INTRODUCTION TO HEALTH AND SCIENCE

Supervised by ACETONE
Dr. Alan Ahmed
 OUTLINE

• MSDS of acetone
• Hazards identification
• Stability and reactivity
• Physical and chemical properties
• Toxicological profile
 HAZARDS IDENTIFICATION

• Classification of the substance or mixture:(According to Hazard Class:

Regulation EC 1272/2008 classified as Flammable Liquid
Category 2, Eye Irritant Category 2, Specific Target Organ
Toxicity Single Exposure Category 3. ).
• Label element: (GHS Pictogram).
• Flammable Liquids, Category 2
• Eye Irritation, Category 2
• Specific Target Organ Toxicity-Single Exposure, Category 3
Hazard Statements:
• H225: Highly flammable liquid and vapor
• H319: Causes serious eye irritation
• H336: May cause drowsiness or dizziness
Supplemental Hazard Information (EU):
• EUH066: Repeated exposure may cause skin dryness or cracking
Signal Word: Danger

Precautionary statements:
• P210: Keep away from heat/sparks/open flames/hot surfaces – No
smoking.
• P305+351+338: IF IN EYES: Rinse cautiously with water for
several minutes. Remove contact lenses if present and easy to do –
continue rinsing.
• P337+313: Get medical advice/attention.
• P403: Store in a well ventilated place.
 STABILITY AND REACTIVITY

• Reactivity: Reacts vigorously with oxidizing agents.

• Chemical stability: Stable under normal ambient temperature conditions.
• Possibility of hazardous reactions: Hazardous polymerization will not occur.
• Conditions to avoid: Avoid heat, flames and other sources of ignition.
• Incompatible materials: Strong oxidizing substances. Strong acids.
• Hazardous decomposition products: Not known
 PHYSICAL AND CHEMICAL
PROPERTIES

Information on basic physical and chemical properties:

Appearance – A clear, colorless liquid Boiling point – 56°C

Odor – Acetone, Ketone
pH – 7
Melting Point/freezing point – (-95°C)
Flammability limit % (Upper) – 13.30
Flammability limit % (lower) – 2.15
Relative density – 0.79 @20 °C
Partition coefficient – not available
Decomposition temperature – not available
Explosive properties – not available
Flash point – -18°C (closed cup)
Evaporation rate – 7.70
Flammability – highly flammable
Vapour pressure – 24.7 kPa
Vapour density (air=1) – 2
Solubility – soluble in water
Auto ignition temperature – not available
Viscosity – not available
Oxidizing properties – not available
 TOXICOLOGICAL PROFILE

• Information on toxicological effects:

• The product is non toxic to aquatic organisms. LC50> 5500 mg/l 96h (fish), EC50 > 10022 mg/l (daphnia).
• Acute toxicity – LD50 (oral rat) 9570mg/kg.
• Ingestion may cause severe internal injury and stomach pain or vomiting.
• Skin corrosion/irritation – prolonged or repeated skin contact with the product may cause removal of natural fats from the skin, resulting in non allergic
contact dermatitis and absorption through skin.
• Serious eye damage/irritation – Irritation to eyes and may cause redness and pain.
• Respiratory or skin sensitization – not known.
• Germ cell mutagenicity – No component of this product at levels greater than 0.1% is classified by established regulatory criteria as a mutagen.
• Carcinogenicity – No component of this product at levels greater than 0.1% is identified as a carcinogen by AGGIH, the International Agency for Research
of Cancer (IARC) or the European Commission (EC). Classified A4 by ACGIH (Acetone).
• Reproductive toxicity – No component of this product at levels greater than 0.1% is classified by established regulatory criteria as a reproductive toxin.
• STOT- single exposure –vapours may cause drowsiness or dizziness. Vapours may irritate respiratory system or lungs, CNS depressant. Symptoms and signs
include headache, dizziness, fatigue, muscular weakness and in extreme cases loss of consciousness.
• STOT-repeated exposure – not known.
• Aspiration hazard – not known.