THE MIRACLE PLANT :KALANCHOE PINNATA AND ITS USES

PRESENTED BY: PROJECT GUIDE :

DYANESHWAR.K.GAVHANE MS.SHRADDHA LASGARE MAM
B-PHARM (4TH YR.) ( ASSISTANT PROF.)

LATE. TILOKACHAND KUCHE SUKSHAN PRASARAK MANDAL’S

RAOSAHEB PATIL DANVE COLLEGE OF PHARMACY
BADNAPUR
 Index:

SR NO CONTENT PAGE NO
1 Introduction 08-10
2 Litrature Review 12

3 Description 12-16

4 Aim & Objectives 15

5 Plan of Work 16

6 Material & Methods 17-19

8 Result and Discussion 20

9 Conclusion 20
10 Refferance 21-22
11 Experimental Work 23
 Introduction:

 Kalanchoe is a medicinal plant largely used in folk medicine for the treatment of kidney stones, gastric ulcer,
pulmonary infection, rheumatoid arthritis etc. Kalanchoe pinnata has become naturalized in temperate regions of Asia,
Australia, New Zealand, West Indies, Macaronesia, Mascarenes, Galapagos, Melanesia, Polynesia, and Hawaii. In
many of these, such as Hawaii, it is regarded as an invasive species. In French Polynesia, Kalanchoe pinnata has been
declared a threat to biodiversity.

 Geographical Charactors :

 This plant is mostly found on plains, tropical and temperate regions of Africa,
 Australia and America.

Fig.no.1 kalanchoe Pinnata

 Literature Survey :

1. Kirtikar K.R. & Basu B.D., Indian Medicinal Plants with illustrations. Volume-5, second edition, Oriental enterprises. 2003: 1394-1396.:
Shade dried leaves were successively extracted and determined phenolic and flavonol content of the extracts. Six different in vitro antioxidant assays
such as 1, 1’-diphenyl-2-picrylhydrazyl (DPPH), lipid peroxidation (LPO), nitric oxide, hydrogen peroxide radical scavenging, reducing power of
the extracts and total antioxidant capacity.

 2. The Wealth of India A Dictionary of Indian Raw Materials and Industrial products, (Volume-5 )(H-K) First Supplement Series,
National Institute of Science Communication and Information Resources, Council of Scientific and Industrial Research, New Delhi;1997:
31. In the case of minerals, the occurrences have been listed with fuller details while the informations regarding their reserves arc lacking. Chemical
compositionannual productions and imports are also mentionedThe treatise on animals and animal products JS exhaustive and quite informative

 3. Nandkarni A.K., Indian Materia Medica, Volume-1, Third edition, Popular Prakashan, Bombay, 2005:1402 & 221. m Ir«7 "'“*• of S tclusa
is held tn mucilage and are "’oof of rheumatism- Stems abound both for external an/'"^ d. flavonoid content of the extracts. Six different in vitro
antioxidant assays such as 1, 1’-diphenyl-2-picrylhydrazyl (DPPH), lipid peroxidation (LPO), nitric oxide, hydrogen peroxide radical scavenging.
4. Samim Sofika Begum and Rajib Jogoi, Herbal recipe prepared during Bohag or Rongali Bihu in Assam, Indian Journal of
Traditional Knowledge, 2007;6(3): 417-422. 4. Samim Sofika Begum and Rajib Jogoi, Herbal recipe prepared during Bohag or Rongali
Bihu in Assam, Indian Journal of Traditional Knowledge, 2007;6(3): 417-422.

5. S Huissain and DK Hore, Collectiopn and conservation of major medicinal plants of Darjeeling and Sikkim, Indian Journal of
Traditional Knowledge, 2007;6(2): 352-357.The major constrints in this sector is poor marketing facilities for raw materials as a
result :the farmers are hesitsnt to make up large scale cultivation,
 Plant Profile:
Kalanchoe Pinnata

Taxonomy:

Kingdom : Plantae (Plants)

Subkingdom : Tracheobionta (Vascular plants)

Super division : Spermatophyta (Seed plants)

Division : Magnoliophyta (Flowering plant)

Class : Magnoliopsida (Dicotyledonous)

 Aim and objective

Aim: The Miracle Plant :Kalanchoe pinnata and its benefits .

Objectives:

1.It treats the Gastric ulcer.

2.To Treat Respiratory infections.

3.For removal of Kidney Stone crystals.

4.In Boils

5.Shows wound healing activity.

 Pharmacological Activities :

Pharmacological Activities :

The parts of the plant are supposed to be closely connected with characteristics of ‘astrality’ corresponding to the soul
organisation in humans, controlling the hysteria (excess of activity) of the metabolic-limb system.

1.Wound-healing activity:

The ethanolic extract of K. pinnata showed significant wound-healing activity by decreasing the size of the affected area
as well as oedema at the wounded site.

2.Antioxidant activity :

Antioxidative agents protect cells against the damaging effects of reactive oxygen species, such as singlet oxygen,
superoxide, peroxyl radicals, hydroxyl radicals and peroxynitrite.
3.Antitumour activity :

Devbhuti et al., (2012) experimented on mice by inducing tumour formation in the peritoneal region of the body.
Methanolic and aqueous extracts of the plant were administered as drugs in specific dosages.

4.Antiviral activity :

Human papillomavirus (HPV) is one of the sexually transmitted viruses, acting as a major threat to humans. Cervical
cancer which is on the rise is caused by HPV.

5.Antimicrobial activity:

Okwu and Nnamdi (2011a, b) isolated two flavonoids and an alkaloid from the ethanolic leaf extract of K. pinnata and
proved the antimicrobial activity of the plant.
6.Antileishmanial activity :

The protozoans of the genus Leishmania cause the disease Leishmaniasis. The aqueous extract of K. pinnata was given
orally to mice infected with Leishmania amazonensis.

7.Anthelmentic activity :

Majaz et al., (2011b) did a comparative study on the activity of different solvents against the commonly found earthworms
and roundworms. The results of their study revealed that chloroform, methanolic and aqueous extract of roots of K. pinnata
possess anthelmentic activity.

8.Anti-diabetic activity:

The presence of zinc in plants could mean that plants can play valuable roles in management of diabetes which
result from insulin malfunction.
 Method of Preparation

1.Take 12-13 kalanchoe leaves .

2.Wash it Properly with water.

3.After that add it into the blender.

4.Blend it properly add some jaggery with it.

Fig.no.2 kalanchoe juice
 Physiochemical tests:

Sr.no Test Observation

1. Physical Test: Semi solid

1) Nature Green

2) Colour Pleasant

3) Odour Sweet to sour.

4)Taste
2. pH 7.2

3. Abrasiveness’ There were 2

scratches present

4. Foaming Ability 56% foam observed

 Result:

A consolidated review on the pharmacological uses of the medicinal plant k.pinnata (linn).Which
included a broad spectrum of activities like wound healing ,antimicrobial ,antiviral ,antioxidant ,
anticancer, antihypertensive,anti-inflammatory.etc.

CONCLUSION :

Kalanchoe pinnata is typically found in tropical and temperate regions of the world. It is
commonly known to exhibit a wide range of potential pharmacological activities which involves the
treatment of various serious disorders mainly related to mankind. Kalanchoe pinnata is widely used
as heavenly herb.
 Referances:

1. Kirtikar K.R. & Basu B.D., Indian Medicinal Plants with illustrations. Volume-5, second edition, Oriental
enterprises. 2003: 1394-1396.

2. The Wealth of India A Dictionary of Indian Raw Materials and Industrial products, (Volume-5 )(H-K) First
Supplement Series, National Institute of Science Communication and Information Resources, Council of Scientific
and Industrial Research, New Delhi;1997: 31.

3. plants.usda.gov

4. www.raintree. com

5. Nandkarni A.K., Indian Materia Medica, Volume-1, Third edition, Popular Prakashan, Bombay, 2005:1402 & 221.
6. Samim Sofika Begum and Rajib Jogoi, Herbal recipe prepared during Bohag or Rongali Bihu in Assam, Indian
Journal of Traditional Knowledge, 2007;6(3): 417-422.

7. S Huissain and DK Hore, Collectiopn and conservation of major medicinal plants of Darjeeling and Sikkim, Indian
Journal of Traditional Knowledge, 2007;6(2): 352-357.

8. Prabal Sen, Mihin Dollo, Manabendra Dutta Chaudhury , Dhrupad Choudhury, Documentation and Traditional
Herbal Knowledge of Khamptis of Arunachal Pardesh, 2008;7(3): 438-442.

9.W. Bates. (2014). The biology of African savannahs. Oxford University Press, USA: pp.

10. S.V. Pattewar. (2012). Kalanchoe pinnata: Phytochemical and pharmacological profile. International Journal of
Pharmaceutical Sciences and Research. 3(4): 993.
11. M.L. Willcox, B. Gilbert. (2009). Traditional medicinal plants for the treatment and prevention of human parasitic
diseases.

12.E.S. Teoh. (2016). Medicinal orchids of Asia. Springer: pp.

13.S.M. Khasim, C. Long, K. Thammasiri, H. Lutken, Medicinal Plants: Biodiversity, Sustainable Utilization and
Conservation. In Springer.

14. N. Menon, J. Sparks, F.O. Omoruyi. (2016). Oxidative stress parameters and erythrocyte membrane adenosine
triphosphatase activities in streptozotocin-induced diabetic rats administered aqueous preparation of Kalanchoe
Pinnata leaves. Pharmacognosy research. 8(2): 85.
 Experimental Work:

Fig.no.3.juice of kalanchoe pinnata

Fig,no.1 kalanchoe plant Fig.no.2.Extraction of juice

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