Shree Vile Parle Kelavani Mandal’s

INSTITUTE OF PHARMACY, DHULE

Approved by AICTE, PCI, DTE | Affiliated to DBATU Lonere, MSBTE Mumbai

Topic Name - Development & Evaluation of anti-Obesity Polyherbal Formulation

comprising select Indian medicinal plants & Camel Milk Powder.

1. Atharva Rajendra Patkar 6. Jaimin Pravin Gadara

2. Damini Anil Patil 7. Jayesh Kailas Shevatkar
3. Dhanshree Nitin Chavan 8. Lubdha Prashant Badgujar

4. Digvijay Bapurao Patil 9. Ragini Vijay Jadhav

5. Jagruti Narendra Sonawne 10.Swaranjali Vijay Patil

Vision: To Pursue Excellence in Pharmaceutical Education & Research to Develop Competent Professionals 1
 Introduction
Definition of Obesity :- Obesity is a sever as well as chronic disorder which is also an important risk factor for
lifestyle related chronic disease. When an imbalance is caused in the consumption of energy and expenditure of
energy lead to the condition called obesity.
 Obesity is now so common in various geographies that it is beginning to replace conditions arising from
malnutrition and infectious diseases as the most significant contributor to ill health.

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 Bariatric
Surgery

Yoga & Need of Pharmaco

Gym
study Therapy

Aleuron
Capsule

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 Materials and Methods

Sr Name of the Ingredients Quantity Taken

No.
1 Carrom Seeds 5 gm
2 Fenugreek 5 gm
3 Cinnamon 5gm
4 JackFruit 5 gm
5 Cumin 5 gm
6 Flex Seeds 10 gm
7 Camel Milk 5 gm
8 DrumStick Powder 10 gm
9 Ash Gourd Powder 10 gm
10 Mentha Q.S.
11 Fennel Q.S.
12 Stevia Q.S.
13 Cardamom Q.S. Ingredients

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 Methods and Procedure

Phytochemical
Screening Test
Physicochemical Formulation of
Flow Properties
Investigation Tablet
a)Alkaloid a) Ash Value a)Angle of a)Hardness
b)Flavonoids b)Extractive Repose b)Thickness
c)Amino Acids Value b)Bulk Density c)Diameter
d)Carbohydrate c)Loss On c)Tapped
e)Protein Drying Density
d)Hausner
f) Steroids Ratio
g) Fats and Oil
h)Glycoside

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 Results

 Various tests were performed and results are shown in the following table-
Sr Name of the Primary And Name of the Test Inference
No. Secondary Metabolite
1 Alkaloid Mayer Test Negative
Wagners Test
Dragendorff Test
Hagers Test

2 Flavanoid Shinoda Test Negative

3 Glycoside Legal Test Positive
Baljet Test

4 Carbohydrate Fehling Test Positive

Benedict Test

5 Protein Millon’s Test Positive

6 Amino Acid Ninhydrine Test Negative
7 Steroid Salkowski Test Positive
8 Fats And Oils Solubility Test Saponin Negative
Test

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 Results

Angle Bulk Tapped Hausner LOD Ash Value Extractive Value

of Density Density Ratio Alcohol Soluble Water
Repose Soluble
Total Ash Acid Water
Insoluble Soluble

Θ= 0.41 0.625 1.524 0.38 89.5 5 80.5 7.42 6.25

tan-1= gm/ml gm/ml
30.98

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 Conlusion

 Current study has been performed to develop and evaluate a polyherbal formulation to
manage obesity, as an alternative solution on allopathic/ synthetic drug and surgery.
 A herbal formulation in the form of a tablet was developed and evaluated using various
parameters as part of preliminary investigation.
 This is the first formulation in this category comprising jackfruit, ash gourd, camel milk, and
other putative Indian medicinal plants.
 Further optimization is underway to make formulation easy to handle and use in a palatable
and user-friendly manner.

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 Future Scope

Further optimization is underway to make formulation easy to handle and use in a palatable and
user-friendly manner.

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 REFERENCES
1.Mopuri R, Islam MS (2017) Medicinal plants and phytochemicals with anti-obesogenic potentials: a review. BioMed
pharma other 89:1442-1452. http://doi.org/10.1016/j.biopha.2017.02.108
2 Prakash Raj Pandeya, Gopal Lamichhane, Ramakanta Lamichhane Antiobesity Activity of Two Polyherbal
Formulation in High Fat Diet -Induced Obese C57BL/6J.Hindawi BioMed Research International Volume 2022.http://
doi.10.1155/2022/9120259.
3.C.K. KOKATE, Practical Pharmacognosy fifth edition, Vallabh prakashan, pp.
4. Dr.K.R. Khandelwal, Dr. Vrunda K. Sethi Practical Pharmacognosy, Nirali Prakashan, pp.
5.Acharya Balkrishna, Anawica Singh, Jaydeep Singh Antiobesity activity of PHF Divya- Medohar-Vati by inhibition of
pancreatic lipase activity & Triglyceride translocation through enterocyte ELSEVIER (2022)1

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Vision: To Pursue Excellence in Pharmaceutical Education & Research to Develop Competent Professionals 11