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Structural Infectious and Inflammatory Cardiac Disorders and Medical Management
Structural Infectious and Inflammatory Cardiac Disorders and Medical Management
Structural Infectious and Inflammatory Cardiac Disorders and Medical Management
PREPARED BY:
ANTHONY C. BARRERA, RN
VALVULAR DISORDERS
• Involves valves of the heart (tricuspid, mitral, pulmonic, and
aortic valves)
• Examples are:
Mitral Valve Prolapse
Mitral Regurgitation
Mitral Stenosis
Aortic Regurgitation
Aortic Stenosis
MITRAL VALVE PROLAPSE
• Usually produces no symptoms.
• Rarely, it progresses and can result in sudden death
• No clear cause, but associated with inherited connective tissue
disorders
• One or both mitral valve leaflets balloons back into the atrium
during systole
• Can result in mitral regurgitation
CLINICAL MANIFESTATIONS
• Most people may never have symptoms
• Small number of patients will have fatigue, shortness of breath,
lightheadedness, dizziness, syncope, palpitations, chest pain, or
anxiety
ASSESSMENT AND DIAGNOSTIC FINDINGS
• Extra heart sound (a mitral click)
• A murmur of mitral regurgitation may be heard
• Diagnostic procedure is echocardiography
MEDICAL MANAGEMENT
• Symptomatic management only
• Most patients do not require medication, but some are
prescribed antiarrhythmic medications
• For severe, mitral valve repair or replacement may be required
MITRAL REGURGITATION
• Blood flows from the left ventricle back into the left atrium
during systole.
• Edges of mitral valve leaflets do not close completely during
systole.
• May be chronic or, less commonly, acute
• Common causes are degenerative changes of the mitral valve,
ischemia of the left ventricle, rheumatic heart disease
CLINICAL MANIFESTATIONS
• Chronic mitral regurgitation is often asymptomatic
• Acute mitral regurgitation manifests as severe and sudden
congestive heart failure
• Common symptoms: dyspnea, fatigue, and weakness
ASSESSMENT AND DIAGNOSTIC FINDINGS
• Systolic murmur
• Pulse may be regular or irregular
• Diagnostic procedure is echocardiography
MEDICAL MANAGEMENT
• Angiotensin-converting enzyme (ACE) inhibitors
• Angiotensin receptor blockers (ARBs)
• Beta-blockers
• Surgical intervention: mitral valvuloplasty, valve replacement,
MitraClip (for degenerative form of regurgitation)
MITRAL STENOSIS
• Reduced blood flow from the left atrium into the left ventricle
due to narrowed mitral valve orifice
• Usually caused by rheumatic endocarditis
CLINICAL MANIFESTATIONS
• First symptom: dyspnea on exertion (DOE)
• progressive fatigue
• decreased exercise tolerance
• dry cough or wheezing
• For severe: hemoptysis, palpitations, orthopnea, paroxysmal
nocturnal dyspnea, atrial arrhythmias
ASSESSMENT AND DIAGNOSTIC FINDINGS
• Low-pitched, rumbling diastolic murmur
• Weak and irregular pulse
• Echocardiography used to diagnose and quantify the severity
MEDICAL MANAGEMENT
• Anticoagulant medications
• If atrial fibrillation develops, cardioversion may be attempted
• Surgical intervention: valvuloplasty, commissurotomy,
percutaneous transluminal valvuloplasty
AORTIC REGURGITATION
• Also called aortic insufficiency
• Backward flow of blood into the left ventricle from the aorta
during diastole
• Causes: congenital valve abnormality, inflammatory lesions at
the aortic valve leaflets, rheumatic endocarditis, blunt chest
trauma
CLINICAL MANIFESTATIONS
• Pounding or forceful 2121 heartbeat, especially in the head or
neck
• visible or palpable arterial pulsations at the carotid or temporal
arteries
• Dyspnea on exertion (DOE), SOB
• Fatigue, orthopnea
ASSESSMENT AND DIAGNOSTIC FINDINGS
• High-pitched, blowing diastolic murmur is heard at the third or
fourth intercostal space at the left sternal border
• Water hammer (Corrigan’s) pulse
• Diagnostic procedure: echocardiography, cardiac magnetic
resonance imaging (MRI), cardiac catheterization
MEDICAL MANAGEMENT
• If atrial fibrillation develops, cardioversion may be attempted
• ACE inhibitors
• Dihydropyridine calcium channel blockers
• Surgical intervention: aortic valve replacement or valvuloplasty
AORTIC STENOSIS
• Narrowing of the orifice between the left ventricle and aorta
• Caused by degenerative calcification, congenital leaflet
malformations, Rheumatic endocarditis
CLINICAL MANIFESTATIONS
• Often asymptomatic
• first symptom to appear is dyspnea on exertion (DOE)
• Other symptoms: orthopnea, pulmonary edema, paroxysmal
nocturnal dyspnea (PND), syncope, angina pectoris,
• low pulse pressure (30 mm Hg or less)
ASSESSMENT AND DIAGNOSTIC FINDINGS
• Loud, harsh systolic murmur is heard over the aortic area and
may radiate to the carotid arteries and apex of the left ventricle
• S4 sound may be heard
• Palpable vibration
• Diagnostic procedure: echocardiography, cardiac MRI, or
computed tomography (CT) scanning, left-sided heart
catheterization, graded exercise studies (stress tests)
MEDICAL MANAGEMENT
• Anti-arrhythmia medications
• Transcatheter aortic valve replacement (TAVR)
• Balloon percutaneous valvuloplasty
NURSING MANAGEMENT
• Instruct patient to report new symptoms or changes in
symptoms
• educate the patient about how to minimize the risk of
developing infective endocarditis
• advised to avoid strenuous activities, physical exertion,
competitive sports, and pregnancy
• restrict sodium intake
NURSING MANAGEMENT
• Monitor vital signs and note ant changes
• Assess patient for signs and symptoms of heart failure: fatigue,
DOE, decreased activity tolerance, coughing, hemoptysis
• Monitor for any arrhythmias
• Collaborate with the patient to develop a medication schedule
• Educate the patient about the diagnosis, progressive nature of
the disease including the infectious pathogen, and treatment
plan
SURGICAL MANAGEMENT
• Valvuloplasty = repair of cardiac valve
• Types of valvuloplasty:
1. Commissurotomy
2. Annuloplasty
• Transesophageal Echocardiogram (TEE)
COMMISSUROTOMY
Types of commissurotomy:
1. Closed Commissurotomy/Balloon Valvuloplasty
Most often used for mitral and aortic stenosis
Non-surgical or percutaneous technique
Contraindicated for patients with left atrial or ventricular
thrombus, severe aortic root dilatation, significant mitral valve
regurgitation, and severe valvular calcification
Performed in a cardiac catheterization laboratory
Mitral Balloon Valvuloplasty
• The Inoue-Balloon inflates in three
stages:
1st below the valve,
2nd above the valve
3rd in the valve orifice
Types of commissurotomy:
II. Open Commissurotomy
Involves open heart surgery
Less commonly used
Advantage: removal of thrombus or calcification, if present
SURGICAL MANAGEMENT CONT…
ANNULOPLASTY
Refers to repair of the valve annulus, resulting to narrowing of
the valve orifice
Used for valvular regurgitation.
Involves 2 techniques:
1. With the use of annuloplasty ring
2. Tightening the annulus
Annuloplasty Ring Insertion
LEAFLET REPAIR
Achieved by removing the extra tissue
Elongated tissue may be tucked or sutured, a technique called
plication, with the use of pericardial or synthetic patch
SURGICAL MANAGEMENT CONT…
CHORDOPLASTY
Repair of the chordae tendineae
SURGICAL MANAGEMENT CONT…
VALVE REPLACEMENT
Preferred procedure for patient with less chance of success
with repair
Indicated for valves with extensive calcification, severely
fibrotic or fused leaflets, chordae tendineae, or papillary
muscles
Involves open heart surgery
Cardiopulmonary bypass or sternotomy is needed
VALVE REPLACEMENT
MECHANICAL AND TISSUE VALVES
MECHANICAL VALVES
• Examples are bileaflet, tilting disc, caged ball
• More durable than tissue prosthetic valves
• Often used for younger patients
TISSUE VALVES
• Has three (3) types:
1. Bioprosthesis = made from animal tissue (heterography) and used
for aortic, mitral, and tricuspid valve replacement
2. Homografts (allografts) = obtained from cadaver tissue donations
(human valves) and used for aortic and pulmonic valve
replacement
3. Autografts (autologous valves) = obtained from patients own
pulmonic valve and a portion of pulmonary artery for use as the
aortic valve
NURSING MANAGEMENT FOR SURGICAL PATIENT
• Assesses for signs and symptoms of heart failure and emboli
• Auscultate the chest for changes in heart sounds at least every 4
hours
• Vital signs are assessed every 5 to 15 minutes and as needed
until the patient recovers from anesthesia or sedation, and then
are assessed according to unit protocol.
• Intravenous (IV) medications may be used to increase or
decrease blood pressure, to treat arrhythmias, to increase or
decrease heart rate
NURSING MANAGEMENT FOR SURGICAL PATIENT
• Health teaching about wound care and patient education
regarding diet, activity, medications, and self-care
• Educate the patient about anticoagulant therapy, explaining the
need for frequent follow-up appointments and blood laboratory
studies.
• Provide education about all prescribed medications, including
the name of medication, dosage, actions, prescribed schedule,
potential adverse effects, and any drug-drug or drug-food
interactions
NURSING MANAGEMENT FOR SURGICAL PATIENT
• Educate patient about how to minimize the risk of developing
infective endocarditis
• Inform patient that an echocardiogram may be performed 3 to 4
weeks after hospital discharge
CARDIOMYOPATHY
• Disease of the heart muscle that is associated with cardiac
dysfunction
• Classified according to the structural and functional
abnormalities of the heart muscle
• Ischemic cardiomyopathy = used to describe an enlarged heart
caused by coronary artery disease, which is usually
accompanied by heart failure
Two Major Groups of Cardiomyopathy
1. Primary Cardiomyopathy
Focused primarily on the heart muscle
2. Secondary Cardiomyopathy
Myocardial involvement secondary to the influence of a
vast list of disease processes
Examples of Cardiomyopathy
1. Dilated Cardiomyopathy
Most common
Distinguished by significant dilation of the ventricles
without simultaneous hypertrophy and systolic dysfunction
2. Hypertrophic Cardiomyopathy
An autosomal dominant genetic disorder that leads to
increased heart muscle size and mass
Leading cause of sudden death in adolescents and young
adults, particularly in athletes
Examples of Cardiomyopathy
3. Restrictive Cardiomyopathy
Least common
Characterized by diastolic dysfunction caused by rigid ventricular
walls that impair diastolic filling and ventricular stretch
Can be inherited or acquired disease
4. Unclassified Cardiomyopathy
Different from or have characteristics of more than one of the
previously described types and are caused by fibroelastosis,
noncompacted myocardium, systolic dysfunction with minimal
dilation, and mitochondrial diseases
HEART TRANSPLANT
Therapeutic option for patients with end-stage heart disease
Orthotopic transplantation = the most common surgical
procedure for cardiac transplantation
Bicaval technique = removal of the recipient’s heart, and the
implantation of the donor heart with intact atria at the vena cava
and pulmonary veins
Orthotopic Method of Heart Transplantation
INFECTIOUS DISEASE OF THE HEART
Heart’s layers may be affected by an infectious process
Infections are named for the layer of the heart most involved in
the infectious process: infective endocarditis (endocardium),
myocarditis (myocardium), and pericarditis (pericardium)
Ideal management for all infectious diseases is prevention.
IV antibiotics usually are necessary once an infection has
developed in the heart.
INFECTIOUS DISEASE OF THE HEART
Infective Endocarditis
Microbial infection of the endothelial surface usually by Staphylococci or
Streptococci
Rare, but it has a high mortality rate
Onset is insidious
Risk factors: implanted cardiac devices, congenital heart disease, cardiac
transplant
Primary presenting symptoms are fever and a heart murmur.
Heart failure is the most frequent complication
INFECTIOUS DISEASE OF THE HEART
Pericarditis
Inflammation of the pericardium
Etiology can be infectious (viral, bacterial, fungal, parasitic) or
noninfectious (autoimmune disorders)
INFECTIOUS DISEASE OF THE HEART
Pericarditis cont…
Inflammatory process may lead to an accumulation of fluid in
the pericardial sac (pericardial effusion) and increased pressure
on the heart, leading to cardiac tamponade
The most characteristic symptom of pericarditis is chest pain
Clinical manifestation of is a creaky or scratchy friction rub
heard
INFECTIOUS DISEASE OF THE HEART
Sample Nursing Dx
Acute pain associated with inflammation of the pericardium
Lack of knowledge of diagnosis and therapeutic self-care
management
INFECTIOUS DISEASE OF THE HEART
Nursing Intervention
Provide rest periods
Position patient in sitting upright and leaning forward, chair
rest may be more comfortable
Gradually resume patient’s ADL
Educate the patient about the causes
Monitor potential of complications
HEART FAILURE
Structural or functional cardiac disorders that make heart is
unable to pump enough blood
Impaired contraction of the heart (systolic dysfunction) or
filling of the heart (diastolic dysfunction)
Chronic, progressive condition that is managed with lifestyle
changes and medications
Morbid consequence of another disease or disorder. Primary
cause is atherosclerosis of the coronary arteries
Goal: prevention of decompensated heart failure episodes
Heart Failure cont….
Most common type of HF is systolic HF
Goal: prevention of decompensated heart failure episodes
PATHOPHYSIOLOGY
Clinical Manifestation
The cardinal manifestations are dyspnea, fatigue, fluid retention
S/S are related to the affected ventricle:
1. Right-sided heart failure
• Dependent edema, hepatomegaly, ascites, and weight gain
2. Left-sided heart failure
• Pulmonary interstitial edema
• Dyspnea, cough, pulmonary crackles, low oxygen saturation
levels, and extra heart sound may be heard
Clinical Manifestation cont…
Two main types left-sided heart failure, with a third emerging
category:
1. Heart failure with reduced ejection fraction (HFrEF)
also known as systolic heart failure
2. Heart failure with preserved ejection fraction (HFpEF)
also known as diastolic heart failure
3. Heart failure with midrange ejection fraction (HFmrEF)
Emerging classification category
Congestive Heart Failure
Failure of dual mechanisms, in which right-sided heart failure
occurs as a result of left-sided failure
When the left ventricle fails, fluid pressure is transferred back
through the lungs, damaging the right side of the heart. The
right side of the heart loses its pumping power, the blood backs
up in the body’s venous system causing swelling or congestion
in the legs, ankles, and swelling within the abdomen
Pulmonary Edema
Breakdown of physiologic compensatory mechanisms
Sometimes referred to as acute decompensated heart failure
Occur following acute MI or as an exacerbation of chronic HF
When the left ventricle cannot handle the volume overload, and blood
volume and pressure build up in the left atrium. The rapid increase in
atrial pressure results in an acute increase in pulmonary venous pressure,
which produces an increase in hydrostatic pressure that forces fluid out
of the pulmonary capillaries and into the interstitial spaces and alveoli
Clinical Manifestation of Pulmonary Edema
Onset of breathlessness Sense of suffocation
Restless Tachypnea and tachycardia
Tachypnea and tachycardia Skin is pale to cyanotic
Hands may be cool and clammy Jugular Vein Distention
Incessant coughing Foamy sputum
Anxious and confused Crackles
HEART FAILURE
Sample Nursing Dx
Ineffective tissue perfusion related to pulmonary congestion
Activity intolerance related to low level of oxygen in the blood
Hypervolemia related to breakdown of physiologic
compensatory mechanisms
• Anxiety related to disease progressive condition
HEART FAILURE
Nursing Intervention
Provide rest periods
Position patient in sitting upright and leaning forward, chair
rest may be more comfortable
Gradually resume patient’s ADL
Limit physical activities to only 3–5 min at a time, one to four
times per day
HEART FAILURE
Nursing Intervention
Educate the patient regarding fluid and diet restrictions (low
sodium)
Assess the patient’s anxiety level
Oxygen therapy may be necessary
Continuous positive airway pressure (CPAP) might be
recommended
Monitor potential of complications
HEART FAILURE