PRESENTED BY : GARIMA DUTTA

PRESENTED TO : DR. DEEPTI SINGH

PURINE AND PYRIMIDINE BASES

Purine And Pyrimidine Bases

Purine and Pyrimidine are parent compounds of

two types of nitrogen-containing heterocyclic
aromatic compounds.
PURINE
 Purine is
a heterocyclic aromatic organic
compound that consists of two
rings.
 It is water-soluble.
 Adenine and Guanine
 They are two of the four nucleobases in the nucleic
acid of DNA.
PYRIMIDINE
 Pyrimidine is a simple
aromatic ring.
 The carbon and nitrogen
atoms are connected via
alternating double and
single bonds.
 This bond structure
allows for resonance.
 Cytosine, Thymine, and Uracil.
 Cytosine and Thymine are the two major pyrimidine
bases in DNA.
 In RNA, uracil replaces thymine.
Nucleoside And Nucleotide
Nucleoside is a structure formed by the combination of nitrogen base and
sugar whereas Nucleotides are phosphoric acid esters of nucleosides.
Nucleosides are the structural subunit of nucleic acids such as DNA and
RNA. A nucleoside, composed of a nucleobase, is either a pyrimidine or a
purine, a five carbon sugar which is either ribose or deoxyribose.
Nucleosides play an essential role in intermediary metabolism.

In medicinal field, several nucleosides are used as antiviral or anticancer

agents.
Nucleosides are responsible for encoding, transmitting and expressing
genetic information in all living things.
 Nucleotides are composed of a nitrogenous base, a five-
carbon sugar (ribose or deoxyribose), and at least one
phosphate group.
THANK YOU