Dr. Gulzar Saeed MBBS FCPS Professor & Head Department of Orthopedic Surgery FRPMC Karachi PERTHES DISEASE Legg-Calve-Perthes Disease is an idiopathic avascular necrosis of the proximal femoral epiphysis in children. PERTHES DISEASE
• Affects 1 in 10,000 children
• 4-8 years is most common age of presentation • Male to female ratio is 5:1 • Higher incidence in urban areas and among lower socioeconomic class • Bilateral in 12% PERTHES DISEASE RISK FACTORS
• Disruption of blood supply to femoral head- osteonecrosis-
revascularization with subsequent resorption and later collapse- creeping substitution - remodelling after collapse • Controversial aetiology • Thrombophilia has been reported to be present in 50% of patients • Up to 75% of affected patients have some form of coagulopathy • Repeated subclinical trauma and mechanical overload lead to bone collapse and repair (multiple-infarction theory) • Maternal / passive smoking CATTERALL CLASSIFICATION
Based on degree of head involvement
• Group I- Involvement of the anterior epiphysis only • Group II- Involvement of the anterior epiphysis with a central sequestrum • Group III-Only a small part of the epiphysis is not involved • Group IV-Total head involvement CATTERALL CLASSIFICATION • Group I- Involvement of the anterior epiphysis only • Group II- Involvement of the anterior epiphysis with a central sequestrum • Group III-Only a small part of the epiphysis is not involved • Group IV-Total head involvement PRESENTATION
• Symptoms: insidious onset- may cause painless limp-
intermittent hip, knee, groin or thigh pain • Physical exam- hip stiffness- loss of internal rotation and abduction-gait disturbance-antalgic limp-Trendelenburg gait (head collapse leads to decreased tension of abductors)-limb length discrepancy. IMAGING
• Radiographs: AP of pelvis and frog leg laterals-medial joint space
widening (earliest) from less ossification of head-irregularity of femoral head ossification-decreased size of ossification center • sclerotic appearance-cresent sign (represents a subchondral fracture) • Bone scan: can confirm suspected case of LCPD-decreased uptake (cold lesion) can predate changes on radiographs ;provides information on extent of femoral head involvement • MRI : early diagnosis revealing alterations in the capital femoral epiphysis and physis ;more sensitive than radiograph PERTHES DISEASE- IMAGING PERTHES DISEASE- IMAGING TREATMENT • TREATMENT GOALS • Resolution of symptoms: NSAIDs, traction, crutches, restoration of range of motion • Physic al therapy , • containment of hip • Improve range of motion, bracing, proximal femoral osteotomy, pelvic osteotomy • Ensure that femoral head is well seated in acetabulum TREATMENT • Nonoperative: observation alone, activity restriction (non-weightbearing), and physical therapy (ROM exercises) • Indications: children < 8 years of age • Operative: femoral and/or pelvic osteotomy • indications: children > 8 years of age, • technique: proximal femoral varus osteotomy to provide containment • pelvic osteotomy: Salter or triple innominate osteotomy • Shelf arthroplasty may be performed to prevent lateral subluxation and resultant lateral epiphyseal overgrowth SLIPPED CAPITAL FEMORAL EPIPHYSES
A condition of the proximal femoral physis that
leads to slippage of the metaphysis relative to the epiphysis, and is most commonly seen in adolescent obese males SLIPPED CAPITAL FEMORAL EPIPHYSES • Occurs due to axial and rotational mechanical forces which act on a susceptible physis • Metaphysis translates anterior and externally rotates epiphysis remains in the acetabulum and lies posterior/inferior to the translated metaphysis • Increased risk in adolescence because: the perichondrial ring thins and weakens, physis is still vertical in this age group (160° at birth to 125° at skeletal maturity), which results in increased shearing forces SLIPPED CAPITAL FEMORAL EPIPHYSES • Associated conditions: endocrine disorders • Hypothyroidism. labs: elevated TSH • renal osteodystrophy. labs: elevated BUN and creatinine • growth hormone deficiency • panhypopituitarism • endocrine workup indicated if child is < 10 years old SLIPPED CAPITAL FEMORAL EPIPHYSES: PRESENTATION • History: most commonly atraumatic, although some present after an injury. pain has often been present for several months • Symptoms: pain in hip (52%), groin (14%) and thigh (35%) • knee pain: 15-50% present with knee pai • physical exam – inspection-abnormal gait / limp-antalgic, waddling, externally rotated gait or Trendelenburg gait-abnormal leg alignment • loss of hip internal rotation, abduction, and flexion IMAGING • Radiographs: recommended views :AP & frog-leg lateral of both hips • Lateral radiograph is best way to identify a subtle slip • findings • Klein's line: line drawn along superior border femoral neck on AP pelvis will intersect less of the femoral head or not at all in a child with SCFE intersects lateral femoral head in a normal hip due to natural lateral overhang of the epiphysis .evaluate for asymmetry between sides • "S" sign: line drawn along inferior cortical outline of femur in frog-leg lateral view normally extends from proximal femur head/neck junction to the proximal femoral physis but in SCFE there will be a sharp turn or break in continuity of this line • epiphysiolysis (growth plate widening or lucency) • findings • Klein's line • line drawn along superior border femoral neck on AP pelvis • will intersect less of the femoral head or not at all in a child with SCFE • intersects lateral femoral head in a normal hip due to natural lateral overhang of the epiphysis • evaluate for asymmetry between sides • "S" sign • line drawn along inferior cortical outline of femur in frog-leg lateral view • normally extends from proximal femur head/neck junction to the proximal femoral physis but in SCFE there will be a sharp turn or break in continuity of this line • epiphysiolysis (growth plate widening or lucency) S.U.F.E TREATMENT
• Operative: percutaneous in situ fixation
• indications : both stable and unstable slips • Outcomes: good or excellent outcomes in >90% of cases • open epiphyseal reduction and fixation • indications (controversial): unstable and severe slips THANK YOU