Introduction Lecture for Anatomy in

Haematology Module
DR. HNIN NANDAR OO
• Sites of haemopoiesis from fetus to adult life
• Primary and secondary lymphoid organs
– Bone marrow and thymus
– Spleen, tonsil, lymph node, peyer patches and so on
THYMUS
Broad, flat, bilobed

Beneath the upper sternum

4
5
Capsule
Trabeculation

Medulla cortex

Lobules

6
Cortex

Small lymphocyte
(thymocytes)
• reticular cells
• plasma cells
• macrophage
• monocytes

7
Medulla of thymus lobule

Epithelial reticular cells Hassall's

corpuscles

Characteristic cells of medulla

Spherical
Deeply eosinophilic hyaline center
Concentrically arranged epithelioid cells

8
 Vascularization
Arterioles
Capillary

Efferent
vessels
Venules

9
Function

T cells production
Lymphocyte from bone marrow differentiate into mature T cells
Hormone Secretion
Thymulin
Thymopoietin
Thymosin
Thymic humoral factor
Hemopoiesis
During fetal life

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 SAMPLE SBA

A pathologist received tissue sample to differentiate lymphoid organs. After

tissue processing, he noticed the characteristic cell of medulla of thymus.
Which one of the folllwing cells can be found in medulla of thymus?

A. B lymphocyte
B. Hassall’s corpuscle
C. Natural killar cell
D. Plasma cell
E. Thymocyte