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Herpes Zoster
Herpes Zoster
HERPES ZOSTER
Location of
Intercostal
pathology: Facial
Lumbo-sacral
Extremities
Intercostal
Lumbar
Facial
Extremities
Etiopathogenesis
- Secondary infection or
reactivation of latent infection
- Mechanisms of reactivation are
not well understood
- T-lymphocyte depletion is
associated with reactivation
(malignancies, transplantation,
AIDS, advanced age).
- Adenitis and transient
viremia are observed at
baseline
- Acute inflammatory
response and neuronal
necrosis,
hypersensitivity and
pain.
Second phase of
replication identical
to chickenpox.
• Herpes zoster is
less contagious
Clinic
Dermatoma; it is very frequent in the branches of the
middle part of the thorax and in the upper lumbar (T3-
L2).
Start Hyperesthesia
Allodynia
Intercostal 53%.
2 to 4 days Skin lesions appear suddenly, almost never
exceeding half of the body.
12 to 24 few or abundant vesicles 2 to 3 mm in
hours diameter on an erythematous base
In racemes
3 to 4 days desiccate or turn into pustules
7 to 10 days leave ulcerations and meliceric crusts
POSTHERPETIC
NEURALGIA