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Research Rationale
Research Rationale
RESEARCH
RATIONALE
THE RESEARCH
RATIONALE IS
YOUR AD FOR
YOUR RESEARCH
02/18/2024 SAMPLE FOOTER TEXT 3
• A well-written background of the
study is like an effective
advertisement for a product or
service.
Unified Coherent/Cohesive
Narrative adheres to the Ideas flows smoothly from
central theme of the study. general context to the main problem.
Compelling
Concise Narrative engages readers to probe
Write-up conveys ideas clearly with deeper and highlights the importance of
fewest words possible. the study.
UNIFIED
RESEARCH OBJECTIVES/
STATEMENT
OF THE PROBLEM.
GLOBAL ISSUES OR PROBLEM
• News report
At the end of 2019, the world was shocked by the emergence of a new
virus that attacks the respiratory system. World Health Organization
has named this virus severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) and named the disease Coronavirus disease-19 (COVID-
19) Globally, as of 8 November 2023, there have been 771,820,937
confirmed cases of COVID-19, including 6,978,175 deaths, reported to
WHO. (WHO, 2020).
Local impact of the PROBLEM
• News report
• Statistics from trusted organization or governement
reports
• Local studies or research that shows the effect of the
problem on the locality of the researcher
Psidium guajava Leaves’ extract sanitizer against corona virus
Disease-19
Discuss why the proposed solution has a potential to solve the said
problem or contribute in solving the said problem
them is the fungi-causing disease called, Candidiasis. In the Philippines, Candidiasis constituted about 80.40% of the total reported serious fungal
infections back in the year 2016 (Batac & Denning, 2017) — that is equal to about 1,490,044 severe fungal infection cases. Unreported cases may be
higher. In the United States, it is the second most common cause of vaginal infection in women (CDC, 2022), 3 out of 4 get affected at some point in their
lifetime, and many experience at least two episodes of the fungal infection (Mayo Clinic, 2023). Cutaneous candidiasis is a type of yeast infection on the
skin mainly caused by the fungus Candida albicans (Medline Plus, 2020). According to an article by Nall (2019), candidiasis of the skin usually isn’t
contagious. However, people with weakened immune systems may develop the condition after touching the skin of an infected person. Those with
compromised immune systems are also more likely to develop a severe infection due to candidiasis. Cutaneous candidiasis causes a red, itchy rash to
form and bumps may appear around the edges (Nall, 2019), this usually appears in the folds of the skin where it is warm and moist (Aaron, 2021). This
type of fungus may not be fatal and can be cured easily unless the host/person has a weakened immune system but treatments are limited due to the
resistance of some species to several antifungals (Zida et. al., 2017). Certain medications are also expensive and they may not even be affordable for
other people; side effects are skin irritation, rashes, and itching on the site of application but this will not be included in the scope of the study. Now, this
problem along with the former prompted the researchers to make an alternative product intended to help people with Cutaneous Candidiasis fungal
infection by making a cure in the chosen form of an antifungal soap and to make low-cost alternative treatment against said fungus, Candida albicans.
•This study will mainly utilize the leaf part of the Karonda (Carissa carandas) plant as the main material. The plant grows in any type of soil and is
drought tolerant which makes it well suited for tropical and subtropical climates (Agrifarming, 2021) like the Philippines. The researchers chose this
specific part of the plant as it exhibited high antifungal activity based on the traditional medicine history of Karonda ( Carissa carandas) and even in recent
literary reviews such as the study conducted by Fartyal & Kumar (2016) and Singh et al. (2020). As this plant is underutilized even for its surprising
medical potential, there are no commercially available products on the market that introduce the plant in the field of medicine—and that is a knowledge
gap this study aims to fill, along with investigating its antifungal activity on said disease Cutaneous Candidiasis, caused by the common fungus Candida
albicans. The study will be using this kind of soap of Karonda (Carissa carandas) leaves as effective in its possible ability to inhibit the growth of
Candidiasis (Candida albicans) fungus that can benefit particularly the field of human health.