• Distribution • Trichomonas vaginalis has a worldwide distribution. It is not especially common in tropical countries.
Dr Mamoun Magzoub PhD
• Route of transmission: • Trichomoniasis is a sexually transmitted disease. • Trichomoniasis is caused by a parasite that is passed from one person to another through sexual contact or through contact with damp objects that contain the parasite.
Dr Mamoun Magzoub PhD
• In addition, a woman can become infected if her genitals come into contact with certain objects that are infested with the parasite. These objects include: • Damp towels and wash clothes • Wet clothing, such as bathing suits Toilet seats.
Dr Mamoun Magzoub PhD
• Life Cycle: • The normal habitat of Trichomonas vaginalis are the human vagina & prostate gland. In the female host the organism typically feeds on mucosal surface of the vagina , ingesting bacteria & leukocytes & at times , being phagocytosed by macrophages. • It prefers a medium slightly alkaline or somewhat more acid than healthy vagina. • In men it may be demonstrated in the urine, urethral discharge or following massage of the prostate with emission of prostatic fluid.
Dr Mamoun Magzoub PhD
Dr Mamoun Magzoub PhD • Clinical Features & Pathology: • Inflammation, irritation and itching in the genital area (vaginitis). • There is yellow, green or gray vaginal discharge. • This is often thick and foamy, and sometimes has a strong "fish-like" odor. • Discomfort during sexual intercourse (dyspareunia) or urination (dysuria). • Soreness or itching of the labia and inner thighs. The labia may also be swollen. Lower abdominal pain (in rare cases). Dr Mamoun Magzoub PhD • The infections can present in 3 forms: • 1. Asymptomatic vaginitis. • 2. Acute or chronic volvovaginitis • 3. Urethritis. • Differential Diagnosis of acute urethritis in both women & men may be difficult. It must be distinguished from gonococcal, chlamydial , or herpetic infection.
Dr Mamoun Magzoub PhD
• Laboratory Diagnosis: • Finding Trichomonas vaginalis flagellates in unstained or stained preparations of vaginal or urethral discharges. • Motile Trichomonas vaginalis can sometimes seen in the urine of men & women. • T. vaganalis does not have a cyst form.
Dr Mamoun Magzoub PhD
Dr Mamoun Magzoub PhD Dr Mamoun Magzoub PhD Dr Mamoun Magzoub PhD Dr Mamoun Magzoub PhD • Prevention & Control: • 1.Treatment of infected partners (husband & wife). • 2.Condoms also provide a protection.
Dr Mamoun Magzoub PhD
• Treatment: • Symptomatic & asymptomatic women should be treated , & treatment is aimed at eradicating the organism. The treatment of choice for women is a single 2 g dose of metronidazole.