aspirin
Destruction of type I *
Type II pneumocytes
WOB – work of breathing
PEEP – Positive end
expiratory pressure
SUMMARY OF TREATMENT

• Supplemental O2
• Supportive therapy:
 Sedation (increase tolerance to mechanical ventillation,
reduced oxyden consumption) – lorazepam
• Paralysis if sedation inadequate – neuromuscular blockers
• Opioid – pain relief (morphine/fentanyl
• Fluid management – reduced left atrial and reducing pulnary edema.
Keep CVP(central venous pressure) less <4 mm Hg while maintaing
adequate organ perfusion. – Fluid restriction and diuretics
• Nutrional support – pts usually in high catabolic state. Enteral feeding
• Glucose control
• DVT/GIT prophylaxis

• TREAT UNDERLYING CAUSE:


• Surfactant/anti-oxidants?? – no evidence of efficacy
• NO, PGI2, PGE2 – no improvement in outcomes
• Glucocorticoids - <2weeks uncertain; >2weeks harmful
• Human mesenchymal stem cell – looks promising
THANK YOU

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