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8-Cardiovascular Disorders-2
8-Cardiovascular Disorders-2
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Disorders
Atheroma
Patchy changes develop in the tunica intima of
large & medium-sized arteries
The deposits consist of:
Cholesterol
Lipids compounds
Smooth muscle& Fat filled monocytes
Accumulation of fibrous plaques & lipids
progressively narrow the lumen & impedes blood
flow to the myocardium (Atherosclerosis).
Predisposing Factors
Family
Diet & Alcohol Life style
History
Smoking
Arteriosclerosis
Large & medium arteries Small arteries &
Infiltration of tunica arterioles
media Hyaline thickening of
Fibrous tissue & tunica media & intima
calcium Lumen narrowing
Loss of elasticity & peripheral resistance
dilation & BP
Systolic & pulse Ischemia
pressure gangrene
Sings & Symptoms