ADIPOSE TISSUE

&
MYXOID TISSUE
ADIPOSE TISSUE
Connective tissue in which fat-storing cells
or adipocytes predominates is called adipose
tissue.
 Adipose
tissue

White Brown
adipose adipose
tissue tissue
Functions of adipose tissue
Energy storage
Thermal insulation
Cushioning/shock absorber
Energy homeostasis
Secretion of hormones
WHITE ADIPOCYTE
Cell Morphology:
Unilocular
 50-150micrometer,
spherical when
isolated,polyhedral /oval
insitu
Large owing to lipid
accumulation
Flattened nucleus
Thin rim of cytoplasm
H&E STAINED SECTION
Fat cells are very large
Signet ring appearence
Many with nuclei not
present
Seen empty.
In some,cytoplasm rupture
and collapse
ADIPOCYTES
AZURE STAIN
OSMIUM TETROXIDE
FROZEN SECTION - OIL RED O
BROWN ADIPOSE TISSUE
Cell Morphology :
Multilocular
Centrally placed
nucleus
Numerous
mitochondria
Brown colour
Funtion:
 Thermogenesis
BROWN ADIPOSE TISSUE-NEWBORN
MYXOID TISSUE

-Stellate cells

-Hydrated mucoid
material

-Fine meshwork of
fibres
STAINING-ALCIAN BLUE
STAINING-COLLOIDAL IRON
GROUND SUBSTANCE
Visible as blue–gray
amorphous material
(arrows)
Separating collagen bundles.
Consists of acidic
mucopolysaccharides.
Hyaluronic acid is the main
constituent of myxoid
intercellular matrix.
Small amount of sulfated
glycosaminoglycans is also
found.
 STELLATE CELLS :
• Sharing features of
smooth muscle
cells,macrophages and
dendritic cells.
• Resembles fibroblast

FIBERS :
 Resembles type 1 collagen
fibers.
Prenatally-as Whartons jelly around umbilical
cord vessels
Postnatally present in- pulp
- vitreous humor of the
eye ball
- nucleus pulposus of
intervertebral disc
DIFFERENCE
MUCOID MYXOID
Substance produced by or Similar appearing
related to epithelium substance produced by or
 specialised cells to related to connective tissue
synthesize , store,secrete cells{fibrocytes}
mucin Basophiphic granular,
Rich in stringy , and feathery
carbohydrate&small material –H/E
amount of non enzymatic Loose ct tissue – collagen
proteins. fibres , stellate cells
More in submandibular, It contains hyaluronic acid
sublingual glands’
CONCLUSION
Adipose tissue is a specialized c.t .
It comprises about 20-25% of total body weight.
Based on location divided into parital and visceral.
Based on morphology-two types white and brown
Main fuction is to store energy
It is also cosider to be an endocrine organ which
secrete several bioactive factors.(leptin,adiponectine)
Clinical relation –Obesity,Lipodystophies.
REFERENCES

Junquiera’s basic histology.

Ross histology text and atlas. 6th ed.
DiFiore’s Atlas of Histology. 11th ed.