Mixing of Capsules

Introduction
Mix UP
Mix up can be defined as taking something which is not subject to take; taking on thing
to another. Taking wrong item unintentionally which can be easily identified such as
missing of different color or different sizes capsules. Mix up is:
• Assume wrong item to right thing.
• Failure to take action on due time.
• Mixture of various item/elements.
• Selection of wrong item.
• Selection similar product/material/item.
• Unintentionally taking one thing to another.
• Wrong selection of desired material.
• Wrong action taken due to lack of attention.
 Causes of Mix Up
Following are the some probable cause of mix up:
• Breakdown of processing equipment.
• Collation/Procure similar packaging/printed material form same vendor.
• Engaging untrained/partial trained personnel.
• Engaging single operator to multiple lines.
• Failure to follow written procedure for line clearance.
• Inappropriate labelling.
• Improper segregation of product/item during manufacturing operation.
• Manual operation other than automated system.
• Rejection material handling.
• System failure.
 Contamination
Definition:
Contamination can be defined as the presence of undesirable element,
impurity or constituent which infects, corrupts, spoils, makes
substandard or make unhealthy a factory, normal environment, physical
body, material, process steps, bulk, liquid, granules, solid etc.
Types of Contamination
Non-Viable
Liquid or solid particulate contamination range from 001 and 1000
microns such as smoke, dust, fogs, fumes and mists.
Viable.
Particulate contamination that supports or consists of one or more live
microorganisms such as viruses, Bacteria & Spores.
 Sources of Contamination
Following are the main sources of contamination:
• Atmosphere
• Clothing
• Equipment
• Fluid
• HVAC System
• Manufacturing debris
• Premises
• People
• Processing operations
• Surfaces
• Utilities & services
 How to avoid mix up
Following are the strategies to avoid mix up:
• Establish and Enforce strict Protocols.
• Practice effective personnel hygiene..
• Utilize personnel protective equipment properly.
• Designate separate workspaces and equipment.
• Trained and educate personnel.
• Product should be physical segregate and labeled with identification labels.
• There should be only one product in area at a time.
Thank you!