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1-Development of Face & Oral Cavity 2
1-Development of Face & Oral Cavity 2
Development of
Face &
Oral cavity
Origin of Facial tissues:
Fertilized ovum - gives rise by series of cell
divisions to Morula.
Morula consists of ‑ Extra embryonic
membranes & Placenta.
Single layer of cells live up to form Embryonic
disc.
Embryonic Disc - by Cell divisions & movements
gives rise to two layered structure with an
intervening space ‑ Upper layer & Lower layers.
Cells of upper layer multiply and migrate &
Occupy the space 3 layers called Germ Layers
Ectoderm, Mesoderm & Endoderm.
Neural plate :
The median strip of mesodermal cells induce
its formation within the ectoderm.
Induction :
- Process that initiates differentiation of
cells.
- After induction cells are independent of
further growth.
- Neural plate further grows and folds itself
into the Neural tube.
- Ectodermal cells at the lateral margins of
neural plate - form the neural crest cells.
Significance of Neural crest cells :
Neural crest cells are also referred to as
the Ectomesenchymal cells.
(Loose embryonic connective tissue)
A – Nasal cavity
B – Oral Cavity
C – Nasal Fin
D – Bucco Nasal
membrane
E – Maxillary Isthmus
380 6 Week of I.U
th
A – Fused Mandibular
Processes.
B – Maxillary Process.
C – Lateral nasal
Process.
D – Median Nasal Proces.
E – Naso Optic furrow.
Development of Palate
Primary Palate :
- The Nasal Pits deepen & develop into Nasal
cavities – separated by the primitive Nasal
Septum.
- The primitive Nasal Cavities are separated
from the oral cavity by Primary Palate.
- Forms roof of anterior portion of primitive oral
cavity.
- Separates oral cavity & nasal cavity.
- Contributes to Upper lip, Anterior maxilla &
Maxillary Prominence & Secondary palate.
- At this stage the Stomodeum is in 2 parts:
- Small oral Cavity – below the Primary
Palate.
- Large Oronasal Cavity.
382 6th week of I.U: Primary
Palate
A – Primitive Nasal
Cavities
B – Primary Nasal
Septum
C – Primary Palate
Secondary Palate
- Out growths from the medial portions of
the maxillary process & the Primary
Palate grow to form the Palatine Shelves
of the secondary palate.
- These shelves are brought to a horizontal
position by a rotational hinge like
movement.
- The Secondary Nasal Septum grows
downwards & Posteriorly from the Primary
Nasal Septum in the midline.
383 6th Week I.U – Secondary
Palate
A – Lateral Palatine
Shelves.
B – Primary Palate.
C – Secondary Nasal
Septum.
384 7th Week of I.U – Sec. Palate
A – Lateral Palatine
Shelves.
B – Developing
Tongue
Initially the developing Tongue fills the
whole of the Oronasal cavity.
The growing Lateral Paplatine shelves grow
downward and laterally to the Tongue.
The Stomodeum enlarges.
Vertically inclined Palatine shelves grow
horizontally.
Later with faster growth & expansion of the
Mandibular arch the Tongue drops down –
allowing the Lateral Palatine Shelves to grow
medially towards each other in the midline to fuse.
The fused Palatine shelves develop the
Secondary Palate.
Behind the Sec. Nasal Septum the Palatine
shelves fuse to form the Soft palate
Secondary palate gives rise to: 2/3 of hard
palate & all of the soft palate.
386
A – Lateral palatine
shelves.
B – Secondary Nasal
Septum.
C – Separating
epithelium.
D – Developing
Maxilla.
Mechanisms Involved in Movement
of
Palatine Shelves
1. Rapid differential Mitotic growth.
2. Variations in blood flow.
3. Intrinsic shelf force.
4. Biochemical changes in the connective
tissue.
5. Reflex Jaw activity.
6. Pressure differences between the Oral &
Nasal cavities.
385 8 Week of I.U
th
A – Lateral Palatine
shelves.
B – Primary Palate.
Ossification of Hard Palate
From Four centres:
One in each developing Maxilla –
approximately above the developing
deciduous Canine tooth Germ.
One in each developing Palatine bone –
situated in the region forming the future
perpendicular plate.
387 Early Ossification of Hard
Palate
A – Body of the
Maxilla.
B – Bone extending
into Palate.
C – Nasal cavity.
Visceral Arches : 6 nos: 5 th rudimentary.
Ist arch : Mandibular arch.
IInd arch : Hyoid arch.
- Ist and IInd arches undergo further development
and meet in the ventral midline by the processes.
- Mesoderm of the Ist and IInd arch give rise to the
Vth & VIIth nerves & musculature.
- Nerve fibers of the V,VII,IX & X cranial nerves
extend into the mesoderm of the first four
visceral arches.
- Crest cells of the visceral arches give rise to
skeletal components such as Meckel's cartilage,
middle ear cartilages & mandibular bones etc.
381Contribution of Facial
Processes to the Adult Face
A – Maxillary Process.
B – Mandibular
Process.
C – Median Nasal
Process
D – Lateral Nasal
Process
Development of Jaws - Mandible
Develops from the cartilage of the Ist
Visceral arch – Meckel’s cartilage.
Forms in membrane.
Provides a frame work around which the
bone of the mandible develops.
Centre of Ossification located – near the
future mental foramen region- starts by 7 th
week I.U.
Ossification of Symphysis completed only at
second year of life.
388
A – Meckel’s cartilage
B – Bone of the
Mandible
C – Tongue
D – Symphysis of
mandible
389 T.S thro Mandible – 8th week I.U
A – Meckel’s cartilage.
B – Dental Lamia.
C – Tongue.
D – Neurovascular
bundle.
390
A – Alveolar process –
with Bud stage of
tooth germ.
B – Neurovascular
bundle.
C – Meckel’s cartilage.
D – Tongue.
Meckel’s Cartilage
A – Alveolar process –
containing the
developing Tooth
germ.
B – Neurovascular
bundle.
C – Tongue.
392 T.S - thro Mandible-Bell stage of Tooth germ
A - Bell stage of
Tooth germ.
B – Alveolar bone –
with Osteoclasts
in Howschip’s
lacunae & seams
of Osteoblasts.
Development of Cartilages - 10th to 14th week I.U
A – Condylar cartilage.
B – Meckel’s cartilage.
C – Developing bone of
Glenoid fossa.
D – Part of developing
Articular Disc.
Postnatal Development & Growth of Mandible
Occurs by Remodelling of bone.
Increase in height - by formation of Alveolar bone
mainly & some by deposition on the Lower
border.
Increase in Length – by deposition on Posterior
surface of Ramus – with compensatory
resorption on Anterior surface & also by
deposition on posterior surface of Coronoid
process & resorption on Ant. Surface of Condyle.
Increase in width – by deposition on outer
surface & resorption on inner surface of
Mandible.
Eventhough Mandible is a single bone
A – At birth.
B – At six years.
C – In Adult.
Development & Growth of Maxilla
Ossifies in membrane.
Centre of Ossification – close to the site of
Decidous Canine.
Spreads into its growing processes:
– Palatine
– Zygomatic
– Frontal
– Alveolar process
387
A – Body of the
Maxilla.
B – Bone extending
into Palate.
C – Nasal cavity.
A – Body of Mandible.
393 B – Ramus of Mandible.
C – Sec. Condylar
Cartilage.
D – Sec. Coronoid
Cartilage.
E – Frontal Bone.
F – Parietal bone.
G – Occipital bone.
H – Squamous part
of Temporal bone.
I - Maxilla
396
R – Registration point
Development of Tongue
A – Lateral Lingual
swellings.
B – Tuberculum
Impar.
C – Copula.
98 Sensory Innervation of Tongue
Ant. 2/3 – by:
Lingual – I arch – Sensation
Chorda Tympani
– II arch - thro Facial
– ( Pre-trematic) Taste
Post. 1/3 by: Glossopharyngeal
– IIIrd arch
A small post. Part near
Epiglottis by: Vagus via
Superior laryngeal – IV arch
Muscles - Hypoglossal
Thyroid gland :
- Develops by invagination of the
endoderm at the junction of the
ectodermal and endodermal parts
of Tongue.
- This invagination forms the
Thyroglossal duct.
- The site of invagination is marked
by a sideral pit called Foramen
Caecum.
Salivary Glands : Derived from the Oral
ectoderm.
Pituitary Gland :
- Bifid tongue.
- Lingual thyroid.
Developmental cysts :