Scribd Logo
Upload

Welcome to Scribd!

  • Utkarsh Singh IM-636

    Uploaded by

    crgmkps6ch
    3 views7 pages
    Hemolytic uremic syndrome (HUS) is a condition that primarily affects young children under 4 years old where small blood vessels become damaged and inflamed, which can lead to clotting throughout the body. It is usually preceded by diarrhea and symptoms include pallor, weakness, and decreased urine output. Diagnosis involves identifying evidence of blood cell destruction, low platelet count, and kidney dysfunction in blood tests along with testing stool samples to detect the bacterial infection or toxins that may be the underlying cause. Treatment focuses on supportive care rather than antibiotics, as antibiotics could worsen symptoms by causing bacteria to release more toxins, and dialysis may be needed in severe cases.

    Original Description:

    Original Title

    Hus

    Copyright

    © © All Rights Reserved

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Hemolytic uremic syndrome (HUS) is a condition that primarily affects young children under 4 years old where small blood vessels become damaged and inflamed, which can lead to clotting throughout the body. It is usually preceded by diarrhea and symptoms include pallor, weakness, and decreased urine output. Diagnosis involves identifying evidence of blood cell destruction, low platelet count, and kidney dysfunction in blood tests along with testing stool samples to detect the bacterial infection or toxins that may be the underlying cause. Treatment focuses on supportive care rather than antibiotics, as antibiotics could worsen symptoms by causing bacteria to release more toxins, and dialysis may be needed in severe cases.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    3 views7 pages

    Utkarsh Singh IM-636

    Uploaded by

    crgmkps6ch
    Hemolytic uremic syndrome (HUS) is a condition that primarily affects young children under 4 years old where small blood vessels become damaged and inflamed, which can lead to clotting throughout the body. It is usually preceded by diarrhea and symptoms include pallor, weakness, and decreased urine output. Diagnosis involves identifying evidence of blood cell destruction, low platelet count, and kidney dysfunction in blood tests along with testing stool samples to detect the bacterial infection or toxins that may be the underlying cause. Treatment focuses on supportive care rather than antibiotics, as antibiotics could worsen symptoms by causing bacteria to release more toxins, and dialysis may be needed in severe cases.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    of 7

    UTKARSH SINGH

    IM-636 UTKARSH Singh

    IM-636
    Introduction
    • Hemolytic uremic syndrome (HUS) is a condition that can occur when
    small blood vessels become damaged and inflamed. This damage can
    cause clots to form in the vessels all through the body.
    Clinical Features

    • Occur in children <4 years old


    • Initial event is Diarrhea
    • After 5-10 days of diarrhea – pallor
    • Weakness
    • Oliguria
    Diagnosis

    • Peripheral smear:- evidence of


    hemolysis : lyses RBCs
    • Low platelets
    • Elevated blood urea & serum creatinine
    • Coombs negative
    • Stool culture :- to isolate the bacteria
    • PCR :- detect bacterial antigen
    • Also, if stool culture is negative,
    demonstrate presence of shiva toxin by
    ELSA
    Treatment

    • His is self limiting condition


    • Treatment is supportive
    • Antibiotics:- no role in management
    • Antibiotics lyse the bacteria- release of
    performed toxins that lead to worsening
    of the disease
    • Dialysis in severe cases
    Thanks

    You might also like